Rosaceiform dermatitis associated with topical tacrolimus treatment - 24/04/13
Doi : 10.1016/j.jaad.2009.01.029
Shoko Fujiwara, MD, Yukari Okubo, MD ⁎ 
, Ryokichi Irisawa, MD, Ryoji Tsuboi, MD
, Ryokichi Irisawa, MD, Ryoji Tsuboi, MD Department of Dermatology, Tokyo Medical University, Tokyo, Japan
Reprint requests: Yukari Okubo, MD, Department of Dermatology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 166-0023, Japan.Abstract |
We describe herein 3 patients who developed rosacea-like dermatitis eruptions while using 0.03% or 0.1% tacrolimus ointment for facial dermatitis. Skin biopsy specimens showed telangiectasia and noncaseating epithelioid granulomatous tissue formation in the papillary to mid dermis. Continuous topical use of immunomodulators such as tacrolimus or pimecrolimus should be regarded as a potential cause of rosaceiform dermatitis, although many cases have not been reported.
Il testo completo di questo articolo è disponibile in PDF.Key words : rosaceiform dermatitis, tacrolimus treatment
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
© 2009
American Academy of Dermatology, Inc.. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 62 - N° 6
P. 1050-1052 - giugno 2010 Ritorno al numero
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