Xanthogranulomas associated with hematologic malignancy in adulthood - 24/04/13
, Kanade Shinkai, MD, PhD, Timothy H. McCalmont, MD, Lindy P. Fox, MD
Correspondence to: Brenda A. Shoo, MD, 1701 Divisadero St, Third Floor, San Francisco, CA 94115.Abstract |
Although xanthogranulomatosis (XG), defined as multiple xanthogranulomas occurring simultaneously, was originally described in infants and children, a number of adult cases have been reported. Adult XG, which generally presents in the absence of hyperlipidemia, has many similarities to the childhood variant. Among the similarities are reports of the simultaneous development of XG and hematologic disorders. Herein we report a case of XG in a 45-year-old man with B-cell acute lymphoblastic leukemia and review the literature regarding the association of XG and hematologic disorders in adults. We propose that xanthogranulomas seen in children and adults bear many similarities, clinically and histopathologically, and share an association with hematologic malignancies.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations used : B-ALL, CML, XG
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
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| Reprints are not available from authors. |
Vol 59 - N° 3
P. 488-493 - settembre 2008 Ritorno al numero
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