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Novel EUS-guided gastrojejunostomy technique using a new double-balloon enteric tube and lumen-apposing metal stent (with videos) - 16/11/13

Doi : 10.1016/j.gie.2013.09.025 
Takao Itoi, MD, PhD, FASGE 1, , Fumihide Itokawa, MD, PhD 1, Toshio Uraoka, MD 2, Takuji Gotoda, MD, PhD, FASGE 1, Joichiro Horii, MD, PhD 2, Osamu Goto, MD, PhD 2, Fuminori Moriyasu, MD 1, Jong Ho Moon, MD, PhD 4, Yuko Kitagawa, MD, PhD 3, Naohisa Yahagi, MD, PhD 2
1 Departments of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan 
2 Division of Research and Development for Minimally Invasive Treatment, Cancer Center, School of Medicine, Keio University, Tokyo, Japan 
3 Department of Surgery, School of Medicine, Keio University, Tokyo, Japan 
4 Department of Gastroenterology, Soon Chun Hyang University School of Medicine, Seoul, Korea 

Reprint requests: Takao Itoi, MD, PhD, FASGE, Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

Abstract

Background

Surgical gastrojejunostomy is associated with relatively high morbidity and mortality rates. However, current experimental EUS-guided gastrojejunostomy information is limited.

Objective

To evaluate a novel EUS-guided gastrojejunostomy technique using a new enteric balloon and lumen-apposing metal stent.

Design

Animal experiment.

Setting

Animal laboratory at a referral center.

Subjects and Interventions

In 5 pigs, gastrojejunostomies were created under EUS guidance. Fully covered lumen-apposing stents were placed between the stomach and the jejunum.

Main Outcome Measurements

Technical success and adverse events of EUS-guided gastrojejunostomy.

Results

All stents, with 1 exception, were successfully deployed without any adverse events. The mean time to stent placement was 44.2 minutes (range 28-64 minutes). All animals showed normal eating behavior without signs of infection for 1 month after the procedure. Endoscopic imaging of the stomach site showed the stent to be patent and stable, without dislodgment, in all of the pigs. Necropsy showed complete adhesion between the stomach and the jejunum wall.

Limitations

Pilot study.

Conclusions

Creation of an EUS-guided gastrojejunostomy by using a novel enteric balloon and metal stent appears to be promising as a minimally invasive treatment.

Il testo completo di questo articolo è disponibile in PDF.

Abbreviation : SEMS


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 DISCLOSURE: The following author disclosed financial relationships relevant to this publication: Dr Itoi is a speaker for Olympus and a consultant to Xlunema. The other authors disclosed no financial relationships relevant to this publication. The novel reflected metal stents were provided free of charge by Taewoong-Medical Co Ltd (Seoul, Korea). This study was funded in part by Taewoong-Medical.
 If you would like to chat with an author of this article, you may contact Dr Itoi at itoi@tokyo-med.ac.jp.


© 2013  American Society for Gastrointestinal Endoscopy. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
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Vol 78 - N° 6

P. 934-939 - dicembre 2013 Ritorno al numero
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