Autoimmune Focal Encephalitis Shows Marked Hypermetabolism on Positron Emission Tomography - 07/03/14
Doi : 10.1016/j.jpeds.2009.07.048
Mariko Sekigawa, MD a, ⁎ 
, Akihisa Okumura, MD, PhD b, Shin-ichi Niijima, MD, PhD a, Masaharu Hayashi, MD, PhD c, Kyoko Tanaka, MD, PhD b, Toshiaki Shimizu, MD, PhD b
, Akihisa Okumura, MD, PhD b, Shin-ichi Niijima, MD, PhD a, Masaharu Hayashi, MD, PhD c, Kyoko Tanaka, MD, PhD b, Toshiaki Shimizu, MD, PhD b a Department of Pediatrics, Juntendo Nerima Hospital, Tokyo, Japan
b Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan
c Department of Clinical Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
Reprint requests: Mariko Sekigawa, MD, Department of Pediatrics, Juntendo Nerima Hospital, 3-1-10 Takanodai, Nerima-ku, Tokyo, 177-8521 Japan.Abstract |
A 22-month-old toddler presented with involuntary movements, hemiparesis, and behavioral changes. Magnetic resonance imaging showed no abnormality, but positron emission tomography (PET) showed focal hypermetabolism. By immunohistochemical technique with the patient’s sera in control brain sections, autoantibodies recognizing the same areas as found by PET scanning were identified and disappeared after intravenous immunoglobulin therapy. PET scanning may be useful in the diagnosis of autoimmune encephalitis.
Il testo completo di questo articolo è disponibile in PDF.Mots-clés : EEG, FDG-PET, IVIG, MRI
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| This work was supported by the grant from the Ministry of Education, Culture, Sports, Science and Technology (20249053). The authors declare no conflicts of interest. |
© 2010
Pubblicato da Elsevier Masson SAS.
Vol 156 - N° 1
P. 158-160 - gennaio 2010 Ritorno al numero
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