Rosacea : Part I. Introduction, categorization, histology, pathogenesis, and risk factors - 17/04/15
Abstract |
Rosacea is a chronic inflammatory skin condition that affects approximately 16 million Americans. Four distinct subtypes of rosacea have been recognized, with transient and nontransient facial flushing, telangiectasia, and inflammatory papules and pustules being among the more commonly recognized features. Although the exact pathogenesis of rosacea is unknown, dysregulation of the innate immune system, overgrowth of commensal skin organisms, and aberrant neurovascular signaling may all have a role in promoting the clinical features of rosacea.
Il testo completo di questo articolo è disponibile in PDF.Key words : cathelicidin, mast cells, matrix metalloproteinases, microbiome, rosacea, serine proteases, transient receptor potential channels, ultraviolet radiation
Abbreviations used : AMP, CagA, ETR, IL, KLK5, MMP, PAR2, PPR, ROS, TEWL, TLR2, TRPA, TRPV, UV
Mappa
| Funding sources: None. |
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| Dr Two has served as an unpaid consultant for Bayer Pharmaceuticals, Dr Gallo has served as an investigator for Bayer Pharmaceuticals and Galderma, and Dr Hata has served as an investigator for Bayer Pharmaceuticals. Dr Wu has no conflicts of interest to declare. |
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| Date of release: May 2015 |
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| Expiration date: May 2018 |
Vol 72 - N° 5
P. 749-758 - maggio 2015 Ritorno al numero
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
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