Sommario

• • ·COVID-19 vaccine equity and booster doses

    Pagina :1193

     
• • ·Beyond COVID-19—will self-sampling and testing become the norm?

    Pagina :1194-1195

    Yap Boum, Sara Eyangoh, Marie-Claire Okomo

    
• • ·Lack of detail in population-level data impedes analysis of SARS-CoV-2 variants of concern and clinical outcomes

    Pagina :1195-1197

    Sean Wei Xiang Ong, Barnaby Edward Young, David Chien Lye

    
• • ·Three are better than one—increasing HBV seroprotection by a tri-antigenic vaccine

    Pagina :1197-1198

    Florian van Bömmel, Thomas Berg

     
• • ·Zika vaccines: can we solve one problem without creating another one?

    Pagina :1198-1200

    Priscila M S Castanha, Ernesto T A Marques

     
• • ·Implementation strategies for passive respiratory syncytial virus immunisation

    Pagina :1200-1201

    Charles J Sande

     
• • ·Monoclonal antibodies as antibacterial therapies: thinking outside of the box

    Pagina :1201-1202

    Marin H Kollef, Kevin D Betthauser

     
• • ·Understanding why superspreading drives the COVID-19 pandemic but not the H1N1 pandemic

    Pagina :1203-1204

    Paul Z Chen, Marion Koopmans, David N Fisman, Frank X Gu

    
• • ·Lessons about COVID-19 vaccine hesitancy among minority ethnic people in the UK

    Pagina :1204-1206

    Seilesh Kadambari, Samantha Vanderslott

    
• • ·Is ceftriaxone similarly effective to benzylpenicillin in neurosyphilis?

    Pagina :1207

    Wujian Ke, Leiwen Fu, Bingyi Wang, Xinying Leng, Huachun Zou

    
• • ·Is ceftriaxone similarly effective to benzylpenicillin in neurosyphilis? – Authors’ reply

    Pagina :1207-1208

    Thomas Bettuzzi, Aurélie Jourdes, Guillaume Martin Blondel, Nicolas Dupin

    
• • ·Increasing clindamycin resistance in group A streptococcus

    Pagina :1208-1209

    Bryan P White, Emily A Siegrist

    
• • ·Negative antigen RDT and RT-PCR results do not rule out COVID-19 if clinical suspicion is strong

    Pagina :1209

    Fernando Kemta Lekpa, Sylvain Raoul Simeni Njonnou, Eric Balti, Henry Namme Luma, Simeon Pierre Choukem, The University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19)

     
• • ·Negative antigen RDT and RT-PCR results do not rule out COVID-19 if clinical suspicion is strong – Authors’ reply

    Pagina :1210

    Nadia Mandeng, Karl Njuwa Fai, Lisa M Bebell, Yap Boum

    
• • ·Bell’s palsy and SARS-CoV-2 vaccines—an unfolding story

    Pagina :1210-1211

    Nicola Cirillo, Richard Doan

    
• • ·Bell’s palsy and SARS-CoV-2 vaccines—an unfolding story – Authors’ reply

    Pagina :1211-1212

    Al Ozonoff, Etsuro Nanishi, Ofer Levy

    
• • ·Heterologous prime–boost vaccination with ChAdOx1 nCoV-19 and BNT162b2

    Pagina :1212-1213

    Matthias Tenbusch, Sofie Schumacher, Emanuel Vogel, Alina Priller, Jürgen Held, Philipp Steininger, Stephanie Beileke, Pascal Irrgang, Ronja Brockhoff, Jon Salmanton-García, Kathrin Tinnefeld, Hrvoje Mijocevic, Kilian Schober, Christian Bogdan, Sarah Yazici, Percy Knolle, Oliver A Cornely, Klaus Überla, Ulrike Protzer, DZIF-VACCELERATE-CoVaKo study team, Hedwig Roggendorf, Otto Zelger, Catharina Christa, Samuel Jeske, Sarah Heringer, Rayya Alsalameh, Jan Esse, Jochen Mattner, Monika Wytopil

      
• • ·The SARS-CoV-2 B.1.1.7 variant and increased clinical severity—the jury is out

    Pagina :1213-1214

    Benjamin Giles, Paul Meredith, Samuel Robson, Gary Smith, Anoop Chauhan, PACIFIC-19 and COG-UK research groups

    
• • ·Two-test or three-test strategy for routine asymptomatic testing during air travel?

    Pagina :1214-1215

    Mohammad Shahid

    
• • ·Correction to Lancet Infect Dis 2021; 21: 858–67

    Pagina :e258

    
• • ·ECCMID 2021

    Pagina :1216

    Farooq Kazi, Ammara Mushtaq

    
• • ·The long road to polio eradication

    Pagina :1217

    Vijay Shankar Balakrishnan

    
• • ·Malaria vaccine development—where are we?

    Pagina :1218

    Priya Venkatesan

    
• • ·Travel notice issued as Venezuela faces health system crisis

    Pagina :1219

    Sanjeet Bagcchi

    
• • ·Triumph in China as it is certified malaria-free by WHO

    Pagina :1220-1221

    Talha Burki

    
• • ·Infectious disease surveillance update

    Pagina :1221

    Ruth Zwizwai

    Mappa Mappa
• • ·Research in brief

    Pagina :1222

    Sharmila Devi

    Mappa Mappa
• • ·Purnell Choppin

    Pagina :1223

    Sanjeet Bagcchi

     
• • ·Marta Lado—Ebola, HIV, sexual health and more

    Pagina :1224

    Tony Kirby

     
• • ·Images of a world facing a pandemic

    Pagina :1225-1229

    Marco De Ambrogi

     
• • ·The truth inside the comedy

    Pagina :1230

    Cahal McQuillan

     
• • ·Memorialising Trump’s pandemic (non-)response

    Pagina :1231

    Vijay Shankar Balakrishnan

     
• • ·An imaginary pandemic and its consequences

    Pagina :*

    Sanjeet Bagcchi

     
• • ·Diagnostic performance of different sampling approaches for SARS-CoV-2 RT-PCR testing: a systematic review and meta-analysis

    Pagina :1233-1245

    Nicole Ngai Yung Tsang, Hau Chi So, Ka Yan Ng, Benjamin J Cowling, Gabriel M Leung, Dennis Kai Ming Ip

    Riassunto Riassunto Mappa Mappa   
• • ·Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study

    Pagina :1246-1256

    Dan Frampton, Tommy Rampling, Aidan Cross, Heather Bailey, Judith Heaney, Matthew Byott, Rebecca Scott, Rebecca Sconza, Joseph Price, Marios Margaritis, Malin Bergstrom, Moira J Spyer, Patricia B Miralhes, Paul Grant, Stuart Kirk, Chris Valerio, Zaheer Mangera, Thaventhran Prabhahar, Jeronimo Moreno-Cuesta, Nish Arulkumaran, Mervyn Singer, Gee Yen Shin, Emilie Sanchez, Stavroula M Paraskevopoulou, Deenan Pillay, Rachel A McKendry, Mariyam Mirfenderesky, Catherine F Houlihan, Eleni Nastouli

    Riassunto Riassunto Mappa Mappa   
• • ·Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2, dose-ranging study

    Pagina :1257-1270

    Paul A Goepfert, Bo Fu, Anne-Laure Chabanon, Matthew I Bonaparte, Matthew G Davis, Brandon J Essink, Ian Frank, Owen Haney, Helene Janosczyk, Michael C Keefer, Marguerite Koutsoukos, Murray A Kimmel, Roger Masotti, Stephen J Savarino, Lode Schuerman, Howard Schwartz, Lawrence D Sher, Jon Smith, Fernanda Tavares-Da-Silva, Sanjay Gurunathan, Carlos A DiazGranados, Guy de Bruyn

    Riassunto Riassunto Mappa Mappa   
• • ·Immunogenicity and safety of a tri-antigenic versus a mono-antigenic hepatitis B vaccine in adults (PROTECT): a randomised, double-blind, phase 3 trial

    Pagina :1271-1281

    Timo Vesikari, Joanne M Langley, Nathan Segall, Brian J Ward, Curtis Cooper, Guillaume Poliquin, Bruce Smith, Soren Gantt, Janet E McElhaney, Marc Dionne, Pierre van Damme, Isabel Leroux-Roels, Geert Leroux-Roels, Nathalie Machluf, Johanna N Spaans, Bebi Yassin-Rajkumar, David E Anderson, Vlad Popovic, Francisco Diaz-Mitoma, PROTECT Study Group, Timo Vesikari, Joanne M Langley, Soren Gantt, Marc Dionne, Janet McElhaney, Bruce Rankin, Carl Griffin, Mark Turner, Judith Kirstein, Barbara E Rizzardi, Hayes Williams, Anitta Ahonen, Olli Henriksson, Benita Ukkonen, Marita Paassilta, Nathan Segall, Brian J Ward, Curtis Cooper, Guillaume Poliquin, Bruce Smith, Pierre Van Damme, Isabel Leroux-Roels, Geert Leroux-Roels, Nathalie Machluf, Johanna N Spaans, Bebi Yassin-Rajkumar, David E Anderson, Vlad Popovic, Francisco Diaz-Mitoma

    Riassunto Riassunto Mappa Mappa   
• • ·Safety and immunogenicity of a purified inactivated Zika virus vaccine candidate in healthy adults: an observer-blind, randomised, phase 1 trial

    Pagina :1282-1292

    Htay-Htay Han, Clemente Diaz, Camilo J Acosta, Mengya Liu, Astrid Borkowski

    Riassunto Riassunto Mappa Mappa   
• • ·Impact of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease and pneumonia in The Gambia: 10 years of population-based surveillance

    Pagina :1293-1302

    The Gambia Pneumococcal Surveillance Group, Grant A Mackenzie, Philip C Hill, David J Jeffries, Malick Ndiaye, Shah M Sahito, Ilias Hossain, Uchendu Uchendu, David Ameh, Oyedeji Adeyemi, Jayani Pathirana, Yekini Olatunji, Baderinwa Abatan, Bilquees S Muhammad, Ebirim Ahameefula, Augustin E Fombah, Banjo Adeshola, Babila G Lobga, Debasish Saha, Roslyn Mackenzie, Aderonke Odutola, Ian D Plumb, Aliu Akano, Bernard E Ebruke, Readon C Ideh, Bankole Kuti, Peter Githua, Emmanuel Olutunde, Ogochukwu Ofordile, Edward Green, Effua Usuf, Henry Badji, Usman NA Ikumapayi, Ahmed Manjang, Rasheed Salaudeen, E David Nsekpong, Sheikh Jarju, Martin Antonio, Sana Sambou, Lamin Ceesay, Yamundow Lowe-Jallow, Sidat Fofana, Momodou Jasseh, Kim Mulholland, Maria Knoll, Orin S Levine, Stephen R Howie, Richard A Adegbola, Brian M Greenwood, Tumani Corrah

    Riassunto Riassunto Mappa Mappa   
• • ·Respiratory syncytial virus seasonality and prevention strategy planning for passive immunisation of infants in low-income and middle-income countries: a modelling study

    Pagina :1303-1312

    You Li, David Hodgson, Xin Wang, Katherine E Atkins, Daniel R Feikin, Harish Nair

    Riassunto Riassunto Mappa Mappa   
• • ·Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial

    Pagina :1313-1323

    Bruno François, Hasan S Jafri, Jean Chastre, Miguel Sánchez-García, Philippe Eggimann, Pierre-François Dequin, Vincent Huberlant, Lucia Viña Soria, Thierry Boulain, Cédric Bretonnière, Jérôme Pugin, Josep Trenado, Ana Catalina Hernandez Padilla, Omar Ali, Kathryn Shoemaker, Pin Ren, Frank E Coenjaerts, Alexey Ruzin, Olivier Barraud, Leen Timbermont, Christine Lammens, Vadryn Pierre, Yuling Wu, Julie Vignaud, Susan Colbert, Terramika Bellamy, Mark T Esser, Filip Dubovsky, Marc J Bonten, Herman Goossens, Pierre-François Laterre, COMBACTE Consortium and the SAATELLITE Study Group, Didier Chochrad, Alain Dive, Frédéric Foret, Marc Simon, Herbert Spapen, Jacques Creteur, Yves Bouckaert, Patrick Biston, Marc Bourgeois, Martin Novacek, Tomas Vymazal, Petr Svoboda, Jan Pachl, Vladimir Sramek, Michal Hanauer, Tomas Hruby, Martin Balik, Tomas Suchy, Alain Lepape, Laurent Argaud, Frédéric Dailler, Arnaud Desachy, Christophe Guitton, Alain Mercat, Ferhat Meziani, Jean-Christophe Navellou, Rene Robert, Bertrand Souweine, Jean-Marc Tadie, Adel Maamar, Djillali Annane, Fabienne Tamion, Antoine Gros, Saad Nseir, Carole Schwebel, Gilles Francony, Jean-Yves Lefrant, Francis Schneider, Matthias Gründling, Johann Motsch, Lorenz Reill, Caroline Rolfes, Tobias Welte, Oliver Cornely, Frank Bloos, Maria Deja, Katrin Schmidt, Frank Wappler, Andreas Meier-Hellmann, Apostolos Komnos, Vasileios Bekos, Vasilios Koulouras, Ioanna Soultati, Georgios Baltopoulos, Georgios Filntisis, Epaminondas Zakynthinos, Spyros Zakynthinos, Ioannis Pnevmatikos, Ildikó Krémer, Zoltán Szentkereszty, Agnes Sarkany, Zsuzsa Marjanek, Pedro Moura, Maria Consuelo Pintado Delgado, Juan Carlos Montejo González, Paula Ramirez, Antonio Torres Marti, Juan Carlos Valia, Jose Lorente, Ana Loza Vazquez, Raúl De Pablo Sanchez, Dolores Escudero, Ricard Ferrer Roca, Jean-Luc Pagani, Marco Maggiorini

    Riassunto Riassunto Mappa Mappa   
• • ·Treponema pallidum detection in lesion and non-lesion sites in men who have sex with men with early syphilis: a prospective, cross-sectional study

    Pagina :1324-1331

    Janet M Towns, David E Leslie, Ian Denham, Rebecca Wigan, Francesca Azzato, Deborah A Williamson, Darren Lee, Eric P F Chow, Christopher K Fairley, Stephen R Graves, Lei Zhang, Marcus Y Chen

    Riassunto Riassunto Mappa Mappa   
• • ·Cryptococcal meningoencephalitis: time for action

    Pagina :e259

    Katharine Elizabeth Stott, Angela Loyse, Joe N Jarvis, Melanie Alufandika, Thomas Stephen Harrison, Henry C Mwandumba, Jeremy N Day, David G Lalloo, Tihana Bicanic, John R Perfect, William Hope

    Riassunto Riassunto Mappa Mappa   
• • ·Barriers and enablers to implementing tuberculosis control strategies in EU and European Economic Area countries: a systematic review

    Pagina :e272

    Olivia Conroy, Fatima Wurie, Simon M Collin, Matt Edmunds, Gerard de Vries, Knut Lönnroth, Ibrahim Abubakar, Sarah R Anderson, Dominik Zenner

    Riassunto Riassunto Mappa Mappa   
• • ·Genomic-informed pathogen surveillance in Africa: opportunities and challenges

    Pagina :e281

    Seth C Inzaule, Sofonias K Tessema, Yenew Kebede, Ahmed E Ogwell Ouma, John N Nkengasong

    Riassunto Riassunto Mappa Mappa   
• • ·Scaling up COVID-19 rapid antigen tests: promises and challenges

    Pagina :e290

    Rosanna W Peeling, Piero L Olliaro, Debrah I Boeras, Noah Fongwen

    Riassunto Riassunto Mappa Mappa  
• • ·Importance of non-pharmaceutical interventions in lowering the viral inoculum to reduce susceptibility to infection by SARS-CoV-2 and potentially disease severity

    Pagina :e296

    Matthew A Spinelli, David V Glidden, Efstathios D Gennatas, Michel Bielecki, Chris Beyrer, George Rutherford, Henry Chambers, Eric Goosby, Monica Gandhi

    Riassunto Riassunto Mappa Mappa  
• • ·Herpetic oesophagitis in an immunocompetent infant with gastroesophageal reflux

    Pagina :1332

    Esther J E Peeters, Pauline De Bruyne, Marjolein Van Waas, Johanna C Escher, Michael Doukas, Danielle M Hendriks, Caroline E Veldhuis-Hogen Esch