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• • ·Editorial Board

    Article :112534

    

• Review Articles

  • ·Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies

    Article :112368

    Wafaa Abumustafa, Batoul Abi Zamer, Bariaa A. Khalil, Mawieh Hamad, Azzam A. Maghazachi, Jibran Sualeh Muhammad

    Résumé Résumé Plan Plan  
  • ·Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases

    Article :112179

    Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Ali Mohammad Pourbagher-Shahri, Saeed Samarghandian

    Résumé Résumé Plan Plan  
  • ·The role of aquaporin 4 (AQP4) in spinal cord injury

    Article :112384

    Qi-Lin Pan, Fei-Xiang Lin, Ning Liu, Rong-Chun Chen

    Résumé Résumé Plan Plan  
  • ·Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases

    Article :112385

    Dana Elkhalifa, Menatallah Rayan, Ahmed T. Negmeldin, Abdelbary Elhissi, Ashraf Khalil

    Résumé Résumé Plan Plan  
  • ·Composition of intestinal flora affects the risk relationship between Alzheimer's disease/Parkinson's disease and cancer

    Article :112343

    Zhongci Hang, Tong Lei, Zehua Zeng, Shanglin Cai, Wangyu Bi, Hongwu Du

    Résumé Résumé Plan Plan  
  • ·Neoechinulins: Molecular, cellular, and functional attributes as promising therapeutics against cancer and other human diseases

    Article :112378

    Sicon Mitra, Uttpal Anand, Rupa Sanyal, Niraj Kumar Jha, Tapan Behl, Avinash Mundhra, Arabinda Ghosh, Manoj Kumar, Jarosław Proćków, Abhijit Dey

    Résumé Résumé Plan Plan  
  • ·Gene regulation by antisense transcription: A focus on neurological and cancer diseases

    Article :112265

    Sajad Najafi, Shing Cheng Tan, Pourya Raee, Yazdan Rahmati, Yahya Asemani, E.Hui Clarissa Lee, Kiavash Hushmandi, Ali Zarrabi, Amir Reza Aref, Milad Ashrafizadeh, Alan Prem Kumar, Yavuz Nuri Ertas, Sepideh Ghani, Shahin Aghamiri

    Résumé Résumé Plan Plan  
  • ·Advances of microneedles in hormone delivery

    Article :112393

    Thuy Trang Nguyen, Thi Thuy Dung Nguyen, Nguyen-Minh-An Tran, Giau Van Vo

    Résumé Résumé Plan Plan  
  • ·Transitioning pre-clinical glioblastoma models to clinical settings with biomarkers identified in 3D cell-based models: A systematic scoping review

    Article :112396

    Brandon Wee Siang Phon, Muhamad N.A. Kamarudin, Saatheeyavaane Bhuvanendran, Ammu K. Radhakrishnan

    Résumé Résumé Plan Plan   
  • ·Natural and chemical compounds as protective agents against cardiac lipotoxicity

    Article :112413

    Fatemeh Yarmohammadi, A. Wallace Hayes, Gholamreza Karimi

    Résumé Résumé Plan Plan  
  • ·Toward the next-generation phyto-nanomedicines: cell-derived nanovesicles (CDNs) for natural product delivery

    Article :112416

    Chaoxiang Chen, Jialin Wang, Mengdi Sun, Jian Li, Hui-Min David Wang

    Résumé Résumé Plan Plan  
  • ·The dual role of microRNA-9 in gastrointestinal cancers: oncomiR or tumor suppressor?

    Article :112394

    Afsane Bahrami, Amirsajad Jafari, Gordon A. Ferns

    Résumé Résumé Plan Plan  
  • ·Lessons from Epstein-Barr virus DNA detection in cerebrospinal fluid as a diagnostic tool for EBV-induced central nervous system dysfunction among HIV-positive patients

    Article :112392

    Yanli Wang, Jun Yang, Ying Wen

    Résumé Résumé Plan Plan  
  • ·Neutrophil accumulation within tissues: A damage x healing dichotomy

    Article :112422

    Karen Marques Oliveira-Costa, Gustavo B. Menezes, Heitor A. Paula Neto

    Résumé Résumé Plan Plan  
  • ·Review of anticancer potentials and structure-activity relationships (SAR) of rhodanine derivatives

    Article :112406

    Lim Ju Yin, Ahmad Khairul Daniel bin Ahmad Kamar, Gan Tjin Fung, Chin Tze Liang, Vasudeva Rao Avupati

    Résumé Résumé Plan Plan  
  • ·Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications

    Article :112419

    Jamal Majidpoor, Keywan Mortezaee

    Résumé Résumé Plan Plan  
  • ·Emerging role of long non-coding RNAs in endothelial dysfunction and their molecular mechanisms

    Article :112421

    Ravichandran Jayasuriya, Kumar Ganesan, Baojun Xu, Kunka Mohanram Ramkumar

    Résumé Résumé Plan Plan  
  • ·Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action

    Article :112397

    Zhong-Yuan Tang, Yang Li, Yu-Ting Tang, Xiao-Dong Ma, Ze-Yao Tang

    Résumé Résumé Plan Plan  
  • ·The molecular mechanisms of ferroptosis and its role in cardiovascular disease

    Article :112423

    Yang Zhang, Laiyun Xin, Mi Xiang, Chang Shang, Yuling Wang, Yan Wang, Xiangning Cui, Yingdong Lu

    Résumé Résumé Plan Plan  
  • ·Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

    Article :112420

    Masoumeh Farahani, Zahra Niknam, Leila Mohammadi Amirabad, Nasrin Amiri-Dashatan, Mehdi Koushki, Mohadeseh Nemati, Fahima Danesh Pouya, Mostafa Rezaei-Tavirani, Yousef Rasmi, Lobat Tayebi

    Résumé Résumé Plan Plan  
  • ·mTOR pathway: A potential therapeutic target for spinal cord injury

    Article :112430

    Yi Ding, Qin Chen

    Résumé Résumé Plan Plan  
  • ·The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer

    Article :112429

    Sonja Oehmcke-Hecht, Peggy Berlin, Brigitte Müller-Hilke, Bernd Kreikemeyer, Praveen Vasudevan, Larissa Henze, Valeria Khaimov, Brigitte Vollmar, Robert David, Claudia Maletzki

    Résumé Résumé Plan Plan  
  • ·Clinical and immunological aspects of microRNAs in neonatal sepsis

    Article :112444

    Ahlam Fatmi, Nafissa Chabni, María Cernada, Máximo Vento, María González-López, Mourad Aribi, Federico V. Pallardó, José Luis García-Giménez

    Résumé Résumé Plan Plan  
  • ·Current status of intratumour microbiome in cancer and engineered exogenous microbiota as a promising therapeutic strategy

    Article :112443

    Jiawen Chen, Ting Li, Jianhao Liang, Qiqi Huang, Jian-Dong Huang, Yiquan Ke, Haitao Sun

    Résumé Résumé Plan Plan  
  • ·Non-pharmacologic strategies for the management of intestinal inflammation

    Article :112414

    Tatiani Uceli Maioli, Luísa Martins Trindade, Aline Souza, Lícia Torres, Maria Emília Rabelo Andrade, Valbert Nascimento Cardoso, Simone Vasconcelos Generoso

    Résumé Résumé Plan Plan  
  • ·Current status on the therapeutic strategies for heart failure and diabetic cardiomyopathy

    Article :112463

    Amy Hyein Kim, Jung Eun Jang, Jin Han

    Résumé Résumé Plan Plan  
  • ·Dopamine, a co-regulatory component, bridges the central nervous system and the immune system

    Article :112458

    Mingan Li, Lin Zhou, Xiaohui Sun, Yunqi Yang, Ce Zhang, Tian Wang, Fenghua Fu

    Résumé Résumé Plan Plan  
  • ·Therapeutic potential of targeting cathepsin S in pulmonary fibrosis

    Article :112245

    YoungJo Yoo, Eun Choi, Yejin Kim, Yunyoung Cha, Eunhye Um, Younghwa Kim, Yunji Kim, Yun-Sil Lee

    Résumé Résumé Plan Plan  
  • ·Advances in biomedical study of the myopia-related signaling pathways and mechanisms

    Article :112472

    Jing Yang, Xinli Ouyang, Hong Fu, Xinyu Hou, Yan Liu, Yongfang Xie, Haiqun Yu, Guohui Wang

    Résumé Résumé Plan Plan  
  • ·Animal models of diabetic microvascular complications: Relevance to clinical features

    Article :112305

    Randhir Singh, Shah Asma Farooq, Ashi Mannan, Thakur Gurjeet Singh, Agnieszka Najda, Zawiślak Grażyna, Ghadeer M. Albadrani, Amany A. Sayed, Mohamed M. Abdel-Daim

    Résumé Résumé Plan Plan  
  • ·Dual role of microbiota-derived short-chain fatty acids on host and pathogen

    Article :112352

    Rasoul Mirzaei, Elahe Dehkhodaie, Behnaz Bouzari, Mandana Rahimi, Abolfazl Gholestani, Seyed Reza Hosseini-Fard, Hossein Keyvani, Ali Teimoori, Sajad Karampoor

    Résumé Résumé Plan Plan  
  • ·Drugs repurposed: An advanced step towards the treatment of breast cancer and associated challenges

    Article :112375

    Jonaid Ahmad Malik, Sakeel Ahmed, Bisma Jan, Onur Bender, Turki Al Hagbani, Aali Alqarni, Sirajudheen Anwar

    Résumé Résumé Plan Plan  

• Original Articles

  • ·Iron chelation therapy with deferiprone improves oxidative status and red blood cell quality and reduces redox-active iron in β-thalassemia/hemoglobin E patients

    Article :112381

    Noppawan Phumala Morales, Supot Rodrat, Pannaree Piromkraipak, Paveena Yamanont, Kittiphong Paiboonsukwong, Suthat Fucharoen

    Résumé Résumé Plan Plan  
  • ·Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction

    Article :112367

    Yafen Wang, Xiangnan Kuang, Yujie Yin, Ningxin Han, Liping Chang, Hongtao Wang, Yunlong Hou, Huixin Li, Zhen Li, Yi Liu, Yuanjie Hao, Yaru Wei, Xiaoqi Wang, Zhenhua Jia

    Résumé Résumé Plan Plan   
  • ·Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect

    Article :112383

    Linhua Deng, Wei Liu, Qiang Xu, Rui Guo, Dapeng Zhang, Jingyu Ni, Lan Li, Xiaoyue Cai, Guanwei Fan, Yingqiang Zhao

    Résumé Résumé Plan Plan   
  • ·Translation inhibition and suppression of stress granules formation by cisplatin

    Article :112382

    Paulina Pietras, Anaïs Aulas, Marta M. Fay, Marta Leśniczak-Staszak, Mateusz Sowiński, Shawn M. Lyons, Witold Szaflarski, Pavel Ivanov

    Résumé Résumé Plan Plan   
  • ·Structural mechanism underlying the differential effects of ivermectin and moxidectin on the C. elegans glutamate-gated chloride channel GLC-2

    Article :112380

    Mark D. Kaji, Jennifer D. Noonan, Timothy G. Geary, Robin N. Beech

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  • ·Protective mechanisms of telmisartan against hepatic ischemia/reperfusion injury in rats may involve PPARγ-induced TLR4/NF-κB suppression

    Article :112374

    Mohamed A. Morsy, Seham A. Abdel-Gaber, Rehab A. Rifaai, Mostafa M. Mohammed, Anroop B. Nair, Walaa Yehia Abdelzaher

    Résumé Résumé Plan Plan  
  • ·Novel doxorubicin / folate-targeted trans-ferulic acid-loaded PLGA nanoparticles combination: In-vivo superiority over standard chemotherapeutic regimen for breast cancer treatment

    Article :112376

    Sahar A. Helmy, Saif El-Mofty, Amal M. El Gayar, Ibrahim M. El-Sherbiny, Yousra M. El-Far

    Résumé Résumé Plan Plan   
  • ·Anti-fibrotic effect of 6-bromo-indirubin-3′-oxime (6-BIO) via regulation of activator protein-1 (AP-1) and specificity protein-1 (SP-1) transcription factors in kidney cells

    Article :112402

    Jung Sun Park, In Ae Jung, Hong Sang Choi, Dong-Hyun Kim, Hoon In Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim

    Résumé Résumé Plan Plan   
  • ·Sinapic acid ameliorates cardiac dysfunction and cardiomyopathy by modulating NF-κB and Nrf2/HO-1 signaling pathways in streptozocin induced diabetic rats

    Article :112412

    Mohammad Raish, Ajaz Ahmad, Yousef A. Bin Jardan, Mudassar Shahid, Khalid M. Alkharfy, Abdul Ahad, Mushtaq Ahmad Ansari, Ibrahim Abdelsalam Abdelrahman, Fahad I. Al-Jenoobi

    Résumé Résumé Plan Plan  
  • ·Anti-asthmatic effects of Phlomis umbrosa Turczaninow using ovalbumin induced asthma murine model and network pharmacology analysis

    Article :112410

    So-Won Pak, A Yeong Lee, Yun-Soo Seo, Se-Jin Lee, Woong-Il Kim, Dong-Ho Shin, Jong-Choon Kim, Joong-Sun Kim, Je-Oh Lim, In-Sik Shin

    Résumé Résumé Plan Plan   
  • ·Inosine mitigated diabetic peripheral neuropathy via modulating GLO1/AGEs/RAGE/NF-κB/Nrf2 and TGF-β/PKC/TRPV1 signaling pathways

    Article :112395

    Noha F. Abdelkader, Sherehan M. Ibrahim, Passant E. Moustafa, Marawan A. Elbaset

    Résumé Résumé Plan Plan   
  • ·Butylated hydroxyl-toluene, 2,4-Di-tert-butylphenol, and phytol of Chlorella sp. protect the PC12 cell line against H₂O₂-induced neurotoxicity

    Article :112415

    Saeed Niazi Vahdati, Ali Lashkari, Sepideh Aliniaye Navasatli, Susan Kabudanian Ardestani, Maliheh Safavi

    Résumé Résumé Plan Plan  
  • ·Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met, Wnt/β-catenin, and PI3K/Akt/mTOR signaling pathways

    Article :112409

    Nour Y.S. Yassin, Sameh F. AbouZid, Asmaa M. El-Kalaawy, Tarek M. Ali, Mazen M. Almehmadi, Osama M. Ahmed

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  • ·DA-9805 protects dopaminergic neurons from endoplasmic reticulum stress and inflammation

    Article :112389

    Sora Kang, Ying Piao, Young Cheol Kang, Suyeol Lim, Youngmi Kim Pak

    Résumé Résumé Plan Plan   
  • ·Pentoxifylline, a nonselective phosphodiesterase inhibitor, in adjunctive therapy in patients with irritable bowel syndrome treated with mebeverine

    Article :112399

    Sahar M. El‑Haggar, Sahar K. Hegazy, Sherief M. Abd-Elsalam, Mostafa M. Bahaa

    Résumé Résumé Plan Plan  
  • ·Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients

    Article :112407

    Huijie Lu, Haixia Jiang, Siyao Yang, Chengcheng Li, Chuanjiang Li, Ruifan Shao, Pai Zhang, Daoyi Wang, Zhiwei Liu, Huana Qi, Yinuan Cai, Wenbin Xu, Xiaojie Bao, Hailan Wang, Liang Li

    Résumé Résumé Plan Plan   
  • ·Paroxetine mitigates cardiac remodelling by doxorubicin and increases survival

    Article :112411

    Marija Kosić, Zorica Nešić, Sofija Glumac, Marko Vasić, Vladislav Pajović, Bojana Savić, Nina Japundžić-Žigon

    Résumé Résumé Plan Plan  
  • ·HCV eradication with DAAs differently affects HIV males and females: A whole miRNA sequencing characterization

    Article :112405

    Daniel Valle-Millares, Óscar Brochado-Kith, Alicia Gómez-Sanz, Luz Martín-Carbonero, Pablo Ryan, Ignacio De los Santos, Juan M. Castro, Jesús Troya, Mario Mayoral-Muñoz, Guillermo Cuevas, Paula Martínez-Román, Jesús Sanz-Sanz, María Muñoz-Muñoz, María Á Jiménez-Sousa, Salvador Resino, Verónica Briz, Amanda Fernández-Rodríguez, On behalf of multidisciplinary Group of viral coinfection HIV/Hepatitis (COVIHEP)

    Résumé Résumé Plan Plan   
  • ·Establishment of a rotavirus-infected zebrafish model and its application in drug screening

    Article :112398

    Lijun Song, Xuemei Zhu, Yujing Zhou, Yuxuan Feng, Guiqin Dai, Jiabo Chen, Yang Chen, Feng Li, Wenchang Zhao

    Résumé Résumé Plan Plan  
  • ·Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction

    Article :112404

    Ling Li, Bo Fang, Yinglei Zhang, Liuqing Yan, Yuxin He, Linfeng Hu, Qifei Xu, Qiang Li, Xianling Dai, Qin Kuang, Minxuan Xu, Jun Tan, Chenxu Ge

    Résumé Résumé Plan Plan   
  • ·Synergistic antidiabetic activity of Taraxacum officinale (L.) Weber ex F.H.Wigg and Momordica charantia L. polyherbal combination

    Article :112401

    Nithiyaa Perumal, Meenakshii Nallappan, Shamarina Shohaimi, Nur Kartinee Kassim, Thiam Tsui Tee, Yew Hoong Cheah

    Résumé Résumé Plan Plan  
  • ·Exploring the antiplatelet activity of serotonin 5-HT_2A receptor antagonists bearing 6-fluorobenzo[d]isoxazol-3-yl)propyl) motif– as potential therapeutic agents in the prevention of cardiovascular diseases

    Article :112424

    Monika Marcinkowska, Monika Kubacka, Agnieszka Zagorska, Anna Jaromin, Nikola Fajkis-Zajaczkowska, Marcin Kolaczkowski

    Résumé Résumé Plan Plan  
  • ·Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) is overexpressed in cholangiocarcinoma and its expression correlates with S100 calcium-binding protein A4 (S100A4)

    Article :112403

    Michele A. Rodrigues, Dawidson A. Gomes, Ana Luiza Cosme, Marcelo Dias Sanches, Vivian Resende, Geovanni D. Cassali

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  • ·Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A

    Article :112431

    Hung-Yu Lin, Hsing-Ju Wu, Si-Yun Chen, Ming-Feng Hou, Chang-Shen Lin, Pei-Yi Chu

    Résumé Résumé Plan Plan  
  • ·Calenduloside E protects against myocardial ischemia-reperfusion injury induced calcium overload by enhancing autophagy and inhibiting L-type Ca²⁺ channels through BAG3

    Article :112432

    Ruiying Wang, Min Wang, Bo Liu, Huibo Xu, Jingxue Ye, Xiaobo Sun, Guibo Sun

    Résumé Résumé Plan Plan   
  • ·The modulating effect of methoxy-derivatives of 2’-hydroxychalcones on the release of IL-8, MIF, VCAM-1 and ICAM-1 by colon cancer cells

    Article :112428

    Joanna Bronikowska, Małgorzata Kłósek, Tomasz Janeczko, Edyta Kostrzewa-Susłow, Zenon P. Czuba

    Résumé Résumé Plan Plan  
  • ·Plasma profiling reveals a blood-based metabolic fingerprint of obstructive sleep apnea

    Article :112425

    Lucía Pinilla, Iván D. Benítez, Fernando Santamaria-Martos, Adriano Targa, Anna Moncusí-Moix, Mireia Dalmases, Olga Mínguez, Maria Aguilà, Mariona Jové, Joaquim Sol, Reinald Pamplona, Ferran Barbé, Manuel Sánchez-de-la-Torre

    Résumé Résumé Plan Plan   
  • ·Sodium thiosulfate-supplemented UW solution protects renal grafts against prolonged cold ischemia-reperfusion injury in a murine model of syngeneic kidney transplantation

    Article :112435

    Max Y. Zhang, George J. Dugbartey, Smriti Juriasingani, Masoud Akbari, Winnie Liu, Aaron Haig, Patrick McLeod, Jacqueline Arp, Alp Sener

    Résumé Résumé Plan Plan   
  • ·DEHP mediates drug resistance by directly targeting AhR in human breast cancer

    Article :112400

    Tsung-Hua Hsieh, Chia-Yi Hsu, Pei-Jing Yang, Chien-Chih Chiu, Shih-Shin Liang, Fu Ou-Yang, Jung-Yu Kan, Ming-Feng Hou, Tsu-Nai Wang, Eing-Mei Tsai

    Résumé Résumé Plan Plan   
  • ·Baicalein suppresses lipopolysaccharide-induced acute lung injury by regulating Drp1-dependent mitochondrial fission of macrophages

    Article :112408

    Cheng Jiang, Jiechun Zhang, Huiwen Xie, Huiting Guan, Rui Li, Caixia Chen, Hongzhen Dong, You Zhou, Wei Zhang

    Résumé Résumé Plan Plan   
  • ·Paralog- and ortholog-specificity of inhibitors of human and mouse lipoxygenase-isoforms

    Article :112434

    Kumar Reddy Kakularam, Felix Karst, Aparoy Polamarasetty, Igor Ivanov, Dagmar Heydeck, Hartmut Kuhn

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  • ·SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice

    Article :112441

    Kisoo Pahk, Sang Gil Lee, Chanmin Joung, Eun-Ok Kim, Hyun Woo Kwon, Dong Hwi Kim, Jong-Ik Hwang, Sungeun Kim, Won-Ki Kim

    Résumé Résumé Plan Plan   
  • ·Eugenosedin-A improves obesity-related hyperglycemia by regulating ATP-sensitive K⁺ channels and insulin secretion in pancreatic β cells

    Article :112447

    Rong-Jyh Lin, Yu-Kwan Yen, Chien-Hsing Lee, Su-Ling Hsieh, Yu-Chin Chang, Yung-Shun Juan, Cheng-Yu Long, Kuo-Ping Shen, Bin-Nan Wu

    Résumé Résumé Plan Plan  
  • ·Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination

    Article :112436

    A.D. Rivera, F. Pieropan, G. Williams, F. Calzolari, A.M. Butt, K. Azim

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  • ·Mucin secretory action of capsaicin prevents high fat diet-induced gut barrier dysfunction in C57BL/6 mice colon

    Article :112452

    Vijay Kumar, Vibhu Kumar, Neha Mahajan, Jasleen Kaur, Kirti Devi, Ravinder Naik Dharavath, Ravindra Pal Singh, Kanthi Kiran Kondepudi, Mahendra Bishnoi

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  • ·Cordycepin suppresses glutamatergic and GABAergic synaptic transmission through activation of A₁ adenosine receptor in rat hippocampal CA1 pyramidal neurons

    Article :112446

    Jinxiu Wang, Yanchun Gong, Haoyuan Tan, Wenxi Li, Baiyi Yan, Chunfang Cheng, Juan Wan, Wei Sun, Chunhua Yuan, Li-Hua Yao

    Résumé Résumé Plan Plan  
  • ·A canthin-6-one derivative induces cell death by apoptosis/necroptosis-like with DNA damage in acute myeloid cells

    Article :112439

    Heron F.V. Torquato, Manoel Trindade Rodrigues Junior, Cauê Santos Lima, Roberto Theodoro de Araujo Júnior, Fernanda Talhati, Dhebora Albuquerque Dias, Giselle Zenker Justo, Alice Teixeira Ferreira, Ronaldo Aloise Pilli, Edgar J. Paredes-Gamero

    Résumé Résumé Plan Plan   
  • ·Xi-Xian-Tong-Shuan capsule alleviates vascular cognitive impairment in chronic cerebral hypoperfusion rats by promoting white matter repair, reducing neuronal loss, and inhibiting the expression of pro-inflammatory factors

    Article :112453

    Feng Yan, Yue Tian, Yuyou Huang, Qi Wang, Ping Liu, Ningqun Wang, Fangfang Zhao, Liyuan Zhong, Wuhan Hui, Yumin Luo

    Résumé Résumé Plan Plan  
  • ·Single-cell transcriptome analysis of Bisphenol A exposure reveals the key roles of the testicular microenvironment in male reproduction

    Article :112449

    Ning Zhang, Yinuo Wang, Ziyu Chen, Jianhong Ren, Abdur Rehman, Dawood Warraich Ahmad, Deyu Long, Junyao Hou, Yaqi Zhou, Luyu Yang, Yu Ni, Yayu Li, Changjian Du, Yingcui Yu, Mingzhi Liao

    Résumé Résumé Plan Plan   
  • ·Discontinuation of PTH therapy amplifies bone loss by increasing oxidative stress: An event ameliorated by sequential IL-17 neutralizing antibody therapy

    Article :112390

    Krishna Bhan Singh, Reena Rai, Sonu Khanka, Divya Singh

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  • ·Metformin action over gut microbiota is related to weight and glycemic control in gestational diabetes mellitus: A randomized trial

    Article :112465

    María Molina-Vega, María J. Picón-César, Carolina Gutiérrez-Repiso, Andrea Fernández-Valero, Fuensanta Lima-Rubio, Stella González-Romero, Isabel Moreno-Indias, Francisco J. Tinahones

    Résumé Résumé Plan Plan   
  • ·Methyl ferulic acid ameliorates alcohol-induced hepatic insulin resistance via miR-378b-mediated activation of PI3K-AKT pathway

    Article :112462

    Yan Zhang, Jun Lu, Yu-juan Zhong, Cheng-fang Yang, Li Chen, Dan Wu, Meng-wei Song, Lin Shi, Zu-heng Ma, Li Li, Yong-wen Li

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  • ·Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin

    Article :112461

    Wannita Klinngam, Phetploy Rungkamoltip, Saowarose Thongin, Jaruwan Joothamongkhon, Phattharachanok Khumkhrong, Mattaka Khongkow, Katawut Namdee, Surapun Tepaamorndech, Puxvadee Chaikul, Mayuree Kanlayavattanakul, Nattaya Lourith, Kitiya Piboonprai, Uracha Ruktanonchai, Udom Asawapirom, Tawin Iempridee

    Résumé Résumé Plan Plan   
  • ·The ATF3 inducer protects against diet-induced obesity via suppressing adipocyte adipogenesis and promoting lipolysis and browning

    Article :112440

    Hui-Chen Ku, Tsai-Yun Chan, Jia-Fang Chung, Yung-Hsi Kao, Ching-Feng Cheng

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  • ·Anti-arthritic activity of the flavonoids fraction of ivy leaves (Hedera helix L.) standardized extract in adjuvant induced arthritis model in rats in relation to its metabolite profile using LC/MS

    Article :112456

    Aya A. Shokry, Riham A. El-Shiekh, Gehan Kamel, Alaa F. Bakr, Dina Sabry, Amer Ramadan

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  • ·Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

    Article :112455

    Amir Mohamed Abdelhamid, Sameh Saber, Mahmoud E. Youssef, Ahmed Gaafar Ahmed Gaafar, Hanan Eissa, Marwa A. Abd-Eldayem, Mohammed Alqarni, Gaber El-Saber Batiha, Ahmad J. Obaidullah, Mohamed Awad Shahien, Eman El-Ahwany, Noha A. Amin, Mohamed Ali Etman, Mohamed M.Y. Kaddah, Eslam E. Abd El-Fattah

    Résumé Résumé Plan Plan  
  • ·Effect of kaempferol on hedgehog signaling pathway in rats with ‐‐chronic atrophic gastritis – Based on network pharmacological screening and experimental verification

    Article :112451

    Wenling Tu, Yinjie Hong, Miaoan Huang, Meimei Chen, Huijuan Gan

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  • ·Effect and mechanism of “Danggui–kushen” herb pair on ischemic heart disease

    Article :112450

    Pei liang Dong, Hui Li, Xiao jin Yu, Qing na Li, Jia qi Liu, Cai yan Liu, Hua Han

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  • ·Gut microbiota of patients with type 2 diabetes and gastrointestinal intolerance to metformin differs in composition and functionality from tolerant patients

    Article :112448

    Cristina Ma Díaz-Perdigones, Araceli Muñoz-Garach, María Dolores Álvarez-Bermúdez, Isabel Moreno-Indias, Francisco J. Tinahones

    Résumé Résumé Plan Plan  
  • ·Construction of a circRNA-miRNA-mRNA network revealed the potential mechanism of Buyang Huanwu Decoction in the treatment of cerebral ischemia

    Article :112445

    Bowei Chen, Jian Yi, Yaqian Xu, Piao Zheng, Rongmei Tang, Baiyan Liu

    Résumé Résumé Plan Plan   
  • ·Revealing the suppressive role of protein kinase C delta and p38 mitogen-activated protein kinase (MAPK)/NF-κB axis associates with lenvatinib-inhibited progression in hepatocellular carcinoma in vitro and in vivo

    Article :112437

    Ching-Hsuan Wu, Fei-Ting Hsu, Tsu-Lan Chao, Yuan-Hao Lee, Yu-Cheng Kuo

    Résumé Résumé Plan Plan   
  • ·The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib

    Article :112391

    Katarína Vavrová, Radek Indra, Petr Pompach, Zbyněk Heger, Petr Hodek

    Résumé Résumé Plan Plan  
  • ·Synthesis compound XCR-7a ameliorates LPS-induced inflammatory response by inhibiting the phosphorylation of c-Fos

    Article :112468

    Haimei Tang, Prasanta Roy, Qianqian Di, Xingyu Ma, Yue Xiao, Zherui Wu, Jiazheng Quan, Jiajing Zhao, Weilie Xiao, Weilin Chen

    Résumé Résumé Plan Plan   
  • ·Gardenia jasminoides extract ameliorates DfE-induced atopic dermatitis in mice through restoration of barrier function and T-helper 2-mediated immune response

    Article :112344

    Sun Haeng Park, Seol Jang, Ho Kyoung Kim

    Résumé Résumé Plan Plan  
  • ·Nanostructured systems increase the in vitro cytotoxic effect of bullfrog oil in human melanoma cells (A2058)

    Article :112438

    W.N. Oliveira, E.N. Alencar, H.A.O. Rocha, L. Amaral-Machado, E.S.T. Egito

    Résumé Résumé Plan Plan  
  • ·Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players

    Article :112460

    Patrice Marques, Elena Domingo, Arantxa Rubio, Sergio Martinez-Hervás, Juan F. Ascaso, Laura Piqueras, José T. Real, Maria-Jesus Sanz

    Résumé Résumé Plan Plan   
  • ·Melatonin pre-treated bone marrow derived-mesenchymal stem cells prompt wound healing in rat models

    Article :112473

    Aljohara M. Al-Otaibi, Asma S. Al-Gebaly, Rafa Almeer, Gadah Albasher, Wedad S. Al-Qahtani, Ahmed E. Abdel Moneim

    Résumé Résumé Plan Plan  
  • ·Structural modulation of gut microbiota during alleviation of experimental passive Heymann nephritis in rats by a traditional Chinese herbal formula

    Article :112475

    Xin-Hui Wang, Ya-Nan Yang, Ying Liang, Rui Lang, Qin Zeng, Lei Yan, Ren-Huan Yu, Chong-Ming Wu

    Résumé Résumé Plan Plan   
  • ·Membrane model as key tool in the study of glutathione-s-transferase mediated anticancer drug resistance

    Article :112426

    Elsa M. Materón, Flavio M. Shimizu, Kevin Figueiredo dos Santos, Gustavo F. Nascimento, Vananélia P.N. Geraldo, Osvaldo N. Oliveira Jr, Ronaldo C. Faria

    Résumé Résumé Plan Plan   
  • ·Photodynamic therapy with the dual-mode association of IR780 to PEG-PLA nanocapsules and the effects on human breast cancer cells

    Article :112464

    Marina Guimarães Carvalho Machado, Maria Alice de Oliveira, Elisa Gomes Lanna, Raoni Pais Siqueira, Gwenaelle Pound-Lana, Renata Tupinambá Branquinho, Vanessa Carla Furtado Mosqueira

    Résumé Résumé Plan Plan  
  • ·Repurposing an atherosclerosis targeting peptide for tumor imaging

    Article :112469

    Luciana Kovacs, Ryan A. Davis, Tanushree Ganguly, Roger Chammas, Julie L. Sutcliffe

    Résumé Résumé Plan Plan   
  • ·Aspirin and Sulindac act via different mechanisms to inhibit store-operated calcium channel: Implications for colorectal cancer metastasis

    Article :112476

    Yu-Shiuan Wang, Nai-Kuei Huang, Yu-Chiao Lin, Wei-Chiao Chang, Wan-Chen Huang

    Résumé Résumé Plan Plan   
  • ·Preventive effects of cristacarpin on experimentally induced uveitis by targeting NF-κB

    Article :112474

    Su Jung Hwang, Won Keun Oh, Ho-Young Lee, Hyo-Jong Lee

    Résumé Résumé Plan Plan  
  • ·Identification of early diagnostic biomarkers via WGCNA in gastric cancer

    Article :112477

    Zohreh Rezaei, Javad Ranjbaran, Hossein Safarpour, Samira Nomiri, Fatemeh Salmani, Elham Chamani, Pegah Larki, Oronzo Brunetti, Nicola Silvestris, Tahmine Tavakoli

    Résumé Résumé Plan Plan   
  • ·Immunostimulatory properties of heat-resistant RNA in a decoction of Glycyrrhizae Radix

    Article :112457

    Akiko Inujima, Keiichi Koizumi, Naotoshi Shibahara

    Résumé Résumé Plan Plan   
  • ·Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson’s disease

    Article :112479

    Fumiaki Sato, Yoki Nakamura, Simeng Ma, Takahiro Kochi, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Norimitsu Morioka

    Résumé Résumé Plan Plan  
  • ·Trans-placental transfer of nicotine: Modulation by organic cation transporters

    Article :112489

    I-Hsin Lin, Ling Yang, Jeffrey W. Dalley, Tung-Hu Tsai

    Résumé Résumé Plan Plan   
  • ·Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro

    Article :112480

    Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky

    Résumé Résumé Plan Plan   
  • ·A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency

    Article :112482

    Chwan-Fwu Lin, Shih-Yi Chuang, Tse-Hung Huang, Thi My Huyen Nguyen, Pei-Wen Wang, Ahmed Alalaiwe, Jia-You Fang

    Résumé Résumé Plan Plan   
  • ·Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy

    Article :112122

    Abdallah M. Gendy, Mohamed R. Elnagar, Mona M. Allam, Mohamed R. Mousa, Ahmed E. Khodir, Alaadin E. El-Haddad, Osama S. Elnahas, Sahar M. Fayez, Shereen S. El-Mancy

    Résumé Résumé Plan Plan   
  • ·Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study

    Article :112243

    Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Vaddi Suryaprakash, Kosagi-Sharaf Rao, Nobunao Ikewaki, Tohru Sonoda, Gary A. Levy, Masaru Iwasaki, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel JK Abraham

    Résumé Résumé Plan Plan  
  • ·Glyphaeaside C- enriched extract of Glyphaea brevis restored the antioxidant and reproductive integrity of 1,4-Dinitrobenzene-intoxicated rats

    Article :112359

    Janet Olayemi Olugbodi, Mary Tolulope Olaleye, Gomaa Mostafa-Hedeab, Mohammed Alqarni, Omotayo Babatunde Ilesanmi, Gaber El-Saber Batiha, Afolabi Clement Akinmoladun

    Résumé Résumé Plan Plan  
  • ·Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage

    Article :112361

    Isabel González-Mariscal, Macarena Pozo-Morales, Silvana Y. Romero-Zerbo, Vanesa Espinosa-Jimenez, Alejandro Escamilla-Sánchez, Lourdes Sánchez-Salido, Nadia Cobo-Vuilleumier, Benoit R. Gauthier, Francisco J. Bermúdez-Silva

    Résumé Résumé Plan Plan   
  • ·Mechanism of Infantile Feire Kechuan Oral Solution against Mycoplasma pneumoniae infection of A549 cells

    Article :112366

    Ruijie Wan, Minyi Jia, Haiwei Dou, Peng Tu, Dawei Shi, Qing Yuan, Deli Xin

    Résumé Résumé Plan Plan  
  • ·Silencing tumor-intrinsic CD73 enhances the chemosensitivity of NSCLC and potentiates the anti-tumoral effects of cisplatin: An in vitro study

    Article :112370

    Elham Baghbani, Saeed Noorolyai, Shima Rahmani, Dariush Shanehbandi, Mahdi Abdoli Shadbad, Leili Aghebati-Maleki, Ahad Mokhtarzadeh, Oronzo Brunetti, Rossella Fasano, Nicola Silvestris, Behzad Baradaran

    Résumé Résumé Plan Plan  
  • ·Toxicological and pharmacological effects of pentacyclic triterpenes rich fraction obtained from the leaves of Mansoa hirsuta

    Article :112478

    Joquebede Rodrigues Pereira, Aldilane Gonçalves da Fonseca, Luzia Leiros de Sena Fernandes, Allanny Alves Furtado, Valéria Costa da Silva, Valdir Florêncio da Veiga Júnior, Antônio Euzébio Goulart Sant’Ana, Cláudia Nunes Oliveira, Gerlane Coelho Bernardo Guerra, Matheus de Freitas Fernandes-Pedrosa, Elaine Cristina Gavioli, José Fernando Oliveira-Costa, Milena Botelho Pereira Soares, Ádley Antonini Neves de Lima, Daniel de Melo Silva, Telma Maria Araújo Moura Lemos

    Résumé Résumé Plan Plan  
  • ·The inhibitory role of benzo-dioxole-piperamide on the phosphorylation process as an NF-Kappa B silencer

    Article :112471

    Sajad Shahbazi, Tara Zakerali

    Résumé Résumé Plan Plan   
  • ·Dose-dependent effects of Hedyotis diffusa extract on the pharmacokinetics of tamoxifen, 4-hydroxytamoxifen, and N-desmethyltamoxifen

    Article :112466

    Yung-Yi Cheng, Elise T. Tuzo, Jeffrey W. Dalley, Tung-Hu Tsai

    Résumé Résumé Plan Plan  

• Short Communication

  • ·Ursolic acid does not change the cytokine levels following resistance training in healthy men: A pilot balanced, double-blind and placebo-controlled clinical trial

    Article :112289

    Patrícia Cristina Barreto Lobo, Gustavo Duarte Pimentel

    Résumé Résumé Plan Plan  

• Letters to the Editor

  • ·Ginsenoside Rg3 inhibits angiogenesis in gastric precancerous lesions through downregulation of Glut1 and Glut4

    Article :112086

    Zhongzhen Zeng, Qing Nian, Nianzhi Chen, Maoyuan Zhao, Qiao Zheng, Gang Zhang, Ziyi Zhao, Yu Chen, Jundong Wang, Jinhao Zeng, Daoyin Gong, Jianyuan Tang

    Résumé Résumé Plan Plan  

• Retractions

  • ·Retraction notice to: "Arbutin attenuates hydrogen peroxide-induced oxidative injury through regulation of microRNA-29a in retinal ganglion cells" [Biomed. Pharmacother. 112 (2019) 108729]

    Article :112508

    Wenbo Zhao, Shuai Wang, Tingyu Qin, Wenzhan Wang

    
  • ·Retraction notice to: "Long noncoding RNA RMRP upregulation aggravates myocardial ischemia-reperfusion injury by sponging miR-206 to target ATG3 expression" [Biomed. Pharmacother. 109 (2018) 716–725]

    Article :112510

    Fei Kong, Juan Jin, Xiaolin Lv, Yubo Han, Xue Liang, Yanyu Gao, Xinglin Duan

    
  • ·Retraction notice to "lncRNA PEG10 promotes cell survival, invasion and migration by sponging miR-134 in human bladder cancer" [Biomed. Pharmacother. 114 (2019) 108814]

    Article :112511

    Fuquan Jiang, Wenqian Qi, Yao Wang, Weihua Wang, Li Fan