Idiopathic Inflammatory Myopathies - 17/07/14
, Richard J. Barohn, MD b, Anthony A. Amato, MD cRésumé |
The idiopathic inflammatory myopathies (IIM) consist of rare heterogeneous autoimmune disorders that present with marked proximal and symmetric muscle weakness, except for distal and asymmetric weakness in inclusion body myositis. Despite many similarities, the IIM are fairly heterogeneous from the histopathologic and pathogenetic standpoints, and also show some clinical and treatment-response differences. The field has witnessed significant advances in our understanding of the pathophysiology and treatment of these rare disorders. This review focuses on dermatomyositis, polymyositis, and necrotizing myopathy, and examines current and promising therapies.
Le texte complet de cet article est disponible en PDF.Keywords : Polymyositis, Dermatomyositis, Necrotizing myopathy, Inclusion body myositis, Clinical presentation, Diagnosis, Pathology, Treatment
Plan
| This publication was supported by an Institutional Clinical and Translational Science Award, National Institutes of Health/National Center for Advancing Translational Sciences Grant Number UL1TR000001. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. |
Vol 32 - N° 3
P. 595-628 - août 2014 Retour au numéro
Article précédent
- A Pattern Recognition Approach to Patients with a Suspected Myopathy
- Richard J. Barohn, Mazen M. Dimachkie, Carlayne E. Jackson
- Inclusion Body Myositis
- Mazen M. Dimachkie, Richard J. Barohn
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