Adherence to topical therapy increases around the time of office visits - 19/08/11
, Fabian T. Camacho, MS b, Jennifer Krejci-Manwaring, MD a, Christie L. Carroll, MD a, Rajesh Balkrishnan, PhD c
Correspondence to: Steven R. Feldman, MD, PhD, Department of Dermatology, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27104.Winston-Salem, North Carolina, and Columbus, Ohio
Abstract |
Background |
The efficacy of topical medications is limited by non-adherence. Interventions to improve adherence to topical treatments are not well characterized.
Objective |
To assess the impact of office visits on patients’ adherence to topical treatment.
Methods |
Twenty-nine subjects enrolled in a clinical trial for psoriasis and were followed for up to 8 weeks. Subjects were told to apply 6% salicylic acid gel twice daily. Electronic monitors were used to assess adherence. Results were compared to adherence in clinical trials of hand dermatitis and atopic dermatitis.
Results |
Adherence rates were significantly higher around the time of office visits (P < .05).
Limitations |
This is a small study in a limited patient population. The study was observational and not a randomized trial of the effect of increased office visits.
Conclusion |
Frequent follow-up visits in clinical trials increase patients’ adherence to medications. The use of a follow-up visit shortly after initiating treatment may be an effective way to boost patients’ use of their medication and achieve better treatment outcomes.
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| Supported in part by Astellas Pharma US, Inc. The Center for Dermatology Research is funded by a grant from Galderma Laboratories, LP. Disclosure: Dr Feldman has had research and speaking support from Astellas Pharma and Galderma Laboratories. Dr Krejci-Manwaring has received consulting support from Connetics and Bioform Medical. Drs Camacho, Carroll, and Balkrishnan have no conflicts of interest to declare. Reprints not available from the authors. |
Vol 57 - N° 1
P. 81-83 - luglio 2007 Ritorno al numero
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