Sommario

• • ·Editorial Board

    Articolo :111434

    

• Review Articles

  • ·4-Aminoquinoline compounds from the Spanish flu to COVID-19

    Articolo :111138

    Roberto Barbosa Bazotte, Sandro Massao Hirabara, Tamires Afonso Duarte Serdan, Raquel Bragante Gritte, Talita Souza-Siqueira, Renata Gorjao, Laureane Nunes Masi, Marina Masetto Antunes, Vinicius Cruzat, Tania Cristina Pithon-Curi, Rui Curi

    Riassunto Riassunto Mappa Mappa  
  • ·Imaging genomics for accurate diagnosis and treatment of tumors: A cutting edge overview

    Articolo :111173

    Zhen Liu, Kefeng Wu, Binhua Wu, Xiaoning Tang, Huiqing Yuan, Hao Pang, Yongmei Huang, Xiao Zhu, Hui Luo, Yi Qi

    Riassunto Riassunto Mappa Mappa  
  • ·The role of heat shock proteins in the regulation of fibrotic diseases

    Articolo :111067

    Xiaoling Zhang, Xiaoyan Zhang, Wenmin Huang, Xiaoqun Ge

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  • ·Alpiniae oxyphyllae Fructus and Alzheimer’s disease: An update and current perspective on this traditional Chinese medicine

    Articolo :111167

    Jia Li, Qiuzheng Du, Na Li, Shuzhang Du, Zhi Sun

    Riassunto Riassunto Mappa Mappa  
  • ·Circulating exosomes in cardiovascular disease: Novel carriers of biological information

    Articolo :111148

    Qing Liu, Hulin Piao, Yong Wang, Dongdong Zheng, Weitie Wang

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  • ·A multi-omics view of the complex mechanism of vascular calcification

    Articolo :111192

    Yongjiang Qian, Lihua Li, Zhen Sun, Jia Liu, Wei Yuan, Zhongqun Wang

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  • ·An update on the role of miR-124 in the pathogenesis of human disorders

    Articolo :111198

    Soudeh Ghafouri-Fard, Hamed Shoorei, Zahra Bahroudi, Atefe Abak, Jamal Majidpoor, Mohammad Taheri

    Riassunto Riassunto Mappa Mappa  
  • ·Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies

    Articolo :111191

    Yao Wang, Ying Wang, Ming Yang, Xingjie Ma

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  • ·The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacological treatment

    Articolo :111200

    Esmé Jansen van Vuren, Stephan F. Steyn, Christiaan B. Brink, Marisa Möller, Francois P. Viljoen, Brian H. Harvey

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  • ·The interplay between non-coding RNAs and Twist1 signaling contribute to human disorders

    Articolo :111220

    Soudeh Ghafouri-Fard, Atefe Abak, Zahra Bahroudi, Hamed Shoorei, Sayed Haidar Abbas Raza, Mohammad Taheri

    Riassunto Riassunto Mappa Mappa  
  • ·TTN-AS1 as a potential diagnostic and prognostic biomarker for multiple cancers

    Articolo :111169

    Qiu-Xian Zheng, Jing Wang, Xin-yu Gu, Chun-Hong Huang, Chao Chen, Meng Hong, Zhi Chen

    Riassunto Riassunto Mappa Mappa  
  • ·The dual functions of the long noncoding RNA CASC15 in malignancy

    Articolo :111212

    Xinyu Gu, Qingfei Chu, Qiuxian Zheng, Jing Wang, Haihong Zhu

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  • ·The critical roles of lncRNAs in the development of osteosarcoma

    Articolo :111217

    Soudeh Ghafouri-Fard, Zeinab Shirvani-Farsani, Bashdar Mahmud Hussen, Mohammad Taheri

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  • ·Molecular targets for the management of cancer using Curcuma longa Linn. phytoconstituents: A Review

    Articolo :111078

    Sabira Sultana, Naveed Munir, Zahed Mahmood, Muhammad Riaz, Muhammad Akram, Maksim Rebezov, Nazira Kuderinova, Zhanar Moldabayeva, Mohammad Ali Shariati, Abdur Rauf, Kannan R.R. Rengasamy

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  • ·The interplay between IQGAP1 and small GTPases in cancer metastasis

    Articolo :111243

    Xiafeng Peng, Tiejun Wang, Han Gao, Xin Yue, Weiqi Bian, Jie Mei, Yan Zhang

    Riassunto Riassunto Mappa Mappa  
  • ·microRNA-140: A miRNA with diverse roles in human diseases

    Articolo :111256

    Soudeh Ghafouri-Fard, Zahra Bahroudi, Hamed Shoorei, Atefe Abak, Maliheh Ahin, Mohammad Taheri

    Riassunto Riassunto Mappa Mappa  
  • ·COVID-19 and inflammatory bowel disease: A pathophysiological assessment

    Articolo :111233

    Chunxiu Yang, Shu-Yuan Xiao

    Riassunto Riassunto Mappa Mappa  
  • ·The intestinal microbiota as a therapeutic target in the treatment of NAFLD and ALD

    Articolo :111235

    Weifang Huang, Desong Kong

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• Original Articles

  • ·Processed meat products with added plant antioxidants affect the microbiota and immune response in C57BL/6JRj mice with cyclically induced chronic inflammation

    Articolo :111133

    Stina Burri, Kajsa Granheimer, Marine Rémy, Vandana Tannira, Yunjeong So, Kimmo Rumpunen, Eva Tornberg, Pamela Canaviri Paz, Elisabeth Uhlig, Elin Oscarsson, Anne-Marie Rohrstock, Milladur Rahman, Åsa Håkansson

    Riassunto Riassunto Mappa Mappa  
  • ·Babao Dan improves neurocognitive function by inhibiting inflammation in clinical minimal hepatic encephalopathy

    Articolo :111084

    Bingjie Lu, Chao Wu, Nisma Lena Bahaji Azami, Dong Xie, Changqing Zhao, Wan Xu, Dengcheng Hui, Xi Chen, Runfei Sun, Jingru Song, Yongtong An, Kun Li, Huijun Wang, Guan Ye, Mingyu Sun

    Riassunto Riassunto Mappa Mappa   
  • ·Improvements in estrogen deficiency-induced hypercholesterolemia by Hypericum perforatum L. extract are associated with gut microbiota and related metabolites in ovariectomized (OVX) rats

    Articolo :111131

    Lin Chen, Yanru Liu, Zhishu Tang, Xinbo Shi, Zhongxing Song, Fan Cao, Peifeng Wei, Min Li, Xiaohong Li, Dahai Jiang, Yafeng Yan, Ningjuan Yang

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  • ·Outer membrane protein a in Acinetobacter baumannii induces autophagy through mTOR signalling pathways in the lung of SD rats

    Articolo :111034

    Dan Zhao, Yumei Li, Chunhong Peng, Jieru Lin, Fuxun Yu, Yichen Zhao, Xiangyan Zhang, Degang Zhao

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  • ·Novel bioactive properties of low-polarity fractions from sea-buckthorn extracts (Elaeagnus rhamnoides (L.) A. Nelson) – (in vitro)

    Articolo :111141

    B. Marciniak, R. Kontek, J. ?uchowski, A. Stochmal

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  • ·PSB 603 – a known selective adenosine A2B receptor antagonist – has anti-inflammatory activity in mice

    Articolo :111164

    Magdalena Kota?ska, Ma?gorzata Szafarz, Kamil Mika, Anna Dziubina, Marek Bednarski, Christa E. Müller, Jacek Sapa, Katarzyna Kie?-Kononowicz

    Riassunto Riassunto Mappa Mappa  
  • ·Protective effect of a mixture of marigold and rosemary extracts on UV-induced photoaging in mice

    Articolo :111178

    Joong-Hyuck Auh, Jayashree Madhavan

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  • ·Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver

    Articolo :111181

    Yasuyuki Tamai, Zhen Chen, Yue Wu, Jun Okabe, Yoshinao Kobayashi, Hitoshi Chiba, Shu-Ping Hui, Akiko Eguchi, Motoh Iwasa, Masaaki Ito, Yoshiyuki Takei

    Riassunto Riassunto Mappa Mappa   
  • ·Pure total flavonoids from citrus attenuate non-alcoholic steatohepatitis via regulating the gut microbiota and bile acid metabolism in mice

    Articolo :111183

    Beihui He, Jianping Jiang, Zheng Shi, Liyan Wu, Junbin Yan, Zheng Chen, Minmin Luo, Dawei Cui, Sumei Xu, Maoxiang Yan, Shuo Zhang, Zhiyun Chen

    Riassunto Riassunto Mappa Mappa  
  • ·Mycophenolate mediated remodeling of gut microbiota and improvement of gut-brain axis in spontaneously hypertensive rats

    Articolo :111189

    Iñaki Robles-Vera, Néstor de la Visitación, Marta Toral, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Miguel Romero, Juan Duarte

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  • ·Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway

    Articolo :111184

    Xin Xu, Xiaofang Xie, Huiqiong Zhang, Pei Wang, Gangmin Li, Junren Chen, Guanru Chen, Xiaoyu Cao, Liang Xiong, Fu Peng, Cheng Peng

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  • ·Novel N,N-di-alkylnaphthoimidazolium derivative of ?-lapachone impaired Trypanosoma cruzi mitochondrial electron transport system

    Articolo :111186

    Ana Cristina S. Bombaça, Leonardo A. Silva, Otávio Augusto Chaves, Lorrainy S. da Silva, Juliana M.C. Barbosa, Ari M. da Silva, Aurélio B.B. Ferreira, Rubem F.S. Menna-Barreto

    Riassunto Riassunto Mappa Mappa   
  • ·New insight into the role of isorhamnetin as a regulator of insulin signaling pathway in type 2 diabetes mellitus rat model: Molecular and computational approach

    Articolo :111176

    Marwa Matboli, Maha Saad, Amany Helmy Hasanin, Lobna A. Saleh, Walaa Baher, Miram M. Bekhet, Sanaa Eissa

    Riassunto Riassunto Mappa Mappa   
  • ·Role of the global gut microbial community in the development of colitis-associated cancer in a murine model

    Articolo :111206

    Jae Gon Lee, Yu-ra Lee, A-reum Lee, Chan Hyuk Park, Dong Soo Han, Chang Soo Eun

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  • ·Optimization of culture medium for Sanghuangporus vaninii and a study on its therapeutic effects on gout

    Articolo :111194

    Qiong Guo, Liying Zhao, Yuhua Zhu, Jiang Wu, Cuiting Hao, Shuang Song, Wei Shi

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  • ·Nuanxin capsule enhances cardiac function by inhibiting oxidative stress-induced mitochondrial dependent apoptosis through AMPK/JNK signaling pathway

    Articolo :111188

    Tiantian Lou, Jin Ma, Yanzheng Xie, Gengzhen Yao, Ye Fan, Shiyu Ma, Xu Zou

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  • ·Sinomenine protects bone from destruction to ameliorate arthritis via activating p62^{Thr269/Ser272}-Keap1-Nrf2 feedback loop

    Articolo :111195

    Kangsheng Liao, Xiaohui Su, Kawai Lei, Zhongqiu Liu, Linlin Lu, Qibiao Wu, Hudan Pan, Qingchun Huang, Yue Zhao, Mingming Wang, Jiye Cai, Liang Liu, Ting Li

    Riassunto Riassunto Mappa Mappa   
  • ·Hongjingtian injection protects against myocardial ischemia reperfusion-induced apoptosis by blocking ROS induced autophagic- flux

    Articolo :111205

    Jing Zhao, Jiwei Zhang, Qian Liu, Yingchao Wang, Yecheng Jin, Yingxin Yang, Cheng Ni, Ling Zhang

    Riassunto Riassunto Mappa Mappa  
  • ·Foeniculum vulgare seed extract induces apoptosis in lung cancer cells partly through the down-regulation of Bcl-2

    Articolo :111213

    Weiwei Ke, Xiangxuan Zhao, Zaiming Lu

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  • ·Effect of atorvastatin versus rosuvastatin on inflammatory biomarkers and LV function in type 2 diabetic patients with dyslipidemia

    Articolo :111179

    Rehab Werida, Ibtsam Khairat, Naglaa F. Khedr

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  • ·d-Mannose suppresses osteoarthritis development in vivo and delays IL-1?-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway

    Articolo :111199

    Zhiming Lin, Jianing Miao, Tao Zhang, Ming He, Xiaonan Zhou, He Zhang, Yue Gao, Lunhao Bai

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  • ·Drug-drug interactions between salvianolate injection and aspirin based on their metabolic enzymes

    Articolo :111203

    Weiyi Cao, Qiaoning Yang, Wantong Zhang, Yonggang Xu, Shuge Wang, Yi Wu, Yang Zhao, Zhongning Guo, Rui Li, Rui Gao

    Riassunto Riassunto Mappa Mappa   
  • ·Anti-nociceptive effects of Sedum Lineare Thunb. on spared nerve injury-induced neuropathic pain by inhibiting TLR4/NF-?B signaling in the spinal cord in rats

    Articolo :111215

    Xin-ying Wang, Hai-juan Ma, Meng Xue, Ya-lan Sun, An Ren, Meng-qi Li, Zhi-hua Huang, Cheng Huang

    Riassunto Riassunto Mappa Mappa  
  • ·Pretreatment of Blumea lacera leaves ameliorate acute ulcer and oxidative stress in ethanol-induced Long-Evan rat: A combined experimental and chemico-biological interaction

    Articolo :111211

    Md. Amjad Hossen, A.S.M. Ali Reza, A.M. Abu Ahmed, Md. Kamrul Islam, Israt Jahan, Rahni Hossain, Mohammad Forhad Khan, Mohammad Rifat Alam Maruf, Md. Areeful Haque, Md. Atiar Rahman

    Riassunto Riassunto Mappa Mappa  
  • ·Development of a zebrafish screening model for diabetic retinopathy induced by hyperglycemia: Reproducibility verification in animal model

    Articolo :111201

    Yujin Lee, Jaewook Yang

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  • ·Suppression of delayed rectifier K⁺ channels by gentamicin induces membrane hyperexcitability through JNK and PKA signaling pathways in vestibular ganglion neurons

    Articolo :111185

    Yunmei Zhang, Yuan Zhang, Zizhang Wang, Yufang Sun, Xinghong Jiang, Man Xue, Yafeng Yu, Jin Tao

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  • ·Therapeutic effects of blocking ?-catenin against hepatocellular carcinoma-induced activation of inflammation, fibrosis and tumor invasion

    Articolo :111216

    Hanan M. Hassan, Sherif M H El-Kannishy, Abdullah Alattar, Reem Alshaman, Ahmed M Hamdan, Mohammed M H Al-Gayyar

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  • ·Halofuginone regulates keloid fibroblast fibrotic response to TGF-? induction

    Articolo :111182

    Pierre Marty, Brice Chatelain, Thomas Lihoreau, Marion Tissot, Zélie Dirand, Philippe Humbert, Clémence Senez, Eleonora Secomandi, Ciro Isidoro, Gwenaël Rolin

    Riassunto Riassunto Mappa Mappa  
  • ·The protective effect of 1-methyltryptophan isomers in renal ischemia-reperfusion injury is not exclusively dependent on indolamine 2,3-dioxygenase inhibition

    Articolo :111180

    Diana ?epcová, Ido P. Kema, Maria Sandovici, Leo E. Deelman, Katarína Šišková, Ján Klimas, Peter Vavrinec, Diana Vavrincová-Yaghi

    Riassunto Riassunto Mappa Mappa   
  • ·Renoprotective effects of enzyme-hydrolyzed polysaccharides from Auricularia polytricha on adenine-induced chronic kidney diseases in mice

    Articolo :111004

    Xinling Song, Hui Pang, Weijun Cui, Jianjun Zhang, Jian Li, Le Jia

    Riassunto Riassunto Mappa Mappa  
  • ·Bioequivalence study of two perindopril tert-butylamine tablet formulations in healthy Chinese subjects under fasting and fed conditions: A randomized, open-label, single-dose, crossover trial

    Articolo :111221

    Qiuying Li, Zhen Hao, Yan Yu, Yunbiao Tang

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  • ·Revealing hypoglycemic and hypolipidemic mechanism of Xiaokeyinshui extract combination on streptozotocin-induced diabetic mice in high sucrose/high fat diet by metabolomics and lipidomics

    Articolo :111219

    Zhinan Xiang, Haifei Xie, Qilin Tong, Jun Pan, Luosheng Wan, Jinbo Fang, Jiachun Chen

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  • ·The effect of nutmeg essential oil constituents on Novikoff hepatoma cell viability and communication through Cx43 gap junctions

    Articolo :111229

    Rokas Mickus, Gintar? Jan?iuk?, Vytautas Raškevi?ius, Valeryia Mikalayeva, Inga Matulyt?, Mindaugas Marksa, K?stutis Maci?nas, Jurga Bernatonien?, Vytenis Arvydas Skeberdis

    Riassunto Riassunto Mappa Mappa   
  • ·Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia via the TRAF6/TAK1/MEK/NF-?B pathway

    Articolo :111197

    Bo-Ram Jin, Jae-Yun Ju, Agung Nugroho, Minho Lee, Hyo-Jin An

    Riassunto Riassunto Mappa Mappa  
  • ·Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway

    Articolo :111187

    Liucen Wu, Qian Yan, Fenglian Chen, Cheng Cao, Shuling Wang

    Riassunto Riassunto Mappa Mappa   
  • ·In-vivo wound healing activity of a novel composite sponge loaded with mucilage and lipoidal matter of Hibiscus species

    Articolo :111225

    Riham O. Bakr, Reham I. Amer, Dalia Attia, Mai M. Abdelhafez, Asmaa K. Al-Mokaddem, Abd El-Nasser G. El-Gendy, Ahlam M. El-Fishawy, Marwa A.A. Fayed, Sameh S. Gad

    Riassunto Riassunto Mappa Mappa  
  • ·H₂S prevents peripheral immune cell invasion, increasing [Ca²⁺]i and excessive phagocytosis following hypoxia-ischemia injury in neonatal mice

    Articolo :111207

    Tingting Li, Xili Chu, Danqing Xin, Hongfei Ke, Shuhan Wang, Dexiang Liu, Wenqiang Chen, Zhen Wang

    Riassunto Riassunto Mappa Mappa   
  • ·Ameliorative effects of endurance training and Matricaria chamomilla flowers hydroethanolic extract on cognitive deficit in type 2 diabetes rats

    Articolo :111230

    Ali Heidarianpour, Fereshteh Mohammadi, Maryam Keshvari, Naser Mirazi

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  • ·Role of peripheral 5-HT_1D, 5-HT₃ and 5-HT₇ receptors in the mechanical allodynia induced by serotonin in mice

    Articolo :111210

    Elias B. Nascimento, Thiago R.L. Romero, Marcela M.G.B. Dutra, Bernd L. Fiebich, Igor D.G. Duarte, Márcio M. Coelho

    Riassunto Riassunto Mappa Mappa  
  • ·A strategy for component-based Chinese medicines design approach of Polygonum orientale L. against hypoxia/reoxygenation based on uniform design-stepwise regression-simulated annealing

    Articolo :111177

    Siqi Wan, Jinfang Zhang, Rong Hou, Minsi Zheng, Liya Liu, Mingshuo Zhang, Zhiyong Li, Xiulan Huang

    Riassunto Riassunto Mappa Mappa  
  • ·Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats

    Articolo :111246

    Redouane Rebai, Luc Jasmin, Abdennacer Boudah

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  • ·Investigation of the molecular mechanism underlying the inhibitory activities of ethanol extract of Bombyx mori pupa-incubated Cordyceps militaris fruiting bodies toward allergic rhinitis

    Articolo :111248

    Ting-Feng Wu, Wan-Yin Shi, Yi-Chen Chiu, Yu-Yi Chan

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  • ·Influence of progestational stress on BDNF and NMDARs in the hippocampus of male offspring and amelioration by Chaihu Shugan San

    Articolo :111204

    Ya-hui Xu, Xin-xing Wang, Ming-jing Wang, Yue-yun Liu, Zhe Xue, Jia-xu Chen

    Riassunto Riassunto Mappa Mappa