Sommaire

Numéro précédent | Numéro suivant

• • ·Editorial Board

    Article :117662

    

• Review Articles

  • ·The therapeutic potential of andrographolide in cancer treatment

    Article :117438

    Jiaxuan Hu, Yi Li, Xin Xie, Yunlei Song, Wenjing Yan, Yan Luo, Yumao Jiang

    Résumé Résumé Plan Plan  
  • ·A comprehensive review of Co₃O nanostructures in cancer: Synthesis, characterization, reactive oxygen species mechanisms, and therapeutic applications

    Article :117457

    Negar Bayati-Komitaki, Safaa H. Ganduh, Asaad H. Alzaidy, Masoud Salavati-Niasari

    Résumé Résumé Plan Plan  
  • ·Matricellular proteins: From cardiac homeostasis to immune regulation

    Article :117463

    Li Meng, Hui-min Chen, Jia-sheng Zhang, Yi-rong Wu, Yi-zhou Xu

    Résumé Résumé Plan Plan  
  • ·The role of liquid-liquid phase separation in the disease pathogenesis and drug development

    Article :117448

    Yingjie Zhang, Chengkang Jin, Xiaoling Xu, Junping Guo, Lijun Wang

    Résumé Résumé Plan Plan  
  • ·Curcumin and nanodelivery systems: New directions for targeted therapy and diagnosis of breast cancer

    Article :117404

    Yao Zhou, Jie Gong, Xianguang Deng, Lele Shen, Shiting Wu, Hongqiao Fan, Lifang Liu

    Résumé Résumé Plan Plan  
  • ·Evaluating the safety and efficiency of nanomaterials: A focus on mitochondrial health

    Article :117484

    Liu Siquan, Cheng Weilin, Chen Xiuwen, Zou Meiyan, Guo Weihong, Feng Xiaoli

    Résumé Résumé Plan Plan  
  • ·Beyond conventional treatment: ASGR1 Leading the new era of hypercholesterolemia management

    Article :117488

    Jiali Song, Yang Fang, Xiuqin Rao, Luojia Wu, Chenxi Zhang, Jun Ying, Fuzhou Hua, Yue Lin, Gen Wei

    Résumé Résumé Plan Plan  
  • ·CTC-neutrophil interaction: A key driver and therapeutic target of cancer metastasis

    Article :117474

    Chengyi Hu, Ling Long, Jie Lou, Mingjing Leng, Qingqing Yang, Xiang Xu, Xing Zhou

    Résumé Résumé Plan Plan  
  • ·Application of hydrogels for targeting cancer stem cells in cancer treatment

    Article :117486

    Fashun Li, Zhipeng Li, Chen Wei, Long Xu, Yan Liang, Jianqin Yan, Yifei Li, Bin He, Chong Sun

    Résumé Résumé Plan Plan  
  • ·Mitochondrial metabolism regulated macrophage phenotype in myocardial infarction

    Article :117494

    Youli Kong, Qing Zhang, Shiqi Wang, Ran Li, Chenying Fu, Quan Wei

    Résumé Résumé Plan Plan  
  • ·Innovative lipid nanoparticles: A cutting-edge approach for potential renal cell carcinoma therapeutics

    Article :117465

    Asif Shahzad, Zhuoran Teng, Muhammad Yameen, Wenjing Liu, Kun Cui, Xiangjie Liu, Yijian Sun, Qiuxin Duan, JiaoJiao Xia, Yurong Dong, Ziyuan Bai, Dongmei Peng, Jinshan Zhang, Zhe Xu, Jiang Pi, Zhe Yang, Qiao Zhang

    Résumé Résumé Plan Plan  
  • ·Involvement of SIRT1-mediated cellular immune response in cancer

    Article :117482

    Nan Liu, Jiafang Li, Hui Dai, Xinyue Liang, Hongqiong Fan

    Résumé Résumé Plan Plan  
  • ·Potential mechanisms of Treponema pallidum breaching the blood-brain barrier

    Article :117478

    Yiming Zhou, Yafeng Xie, Man Xu

    Résumé Résumé Plan Plan  
  • ·Molecular biological mechanisms of radiotherapy-induced skin injury occurrence and treatment

    Article :117470

    Jie Cui, Tie-Jun Wang, Yu-Xuan Zhang, Li-Zhen She, Yue-Chen Zhao

    Résumé Résumé Plan Plan  
  • ·Anethole in cancer therapy: Mechanisms, synergistic potential, and clinical challenges

    Article :117449

    António Raposo, Dele Raheem, Renata Puppin Zandonadi, Narinder Suri, Adeola Olukosi, Bernardo Romão de Lima, Conrado Carrascosa, Javad Sharifi-Rad, Hyungseo Bobby Ryu, Heesup Han, Daniela Calina

    Résumé Résumé Plan Plan  
  • ·Therapeutic prospects of sex hormone receptor signaling in hormone-responsive cancers

    Article :117473

    Alex Boye, Silas Acheampong Osei, Augustine Suurinobah Brah

    Résumé Résumé Plan Plan  
  • ·DPP-IV as a potential candidate in anti-obesity and obesity-related diseases treatment

    Article :117464

    Xin Guo, Huolun Feng, Liyang Cai, Jiabin Zheng, Yong Li

    Résumé Résumé Plan Plan  
  • ·Investigation of the molecular mechanisms underlying the anti-inflammatory and antitumour effects of isorhapontigenin: Insights from in vitro and in vivo studies

    Article :117479

    Tomasz Kowalczyk, Janusz Piekarski, Anna Merecz-Sadowska, Martyna Muskała, Przemysław Sitarek

    Résumé Résumé Plan Plan  
  • ·PSF-lncRNA interaction as a target for novel targeted anticancer therapies

    Article :117491

    Ren Liu, Xiaojing Wang, Min Zhou, Jingfang Zhai, Jie Sun

    Résumé Résumé Plan Plan  
  • ·Natural Compounds for Bone Remodeling: Targeting osteoblasts and relevant signaling pathways

    Article :117490

    Zechao Qu, Songchuan Zhao, Yong Zhang, Xiaohao Wang, Liang Yan

    Résumé Résumé Plan Plan  
  • ·Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment

    Article :117516

    J.P. Jose Merlin, Heidi Abrahamse

    Résumé Résumé Plan Plan  
  • ·Nuclear factor erythroid 2-related factor-mediated signaling alleviates ferroptosis during cerebral ischemia-reperfusion injury

    Article :117513

    Zheng Li, Jihong Xing

    Résumé Résumé Plan Plan  
  • ·Potential therapeutic application and mechanism of gut microbiota-derived extracellular vesicles in polycystic ovary syndrome

    Article :117504

    Liangliang Yang, Tingxiu Liu, Yan Liao, Yuehan Ren, Zheng Zheng, Mingyue Zhang, Yue Yu, Chang Liu, Chaoying Wang, Tong Chen, Lili Zhang, Dongxue Zheng, Haidan Zhao, Zhexin Ni, Xinmin Liu

    Résumé Résumé Plan Plan  
  • ·Research advances in signaling pathways related to the malignant progression of HSIL to invasive cervical cancer: A review

    Article :117483

    Huifang Wang, Chang Liu, Keer Jin, Xiang Li, Jiaxin Zheng, Danbo Wang

    Résumé Résumé Plan Plan  
  • ·Advances in stimuli-responsive gold nanorods for drug-delivery and targeted therapy systems

    Article :117493

    Sakineh Hajebi, Mohsen Chamanara, Shadi Sadat Nasiri, Mahsa Ghasri, Alireza Mouraki, Reza Heidari, Abbas Nourmohammadi

    Résumé Résumé Plan Plan  
  • ·Dysbiosis and diabetic foot ulcers: A metabolic perspective of Staphylococcus aureus infection

    Article :117498

    Ruisi Liu, Jiawei Feng, Yiming Ni, Kaixin Chen, Yuqing Wang, Ting Zhang, Mingmei Zhou, Cheng Zhao

    Résumé Résumé Plan Plan  
  • ·Neutrophil extracellular traps and cardiovascular disease: Associations and potential therapeutic approaches

    Article :117476

    Yiyue Tang, Yang Jiao, Xiaohua An, Qingxian Tu, Qianfeng Jiang

    Résumé Résumé Plan Plan  
  • ·The role of hepatocyte-derived extracellular vesicles in liver and extrahepatic diseases

    Article :117502

    Shihui Li, Fang Cheng, Zhuan Zhang, Ruizi Xu, Honglei Shi, Yongmin Yan

    Résumé Résumé Plan Plan  
  • ·Unlocking the potential of extracellular vesicle circRNAs in breast cancer: From molecular mechanisms to therapeutic horizons

    Article :117480

    Lijuan Fang, Zehua Zhu, Mingyue Han, Shaojie Li, Xiangyi Kong, Lusen Yang

    Résumé Résumé Plan Plan  
  • ·Stapled peptides as potential therapeutics for diabetes and other metabolic diseases

    Article :117496

    Dominika Nielipińska, Dominika Rubiak, Agnieszka J. Pietrzyk-Brzezińska, Joanna Małolepsza, Katarzyna M. Błażewska, Edyta Gendaszewska-Darmach

    Résumé Résumé Plan Plan  
  • ·The Wnt signaling pathway in hepatocellular carcinoma: Regulatory mechanisms and therapeutic prospects

    Article :117508

    Shihui Ma, Guorui Meng, Tong Liu, Junqi You, Risheng He, Xudong Zhao, Yunfu Cui

    Résumé Résumé Plan Plan  
  • ·Targeting glucose metabolism for HPV-associated cervical cancer: A sweet poison

    Article :117519

    Yuan Tian, Songyang Zhang, Fushun Ni

    Résumé Résumé Plan Plan   
  • ·Electro-metabolic coupling in atrial fibrillation: A deeper understanding of the metabolic driver

    Article :117536

    Xinghua Qin, Lingyan Jin, Haoyu Gong, Qiangsun Zheng

    Résumé Résumé Plan Plan  
  • ·Effectiveness of platelet derivatives in neuropathic pain management: A systematic review

    Article :117507

    Eduardo Anitua, María Troya, Mohammad H. Alkhraisat

    Résumé Résumé Plan Plan  
  • ·Indole-3-carbinol and its main derivative 3,3′-diindolylmethane: Regulatory roles and therapeutic potential in liver diseases

    Article :117525

    Chao Tian, Shizhou Deng, Ming Yang, Baochen Bai, Yi Pan, Gangqiao Xie, Dongliang Zhao, Lai Wei

    Résumé Résumé Plan Plan  
  • ·Unveiling the immunogenicity of allogeneic mesenchymal stromal cells: Challenges and strategies for enhanced therapeutic efficacy

    Article :117537

    Yuanhui Li, Mengting Jin, Dongyang Guo, Shuang Shen, Kaining Lu, Ruolang Pan, Li Sun, Hongchen Zhang, Jianzhong Shao, Gang Pan

    Résumé Résumé Plan Plan  
  • ·Dissecting the roles of prosaposin as an emerging therapeutic target for tumors and its underlying mechanisms

    Article :117551

    Lirong Yan, Zhenpeng Wen, Yi Yang, Aoran Liu, Fang Li, Yuzhe Zhang, Chunjiao Yang, Yanke Li, Ye Zhang

    Résumé Résumé Plan Plan  
  • ·Advances in nanoparticle-based therapeutics for ischemic stroke: Enhancing drug delivery and efficacy

    Article :117564

    Peng Ji, Qingqing Xu, Jiahui Li, Zihan Wang, Wanyi Mao, Peng Yan

    Résumé Résumé Plan Plan  
  • ·An insight into allele-selective approaches to lowering mutant huntingtin protein for Huntington’s disease treatment

    Article :117557

    Jia-yuan Yao, Ting Liu, Xin-ru Hu, Hui Sheng, Zi-hao Chen, Hai-yang Zhao, Xiao-jia Li, Yang Wang, Liang Hao

    Résumé Résumé Plan Plan  
  • ·Advancements in nano drug delivery system for liver cancer therapy based on mitochondria-targeting

    Article :117520

    Lixia Chen, Yitian He, Jinshuai Lan, Zhe Li, Donghao Gu, Wenlong Nie, Tong Zhang, Yue Ding

    Résumé Résumé Plan Plan  
  • ·Advancements in nano-immunotherapy for gynecological cancers: A new frontier

    Article :117553

    Xiao Gu, Cuicui Wang

    Résumé Résumé Plan Plan  
  • ·Hidden potential of hydrazinecarboxamides (semicarbazides) as potential antimicrobial agents: A review

    Article :117556

    Martin Krátký, Neto-Honorius Houngbedji, Jarmila Vinšová

    Résumé Résumé Plan Plan  
  • ·Targeting ferroptosis in treating traumatic brain injury: Harnessing the power of traditional Chinese medicine

    Article :117555

    Zhongjie Sun, Xiao Zhang, Manrui Li, Qiuyun Yang, Xiao Xiao, Xiameng Chen, Weibo Liang

    Résumé Résumé Plan Plan  
  • ·The roles of lncRNAs in the development of drug resistance of oral cancers

    Article :117458

    Wenjing Wang, Yi Liu, Jianan Wu

    Résumé Résumé Plan Plan  
  • ·Pharmacological potential of natural medicine Astragali Radix in treating intestinal diseases

    Article :117580

    Xiunan Wei, Xiaohui Leng, Junwei Liang, Jiahui Liu, Lili Chi, Hualiang Deng, Dajuan Sun

    Résumé Résumé Plan Plan  
  • ·Targeted modulation of myeloid-derived suppressor cells in the tumor microenvironment: Implications for cancer therapy

    Article :117590

    Yafeng Qi, Liying Zhang, Yeyuan Liu, Yangyang Li, Yongqi Liu, Zhiming Zhang

    Résumé Résumé Plan Plan  
  • ·Bidirectional modulation of extracellular vesicle-autophagy axis in acute lung injury: Molecular mechanisms and therapeutic implications

    Article :117566

    Linqiang Tian, Jie Jin, Qianying Lu, Huajing Zhang, Sijia Tian, Feng Lai, Chuanchuan Liu, Yangfan Liang, Yujia Lu, Yanmei Zhao, Sanqiao Yao, Wenjie Ren

    Résumé Résumé Plan Plan  
  • ·Potential antitumor activity of triptolide and its derivatives: Focused on gynecological and breast cancers

    Article :117581

    Mengjie Li, Jiamiao Li, Qing Tang, Yongxia Zhu

    Résumé Résumé Plan Plan  
  • ·Recent breakthroughs in innovative elements, multidimensional enhancements, derived technologies, and novel applications of PROTACs

    Article :117584

    Si-Han Zhang, Na Zeng, Jin-Zhou Xu, Chen-Qian Liu, Meng-Yao Xu, Jian-Xuan Sun, Ye An, Xing-Yu Zhong, Lin-Tao Miao, Shao-Gang Wang, Qi-Dong Xia

    Résumé Résumé Plan Plan  
  • ·The potential role of transcription factor sterol regulatory element binding proteins (SREBPs) in Alzheimer's disease

    Article :117575

    Siyuan Liu, Xinzhu Li, Panpan Fan, Yujia Gu, Aizhu Yang, Weiyi Wang, Lijun Zhou, Huanhua Chen, Fangyuan Zheng, Junjie Lin, Zihua Xu, Qingchun Zhao

    Résumé Résumé Plan Plan  
  • ·Physiological and tumor-associated angiogenesis: Key factors and therapy targeting VEGF/VEGFR pathway

    Article :117585

    Patryk Lorenc, Agata Sikorska, Sara Molenda, Natalia Guzniczak, Hanna Dams-Kozlowska, Anna Florczak

    Résumé Résumé Plan Plan  
  • ·The regulatory role of mitotic catastrophe in hepatocellular carcinoma drug resistance mechanisms and its therapeutic potential

    Article :117598

    Jianwang Li, Xiaozhen Cheng, Denggao Huang, Ronghua Cui

    Résumé Résumé Plan Plan  
  • ·β-Klotho as novel therapeutic target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A narrative review

    Article :117608

    Marica Meroni, Paola Dongiovanni, Francesca Tiano, Roberto Piciotti, Anna Alisi, Nadia Panera

    Résumé Résumé Plan Plan  
  • ·Gas immnuo-nanomedicines fight cancers

    Article :117595

    Mengchi Sun, Tianye Wang, Yinmei Zhu, Feng Ling, Jingwen Bai, Chengwu Tang

    Résumé Résumé Plan Plan  

• Original Articles

  • ·Therapeutic efficiency of Tamoxifen/Orlistat nanocrystals against solid ehrlich carcinoma via targeting TXNIP/HIF1-α/MMP-9/P27 and BAX/Bcl2/P53 signaling pathways

    Article :117429

    Thanaa A. El-Masry, Maysa M.F. El-Nagar, Ghaleb Ali Oriquat, Badriyah S. Alotaibi, Hebatallah M. Saad, Enas I. El Zahaby, Hanaa A. Ibrahim

    Résumé Résumé Plan Plan  
  • ·Baicalin methyl ester prevents the LPS – induced mice intestinal barrier damage in vivo and in vitro via P65/TNF-α/MLCK/ZO-1 signal pathway

    Article :117417

    Mei Liang, Xinyi Sun, Mengru Guo, Huining Wu, Linlu Zhao, Jin Zhang, Jieyi He, Xingbin Ma, Zhichao Yu, Yanhong Yong, Ravi Gooneratne, Xianghong Ju, Xiaoxi Liu

    Résumé Résumé Plan Plan   
  • ·A natural acylphloroglucinol exerts anti-erythroleukemia effects via targeting STAT3 and p38-MAPK, and inhibiting PI3K/AKT/mTOR signaling pathway

    Article :117424

    Jing-Rui Song, Zhen-Peng Niu, Kun Yang, Li Wang, Yu-Bing Huang, Qing Rao, Hai-Yang Liu, Xiao-Jiang Hao, Yan-Mei Li

    Résumé Résumé Plan Plan   
  • ·Macrolide resistance outcomes after the Covid-19 pandemic: A one health approach investigation

    Article :117437

    Sarah O. Rodrigues, Felipe R. Santiago, Monique S. Silva, Alex Sandro G. Lima, Lidiane E. Godoy, Michel De Waard, Dalia Fouad, Gaber E. Batiha, Tamara L. Santos, Jorge P. Pagnossa

    Résumé Résumé Plan Plan   
  • ·Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice

    Article :117459

    Miriam Santos-Caballero, Makeya A. Hasoun, Miguel Á. Huerta, M. Carmen Ruiz-Cantero, Miguel Á. Tejada, María Robles-Funes, Eduardo Fernández-Segura, Francisco J. Cañizares, Rafael González-Cano, Enrique J. Cobos

    Résumé Résumé Plan Plan   
  • ·Exploration of potential antidiabetic and antioxidant components from the branches of Mitragyna diversifolia and possible mechanism

    Article :117450

    Jing Lu, Hanlei Wang, Xuelin Chen, Kun Zhang, Xia Zhao, Yunxue Xiao, Fengxian Yang, Mei Han, Wenyi Yuan, Yuling Guo, Yumei Zhang

    Résumé Résumé Plan Plan   
  • ·SIRT7 protects against liver fibrosis by suppressing stellate cell activation via TGF-β/SMAD2/3 pathway

    Article :117477

    Cong Ding, Bohao Liu, Tingzi Yu, Zhiqiang Wang, Jinying Peng, Yiying Gu, Zhuan Li

    Résumé Résumé Plan Plan   
  • ·6-Gingerol improves lipid metabolism disorders in skeletal muscle by regulating AdipoR1/AMPK signaling pathway

    Article :117462

    Ze Peng, Yan Zeng, Xin Zeng, Qi Tan, Qifeng He, Shang Wang, Jianwei Wang

    Résumé Résumé Plan Plan   
  • ·Triptolide-induced acute liver injury and its mechanism with estradiol in regulating macrophage-mediated inflammation and hepatocyte function

    Article :117481

    Xiaomeng Zhang, Zhiwen Cao, Li Li, Peipei Lu, Qi Geng, Lan Yan, Bin Liu, Lin Lin, Lulu Zhang, Changqi Shi, Yong Tan, Xiaojuan He, Li Li, Ning Zhao, Cheng Lu

    Résumé Résumé Plan Plan   
  • ·Niacin regulates glucose metabolism and osteogenic differentiation via the SIRT2-C/EBPβ-AREG signaling axis

    Article :117447

    Jinlong Ma, Xiang Li, Qiuyue Li, Zhenqian Sun, Yunhao You, Lu Zhang, Zhongjie Ji, Hongming Zhou, Qingju Zhang, Limin Wang, Hongliang Wang, Guangjun Jiao, Yunzhen Chen

    Résumé Résumé Plan Plan   
  • ·Christensenella minuta mitigates behavioral and cardiometabolic hallmarks of social defeat stress

    Article :117377

    A. Agusti, GV. Molina-Mendoza, M. Tamayo, V. Rossini, MC. Cenit, C. Frances-Cuesta, V. Tolosa-Enguis, EM. Gómez Del Pulgar, A. Flor-Duro, Y. Sanz

    Résumé Résumé Plan Plan   
  • ·Novel RGD-decorated micelles loaded with doxorubicin for targeted breast cancer chemotherapy

    Article :117460

    Xiang Tang, Dongxu Gao, Xuejie Liu, Junfeng Liu, Tong Chen, Jun He

    Résumé Résumé Plan Plan  
  • ·TMT-based proteomics reveals methylprotodioscin alleviates oxidative stress and inflammation via COX6C in myocardial infraction

    Article :117489

    Zhihui Xu, Tingyu Song, Xiufang Yang, Linhao Cong, Lianhong Yin, Youwei Xu, Xu Han, Meng Gao, Lina Xu

    Résumé Résumé Plan Plan   
  • ·Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile

    Article :117469

    Matthew Phanchana, Methinee Pipatthana, Tanaporn Phetruen, Pattanai Konpetch, Pattaneeya Prangthip, Phurt Harnvoravongchai, Chanakarn Sripong, Sombat Singhakaew, Sarawut Wongphayak, Surang Chankhamhaengdecha, Tavan Janvilisri

    Résumé Résumé Plan Plan   
  • ·Histamine H₃ receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection

    Article :117454

    Silvia Sgambellone, Mohammad A. Khanfar, Silvia Marri, Serafina Villano, Patrizia Nardini, Annika Frank, David Reiner-Link, Holger Stark, Laura Lucarini

    Résumé Résumé Plan Plan   
  • ·Effect of statins on mitochondrial function and contractile force in human skeletal and cardiac muscle

    Article :117492

    Tim Somers, Sailay Siddiqi, Margit C.M. Janssen, Wim J. Morshuis, Renee G.C. Maas, Jan W. Buikema, Petra H.H. van den Broek, Tom J.J. Schirris, Frans G.M. Russel

    Résumé Résumé Plan Plan   
  • ·Targeting mast cell activation alleviates anti-MHC I antibody and LPS-induced TRALI in mice by pharmacologically blocking the TLR3 and MAPK pathway

    Article :117456

    Xiaobin Fang, Tianjiao Song, Ling Zheng, Yueyi Weng, Fei Gao, Chunheng Mo, Xiaochun Zheng

    Résumé Résumé Plan Plan   
  • ·Design, synthesis and biological evaluation of dual inhibitors targeting AR/AR-Vs and PARP1 in castration resistant prostate cancer therapy

    Article :117485

    Si-Han Zhang, Yaowu Su, Mengzhu Zheng, Na Zeng, Jian-Xuan Sun, Jin-Zhou Xu, Chen-Qian Liu, Shao-Gang Wang, Yirong Zhou, Qi-Dong Xia

    Résumé Résumé Plan Plan   
  • ·Soybean Extract Ameliorates Lung Injury induced by Uranium Inhalation: An integrated strategy of network pharmacology, metabolomics, and transcriptomics

    Article :117451

    Xin Yang, Hongying Liang, Yufu Tang, Ruifeng Dong, Qimiao Liu, Wanqing Pang, Lixia Su, Xiaona Gu, Mengya Liu, Qingdong Wu, Xiangming Xue, Jingming Zhan

    Résumé Résumé Plan Plan   
  • ·PPARγ antagonism as a new tool for preventing or overcoming endocrine resistance in luminal A breast cancers

    Article :117461

    Cecilia Boretto, Giuliana Muzio, Riccardo Autelli

    Résumé Résumé Plan Plan   
  • ·Enhancing targeted therapy by combining PI3K and AKT inhibitors with or without cisplatin or vincristine in medulloblastoma cell lines in vitro

    Article :117500

    Monika Lukoseviciute, Emma Need, Madeleine Birgersson, Tina Dalianis, Ourania N. Kostopoulou

    Résumé Résumé Plan Plan   
  • ·In situ crosslinked injectable chondroitin sulfate hydrogel for preventing postoperative adhesion

    Article :117495

    Shijun Wang, Yunhe Zheng, Yanyao Gao, Jiangchuan He, Feng Lv, Yizhuo Bu, Kailai Liu, Yuchen Zhang, Jinpeng Wen, Lei Wang, Ke Wang, Xiqian Zhang

    Résumé Résumé Plan Plan   
  • ·Prostaglandin E₂ signaling through prostaglandin E receptor subtype 2 and Nurr1 induces fibroblast growth factor 23 production

    Article :117475

    Martina Feger, Katharina Hammerschmidt, Ilona Liesche, Steffen Rausch, Jana Alber, Michael Föller

    Résumé Résumé Plan Plan   
  • ·Unveiling the antitumor synergy between pazopanib and metformin on lung cancer through suppressing p-Akt/ NF-κB/ STAT3/ PD-L1 signal pathway

    Article :117468

    Fatma M. Abdallah, Asser I. Ghoneim, Mohammad M. Abd‑Alhaseeb, Ihab T. Abdel-Raheem, Maged W. Helmy

    Résumé Résumé Plan Plan   
  • ·FTH1P8 induces and transmits docetaxel resistance by inhibiting ferroptosis in prostate cancer

    Article :117472

    Junhong Lu, Qingrong Zou, Yang Li, Chuanwei Xiong, Lin Tao, Jiayuan Wu, Mei Qin, Jie Yang, Linhong He, Meichun Qin, Min Dong, Yingxin Li, Sisi Cao

    Résumé Résumé Plan Plan   
  • ·Mechanism of synergistic action of colistin with resveratrol and baicalin against mcr-1-positive Escherichia coli

    Article :117487

    Ping Cheng, Yingying Sun, Botao Wang, Shuying Liang, Yuqi Yang, Shixin Gui, Kai Zhang, Shaoqi Qu, Lin Li

    Résumé Résumé Plan Plan   
  • ·Empagliflozin attenuates hypoxia-induced heart failure of zebrafish embryos via influencing MMP13 expression

    Article :117453

    R. Huttunen, A.-M. Haapanen-Saaristo, A. Hjelt, A. Jokilammi, I Paatero, H. Järveläinen

    Résumé Résumé Plan Plan   
  • ·Effects of Vitamin D on tumor cell proliferation and migration, tumor initiation and anti-tumor immune response in head and neck squamous cell carcinomas

    Article :117497

    Lukas A. Brust, Maximilian Linxweiler, Jana Schnatmann, Jan-Philipp Kühn, Moritz Knebel, Felix L. Braun, Silke Wemmert, Michael D. Menger, Bernhard Schick, Michael F. Holick, Fengshen Kuo, Luc G.T. Morris, Sandrina Körner

    Résumé Résumé Plan Plan   
  • ·Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy

    Article :117510

    Desheng Li, Xiaoqing Yuan, Jianjun Ma, Tao Lu, Jinjin Zhang, Huan Liu, Guanqing Zhang, Yue Wang, Xiaohan Liu, Qiqiang Xie, Ling Zhou, Maolei Xu

    Résumé Résumé Plan Plan   
  • ·Sodium octanoate mediates GPR84-dependent and independent protection against sepsis-induced myocardial dysfunction

    Article :117455

    Yao Lin, Wenbin Zhang, Xiangkang Jiang, Chenghao Wu, Jingyuan Yang, Jiawei Tao, Ziwei Chen, Jiantao He, Ruojie Zhu, Huiming Zhong, Jinbo Zhang, Jiefeng Xu, Zhaocai Zhang, Mao Zhang

    Résumé Résumé Plan Plan   
  • ·Paclitaxel-resistance facilitates glycolytic metabolism via Hexokinase-2-regulated ABC and SLC transporter genes in ovarian clear cell carcinoma

    Article :117452

    Tsai-Yu Lin, Shin-Yuan Gu, Yi-Hui Lin, Jou-Ho Shih, Jiun-Han Lin, Teh-Ying Chou, Yu-Ching Lee, Shwu-Fen Chang, Yaw-Dong Lang

    Résumé Résumé Plan Plan   
  • ·Pre-treatment with notoginsenoside R1 from Panax notoginseng protects against high-altitude-induced pulmonary edema by inhibiting pyroptosis through the NLRP3/caspase-1/GSDMD pathway

    Article :117512

    Demei Huang, Yilan Wang, Caixia Pei, Xiu Zhang, Zherui Shen, Nan Jia, Sijing Zhao, Guang Li, Zhenxing Wang

    Résumé Résumé Plan Plan  
  • ·Rutaecarpine alleviates inflammation and fibrosis by targeting CK2α in diabetic nephropathy

    Article :117499

    Juan Chen, Zi-yun Hu, Yu Ma, Shan Jiang, Jiu-yu Yin, Yu-kai Wang, Yong-gui Wu, Xue-qi Liu

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  • ·Aspirin reduces Ponatinib-induced cardiovascular toxic phenotypes and death in zebrafish

    Article :117503

    Ruiqi Yu, Nana Ai, Chen Huang, Danni Wang, Chao Bian, Wei Ge, Cheong-Meng Chong

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  • ·Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitro

    Article :117517

    Nasim Shahhamzehei, Sara Abdelfatah, Hannah S. Schwarzer-Sperber, Kathrin Sutter, Rümeysa Yücer, Gerhard Bringmann, Roland Schwarzer, Thomas Efferth

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  • ·Modulation of chemotherapy-induced peripheral neuropathy by JZL195 through glia and the endocannabinoid system

    Article :117515

    Leejeong Kim, Guanghai Nan, Hee Young Kim, Myeounghoon Cha, Bae Hwan Lee

    Résumé Résumé Plan Plan   
  • ·Sea cucumber-derived extract can protect skin cells from oxidative DNA damage and mitochondrial degradation, and promote wound healing

    Article :117466

    Bismoy Mazumder, Meng Lu, Hassan Rahmoune, Ana Fernandez-Villegas, Edward Ward, Min Wang, Jiaoyan Ren, Yi Yu, Ting Zhang, Ming Liang, Wenzhi Li, Nino F. Läubli, Clemens F. Kaminski, Gabriele S. Kaminski Schierle

    Résumé Résumé Plan Plan   
  • ·N-acyl glycines produced by commensal bacteria potentiate GLP-1 secretion as GPCR ligands

    Article :117467

    Anna Drzazga, Przemysław Bernat, Adriana Nowak, Marcin Szustak, Eliza Korkus, Edyta Gendaszewska-Darmach, Maria Koziołkiewicz

    Résumé Résumé Plan Plan   
  • ·Adaptations in glutathione-based redox protein signaling pathways and alcohol drinking across species

    Article :117514

    Jacqueline S. Womersley, Clémence Obellianne, Audrey E. Padula, Marcelo F. Lopez, William C. Griffin, Lauren E. Ball, Stefano Berto, Kathleen A. Grant, Danyelle M. Townsend, Joachim D. Uys, Patrick J. Mulholland

    Résumé Résumé Plan Plan   
  • ·New peripherally-restricted CB1 receptor antagonists, PMG-505–010 and −013 ameliorate obesity-associated NAFLD and fibrosis

    Article :117501

    Hyekyung Yang, Miey Park, Ji Hye Lee, Bokyoung Kim, Chang Sang Moon, Suyeal Bae, Younghoon Kim, Hae-Jeung Lee, Cheol-Young Park

    Résumé Résumé Plan Plan   
  • ·Effect of recombinant CYP3A4 variants and interaction on imatinib metabolism in vitro

    Article :117511

    Jie Chen, Yingying Hu, Jinyu Hu, Zhize Ye, Qianmeng Lin, Jian-ping Cai, Guo-xin Hu, Ren-ai Xu

    Résumé Résumé Plan Plan  
  • ·APMCG-1 attenuates ischemic stroke injury by reducing oxidative stress and apoptosis and promoting angiogenesis via activating PI3K/AKT pathway

    Article :117506

    Xingyue He, Mingdian Wu, Likun Chen, Meijun Liu, Xuan Hu, Ying Meng, Hao Yue, Xiaoshan Yang, Peng Zheng, Yulin Dai

    Résumé Résumé Plan Plan  
  • ·Targeting CXCR2 ameliorated tacrolimus-induced nephrotoxicity by alleviating overactivation of PI3K/AKT/mTOR pathway and calcium overload

    Article :117526

    Xiao Chen, Ke Hu, Yue Zhang, Su-Mei He, Dong-Dong Wang

    Résumé Résumé Plan Plan  
  • ·Protective effects of lemon nanovesicles: evidence of the Nrf2/HO-1 pathway contribution from in vitro hepatocytes and in vivo high-fat diet-fed rats

    Article :117532

    Roberta Gasparro, Giuditta Gambino, Giulia Duca, Danila Di Majo, Valentina Di Liberto, Vincenza Tinnirello, Giulia Urone, Nicolò Ricciardi, Monica Frinchi, Nima Rabienezhad Ganji, Giuseppe Vergilio, Francesco Paolo Zummo, Francesca Rappa, Simona Fontana, Alice Conigliaro, Pierangelo Sardo, Giuseppe Ferraro, Riccardo Alessandro, Stefania Raimondo

    Résumé Résumé Plan Plan   
  • ·Silencing the glycerol-3-phosphate acyltransferase-1 gene in the liver of mice fed a high-fat diet, enhances insulin sensitivity and glucose metabolism by promoting fatty acid beta-oxidation

    Article :117531

    Piotr Zabielski, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Karolina Pogodzińska, Agnieszka U. Błachnio-Zabielska

    Résumé Résumé Plan Plan   
  • ·Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis

    Article :117521

    Qijin Lu, Jinyun Ma, Yan Zhao, Guiqing Ding, Yuanhua Wang, Xi Qiao, Xiaodong Cheng

    Résumé Résumé Plan Plan   
  • ·Cell membrane camouflaged Cu-doped mesoporous polydopamine for combined CT/PTT/CDT synergistic treatment of breast cancer

    Article :117539

    Di Meng, Shuoye Yang, Lin Ju, Jinpeng Wang, Yanan Yang, Lu Zhang, Lan Cui

    Résumé Résumé Plan Plan   
  • ·Microglia-mediated endothelial protection: the role of SHPL-49 in ischemic stroke

    Article :117530

    Yu Zhao, Pei Zhang, Jiange Zhang

    Résumé Résumé Plan Plan   
  • ·Epertinib counteracts multidrug resistance in cancer cells by antagonizing the drug efflux function of ABCB1 and ABCG2

    Article :117542

    Bing-Huan Lin, Yen-Ching Li, Megumi Murakami, Yu-Shan Wu, Yang-Hui Huang, Tai-Ho Hung, Suresh.V. Ambudkar, Chung-Pu Wu

    Résumé Résumé Plan Plan  
  • ·Gingerenone A induces ferroptosis in colorectal cancer via targeting suppression of SLC7A11 signaling pathway

    Article :117529

    Hongyu Xiao, Chen Chen, Xin Yuan, Limei Yang, Yun Zheng, Jin Yuan, Song Huang, Jian Liang, Shengliang Yuan, Meifen Li, Junyan Wang

    Résumé Résumé Plan Plan   
  • ·L-Cysteine mitigates ROS-induced apoptosis and neurocognitive deficits by protecting against endoplasmic reticulum stress and mitochondrial dysfunction in mouse neuronal cells

    Article :117538

    Shin Young Park, Ki Yun Kim, Dong Seol Gwak, Soon Young Shin, Do Youn Jun, Young Ho Kim

    Résumé Résumé Plan Plan   
  • ·Carnosic acid ameliorates postinflammatory hyperpigmentation by inhibiting inflammatory reaction and melanin deposition

    Article :117522

    Heyi Su, Fan Yang, Keyi Lu, Jiaxian Ma, Guangming Huo, Shengjie Li, Jianmei Li

    Résumé Résumé Plan Plan  
  • ·N-butanol extract of Broussonetia papyrifera (L.) L′Hér. ex Vent root bark alleviates atopic dermatitis by targeting E3 ubiquitin ligase WWP1 to promote NLRP3 degradation

    Article :117561

    Cheng Zeng, Liangkun Weng, Yuanming Song, Yihang Huang, Wenjing Xiang, Zhiming Ye, Can Yu, Zixuan Lai, Yuxuan Song, Huiwen Yang, Luyong Zhang, Bing Liu

    Résumé Résumé Plan Plan   
  • ·Oleanolic acid 28-O-β-D-glucopyranoside: A novel therapeutic agent against ulcerative colitis via anti-inflammatory, barrier-preservation, and gut microbiota-modulation

    Article :117534

    Caixia Wang, Hanlin Liu, Zhuoqiao Li, Qingya Yang, Qianyun Wang, Ting Yang, Daohao Tang, Cuizhu Wang, Jinping Liu

    Résumé Résumé Plan Plan   
  • ·Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by changing macrophage phenotypes and increasing UCP1 expression in vascular smooth muscle cells

    Article :117527

    Aneta Stachowicz, Anna Wiśniewska, Klaudia Czepiel, Bartosz Pomierny, Alicja Skórkowska, Beata Kuśnierz-Cabala, Marcin Surmiak, Katarzyna Kuś, Mark E. Wood, Roberta Torregrossa, Matthew Whiteman, Rafał Olszanecki

    Résumé Résumé Plan Plan   
  • ·Integration strategies involving 16S rDNA sequencing combined with untargeted metabolomics revealed the mechanism of Selaginella tamariscina (Beauv.) Spring in db/db diabetic mice

    Article :117546

    Pengli Guo, Mengnan Zeng, Yuhan Zhang, Ziyu Zhang, Yanxing Wu, Kaili Ye, Fangzhuo Chang, Yuanyuan Wang, Xiaoke Zheng, Weisheng Feng

    Résumé Résumé Plan Plan   
  • ·Intradermal administration of novel particulate Chlamydia trachomatis vaccine candidates drives protective immune responses

    Article :117563

    Dung T. Huynh, Emanuele Nolfi, Safia Guleed, Lobna Medfai, Natascha Wolf, Rienke F. Uijen, Marien I. de Jonge, Peter van Ulsen, Jes Dietrich, Joen Luirink, Alice J.A.M. Sijts, Wouter S.P. Jong

    Résumé Résumé Plan Plan   
  • ·Scoulerine: A natural isoquinoline alkaloid targeting SLC6A3 to treat RCC

    Article :117524

    Tianrui Qu, Yu Sun, Jingying Zhao, Nanqi Liu, Jianli Yang, Dantong Lyu, Wenjie Huang, Weizhen Zhan, Tao Li, Zichuan Yao, Rongbo Yan, Haiyan Zhang, Hong Hong, Liye Shi, Xin Meng, Bo Yin

    Résumé Résumé Plan Plan   
  • ·Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy

    Article :117547

    Peiqiang Liu, Xiaomin Wu, Hao Lv, Jingyu Huang, Tian Gu, Duo Liu, Yu Xu

    Résumé Résumé Plan Plan  
  • ·Verapamil attenuates myocardial ischemia/reperfusion injury by inhibiting apoptosis via activating the JAK2/STAT3 signaling pathway

    Article :117568

    Yang Zhao, Weiyi Huang, Fang Liu, Qiang Sun, Daifei Shen, Wenjun Fan, Danmei Huang, Yanmei Zhang, Fenfei Gao, Bin Wang

    Résumé Résumé Plan Plan   
  • ·Semaglutide ameliorates Alzheimer's disease and restores oxytocin in APP/PS1 mice and human brain organoid models

    Article :117540

    Yinbing Zhang, Cheng Tang, Yao He, Yingqian Zhang, Qinxi Li, Ting Zhang, Bangcheng Zhao, Aiping Tong, Qixing Zhong, Zhihui Zhong

    Résumé Résumé Plan Plan   
  • ·Cordycepin mitigates dextran sulfate sodium-induced colitis through improving gut microbiota composition and modulating Th1/Th2 and Th17/Treg balance

    Article :117394

    Zhilin Liu, Shaoxian Wu, Wenting Zhang, Hengwei Cui, Jingfeng Zhang, Xuan Yin, Xiao Zheng, Tao Shen, Hanjie Ying, Lujun Chen, Haitao Wang, Jingting Jiang

    Résumé Résumé Plan Plan   
  • ·Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3

    Article :117533

    Maitane Asensio, Oscar Briz, Elisa Herraez, Laura Perez-Silva, Ricardo Espinosa-Escudero, Diego Bueno-Sacristan, Ana Peleteiro-Vigil, Helen Hammer, Oliver Pötz, Onat Kadioglu, Jesus M. Banales, Maria L. Martinez-Chantar, Matias A. Avila, Rocio I.R. Macias, Thomas Efferth, Jose J.G. Marin, Elisa Lozano

    Résumé Résumé Plan Plan   
  • ·Farnesol ameliorates DSS-induced IBD by regulating inflammatory cytokines, repairing the intestinal barrier, reversing the gut microbiota imbalance, and influencing fecal metabolome in C57BL/6 mice

    Article :117518

    Ya Yuan, Dazuo Wu, Heping Chen, Zheng Ma, Xinyue Peng, Xiaodie Li, Chuchu Zhao, Linping Jiang, Jinping Liang, Weiwei Zhang, Juan Dai

    Résumé Résumé Plan Plan   
  • ·Dual-aptamer-decorated reduction-activated dimeric-prodrug nanoparticles for broad-spectrum treatment of leukemia

    Article :117543

    Shan Yang, Riming Wang, Mei Liu, Yanhong Lv, Hong Fu, Xiaochen Cao, Guogang Dong

    Résumé Résumé Plan Plan   
  • ·Inhalation of H₂/O₂ (66.7 %/33.3 %) mitigates depression-like behaviors in diabetes mellitus complicated with depression mice via suppressing inflammation and preventing hippocampal damage

    Article :117559

    Huaju Fan, Yanhua Shi, Haiqiang Liu, Xiaofei Zuo, Yanmei Yang, Hao Yin, Yanyan Li, Xianghui Wang, Li Liu, Fengjiao Wang, Huifang Han, Qianying Wu, Nana Yang, Yaohui Tang, Guohua Lu

    Résumé Résumé Plan Plan   
  • ·Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugs

    Article :117523

    Lukša Popović, Ben Brankatschk, Giulia Palladino, Moritz J. Rossner, Michael C. Wehr

    Résumé Résumé Plan Plan   
  • ·Simeprevir induces ferroptosis through β-TrCP/Nrf2/GPX4 axis in triple-negative breast cancer cells

    Article :117558

    Zhirong Lin, Zifei Liu, Xinyu Yang, Zhilong Pan, Yaxin Feng, Yunyi Zhang, Huiping Chen, Liyan Lao, Jianing Chen, Fujun Shi, Chang Gong, Wenfeng Zeng

    Résumé Résumé Plan Plan   
  • ·Astragaloside IV alleviates heatstroke brain injury and neuroinflammation in male mice by regulating microglial polarization via the PI3K/Akt signaling pathway

    Article :117545

    Zeze Wang, Zhen Luo, Yulong Tan, Genlin He, Ping Li, Xiaoqian Liu, Tingting Shen, Yishan Liu, Xuesen Yang, Xue Luo

    Résumé Résumé Plan Plan   
  • ·Metformin-mediated protection against doxorubicin-induced cardiotoxicity

    Article :117535

    Ming-Li Sun, Jun-Min Dong, Chen Liu, Pu Li, Chao Zhang, Jie Zhen, Wei Chen

    Résumé Résumé Plan Plan   
  • ·The colony-stimulating factor-1 receptor inhibitor edicotinib counteracts multidrug resistance in cancer cells by inhibiting ABCG2-mediated drug efflux

    Article :117554

    Yen-Ching Li, Yun-Chieh Lee, Megumi Murakami, Yang-Hui Huang, Tai-Ho Hung, Yu-Shan Wu, Suresh.V. Ambudkar, Chung-Pu Wu

    Résumé Résumé Plan Plan  
  • ·Nephroprotective and hepatoprotective effects of lemongrass essential oil and citral on diclofenac-induced toxicity in mice

    Article :117541

    Mohaddeseh Abouhosseini Tabari, Masoumeh Houshyar, Atefeh Araghi, Navideh Mirzakhani, Giuseppe Crescenzo, Roberta Cardone, Claudia Zizzadoro

    Résumé Résumé Plan Plan  
  • ·Agmatine attenuates the severity of immunometabolic disorders by suppressing macrophage polarization: an in vivo study using an ulcerative colitis mouse model

    Article :117549

    Suyue Zhang, Zhen Sun, Yajuan Li, Xinjian Du, Kun Qian, Le Yang, Guangyan Jia, Jiye Yin, Sha Liao, Zhe Zhou

    Résumé Résumé Plan Plan   
  • ·Synaptic vesicle protein 2-targeted doxorubicin-loaded liposome for effective neuroblastoma therapy

    Article :117548

    Yang Liu, Dongya Zhang, Miaomiao Kong, Yibin Wang, Huiyuan Mei, Chunxu Shan, Jianghui Meng, Yan Zou, Jiafu Wang

    Résumé Résumé Plan Plan   
  • ·VP3.15 reduces acute cerebellum damage after germinal matrix-intraventricular hemorrhage of the preterm newborn

    Article :117586

    Isabel Atienza-Navarro, Angel del Marco, Maria de los Angeles Garcia-Perez, Alvaro Raya-Marin, Carmen Gil, Ana Martinez, Isabel Benavente-Fernandez, Simon Lubian-Lopez, Monica Garcia-Alloza

    Résumé Résumé Plan Plan  
  • ·Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer

    Article :117550

    Caili Xu, Xiting Huang, Qinchao Hu, Wenjing Xue, Kaicheng Zhou, Xingxiu Li, Yanyang Nan, Dianwen Ju, Ziyu Wang, Xuyao Zhang

    Résumé Résumé Plan Plan  
  • ·Empagliflozin attenuating renal interstitial fibrosis in diabetic kidney disease by inhibiting lymphangiogenesis and lymphatic endothelial-to-mesenchymal transition via the VEGF-C/VEGFR3 pathway

    Article :117589

    Jiaan Huang, Yan Liu, Mengting Shi, Xiaoyun Zhang, Yan Zhong, Shuai Guo, Yun Ma, Limin Pan, Fan Yang, Yuehua Wang

    Résumé Résumé Plan Plan   
  • ·The beneficial effects of Akkermansia muciniphila and its derivatives on pulmonary fibrosis

    Article :117571

    Shahrbanoo Keshavarz aziziraftar, Romina Bahrami, Danial Hashemi, Arefeh Shahryari, Amitis Ramezani, Fatemeh Ashrafian, Seyed Davar Siadat

    Résumé Résumé Plan Plan  
  • ·The prognostic value of tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma: A systematic review and meta-analysis

    Article :117544

    Meri Torri, Adam Sandell, Ahmed Al-Samadi

    Résumé Résumé Plan Plan   
  • ·Buparlisib and ponatinib inhibit aggressiveness of cholangiocarcinoma cells via suppression of IRS1-related pathway by targeting oxidative stress resistance

    Article :117569

    Waleeporn Kaewlert, Chadamas Sakonsinsiri, Worachart Lert-itthiporn, Panupong Mahalapbutr, Saba Ali, Thanyada Rungrotmongkol, Apinya Jusakul, Napat Armartmuntree, Chawalit Pairojkul, Guofei Feng, Ning Ma, Somchai Pinlaor, Mariko Murata, Raynoo Thanan

    Résumé Résumé Plan Plan   
  • ·A novel synthetic compound, deferiprone–resveratrol hybrid (DFP-RVT), promotes hepatoprotective effects and ameliorates iron-induced oxidative stress in iron-overloaded β-thalassemic mice

    Article :117570

    Jin Li, Hataichanok Chuljerm, Kornvipa Settakorn, Honghong Xu, Yongmin Ma, Woranontee Korsieporn, Narisara Paradee, Somdet Srichairatanakool, Pimpisid Koonyosying

    Résumé Résumé Plan Plan  
  • ·Targeted breast cancer therapy using novel nanovesicle formulations of Olea europaea extract

    Article :117583

    María del Carmen Villegas-Aguilar, María de la Luz Cádiz-Gurrea, Andres Salumets, David Arráez-Román, Antonio Segura-Carretero, Alberto Sola-Leyva, María Paz Carrasco-Jiménez

    Résumé Résumé Plan Plan   
  • ·Calcium handling abnormalities increase arrhythmia susceptibility in DMSXL myotonic dystrophy type 1 mice

    Article :117562

    Michael Cupelli, Vamsi Krishna Murthy Ginjupalli, Jean-Baptiste Reisqs, Yvonne Sleiman, Nabil El-Sherif, Geneviève Gourdon, Jack Puymirat, Mohamed Chahine, Mohamed Boutjdir

    Résumé Résumé Plan Plan   
  • ·Combined dapagliflozin and roxadustat effectively protected heart and kidney against cardiorenal syndrome-induced damage in rodent through activation of cell stress-Nfr2/ARE signalings and stabilizing HIF-1α

    Article :117567

    Pei-Hsun Sung, Ya Yue, Yi-Ling Chen, John Y. Chiang, Ben-Chung Cheng, Chih-Chao Yang, Han-Tan Chai, Hon-Kan Yip

    Résumé Résumé Plan Plan   
  • ·Antimigratory effects of a new NF-κB inhibitor, (S)-b-salicyloylamino-a-exo-methylene-ƴ-butyrolactone, in 2D and 3D breast cancer models

    Article :117552

    Paola Poma, Salvatrice Rigogliuso, Manuela Labbozzetta, Francesco Carfì Pavia, Camilla Carbone, Jun Ma, Alessandra Cusimano, Monica Notarbartolo

    Résumé Résumé Plan Plan   
  • ·Melittin treatment suppressed malignant NSCLC progression through enhancing CTSB-mediated hyperautophagy

    Article :117573

    Yuhan Wang, Tailei Yuan, Longyue He, Jingjing Huang, Nodemsahajoel Wilfred, Wenhui Yang, Mingming Jin, Gang Huang, Changlian Lu

    Résumé Résumé Plan Plan  
  • ·Modulation of inflammatory mediators underlies the antitumor effect of the combination of morusin and docetaxel on prostate cancer cells

    Article :117572

    Sana A. Fadil, Dina A.I. Albadawi, Khalid Z. Alshali, Hossam M. Abdallah, Mona M. Saber

    Résumé Résumé Plan Plan   
  • ·Isoliquiritigenin alleviates SLC7A11-mediated efferocytosis inhibition to promote wounds healing in diabetes

    Article :117578

    Xiaokang Gong, Jinhong Cai, Wenbiao Zheng, Jiehe Huang, Tao Chen, Weijie Chen, Xin Zheng

    Résumé Résumé Plan Plan  
  • ·Developing a novel P-glycoprotein inhibitor and pairing it with oral paclitaxel liposomes for enhanced cancer therapy

    Article :117577

    Sikai Deng, Weiwei Li, Qiyu Chen, Jianqun Shao, Junbo Zhang, Yuji Wang, Yinghuan Li

    Résumé Résumé Plan Plan  
  • ·L-NRB alleviates amyotrophic lateral sclerosis by regulating P11-Htr4 signaling pathway

    Article :117588

    Yunfeng Pan, Xiao Sun, Yu Tian, Miao Yu, Yun Luo, Xiaobo Sun

    Résumé Résumé Plan Plan   
  • ·PAD inhibition downregulates the cellular fibrotic behavior of senescent myofibroblasts derived from dilated cardiomyopathy

    Article :117579

    Alia Sadiq, Justyna Fert-Bober

    Résumé Résumé Plan Plan   
  • ·Sodium bicarbonate potentiates the antitumor effects of Olaparib in ovarian cancer via cGMP/PKG-mediated ROS scavenging and M1 macrophage transformation

    Article :117509

    Xiao Li, Yaoqi Sun, Jing Guo, Yujie Cheng, Wei Lu, Weihong Yang, Lian Wang, Zhongping Cheng

    Résumé Résumé Plan Plan  
  • ·Fraxinellone protects against cardiac injury and decreases ventricular fibrillation susceptibility during myocardial ischemia-reperfusion

    Article :117560

    Rui Huang, Xing Zhong, Pusong Tang, Qingning Huang, Xin Chen, Lu Ye, Dan Luo, Yaqin Yang, Yuhua Lei

    Résumé Résumé Plan Plan   
  • ·Therapeutic oligonucleotide ASC1R shows excellent tolerability and remarkable efficacy in reducing SARS-CoV-2 mRNA levels in C57BL/6 mice

    Article :117587

    Veronika Nemethova, Petra Babiakova, Michal Selc, Kristina Jakic, Lucia Uhelska, Boglarka Teglasova, Peter Makovicky, Andrea Babelova, Filip Razga

    Résumé Résumé Plan Plan   
  • ·Expediting the development of robust 5-FU-resistant colorectal cancer models using innovative combined in vivo and in vitro strategies

    Article :117576

    Ming Shao, Yunran Gao, Xiling Xu, Jiyuan Shi, Zunyun Wang, Juan Du

    Résumé Résumé Plan Plan   
  • ·Native corn (Zea mays L., cv. ‘Elotes Occidentales’) polyphenols extract reduced total cholesterol and triglycerides levels, and decreased lipid accumulation in mice fed a high-fat diet

    Article :117610

    Sarah N. Lee-Martínez, Ivan Luzardo-Ocampo, Haydé A. Vergara-Castañeda, Jose F. Vasco-Leal, Marcela Gaytán-Martínez, M. Liceth Cuellar-Nuñez

    Résumé Résumé Plan Plan   
  • ·Cereblon mediates macrophage differentiation and microglial phagocytosis by regulating calpain protease activity

    Article :117606

    Liang Zhou, Qing Sun, Dan Cao

    Résumé Résumé Plan Plan   
  • ·Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification

    Article :117611

    Han Guo, Chenyang Li, Jiaojiao Zhao, Tianyuan Guo, Siruan Chen, Xia Qin, Kangsheng Zhu, Wei Zhang

    Résumé Résumé Plan Plan   
  • ·Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells

    Article :117605

    Nayanendu Saha, Sang Gyu Lee, Eeva-Christine Brockmann, M. Jason de la Cruz, Yehuda Goldgur, Rachelle P. Mendoza, Elisa de Stanchina, Tanzy M. Love, Josh Marvald, Yan Xu, Kai Xu, Juha P. Himanen, Urpo Lamminmäki, Darren Veach, Dimitar B. Nikolov

    Résumé Résumé Plan Plan   
  • ·Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis

    Article :117614

    Qian Yan, Ping Li, Shasha Liu, Yang Sun, Chen Chen, Junpeng Long, Yuting Lin, Jinping Liang, Hanlong Wang, Ling Zhang, Hongbin Wang, Huiqin Wang, Songwei Yang, Meiyu Lin, Xuan Liu, Jiao Yao, Zhifeng Tian, Naihong Chen, Yantao Yang, Qidi Ai

    Résumé Résumé Plan Plan  
  • ·RETRACTED: Acetate supplementation improves neurological outcomes by preventing hyperglycemia and suppressing Serpina3n expression in CA1 region after cardiac arrest and cardiopulmonary resuscitation

    Article :117615

    Fei Peng, Feiyu Long, Bowen Gao, Yu Liang

    Résumé Résumé
  • ·RETRACTED: Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction

    Article :117592

    Yu-Hsuan Chen, Yo-Cheng Chang, Wan-Ju Wu, Min Chen, Chih-Ching Yen, Ying-Wei Lan, Hsu-Chen Cheng, Chuan-Mu Chen

    Résumé Résumé
  • ·Apixaban trough concentrations in atrial fibrillation patients with reduced renal function

    Article :117613

    Fadiea Al-Aieshy, Mika Skeppholm, Jonas Fyrestam, Fredrik Johansson, Anton Pohanka, Rickard E. Malmström

    Résumé Résumé Plan Plan   
  • ·Oleocanthal mitigates CoCl₂-induced oxidative damage and apoptosis via regulating MAPK pathway in human retinal pigment epithelial cells

    Article :117582

    Ko-Chieh Huang, Yi-Fen Chiang, Mohamed Ali, Shih-Min Hsia

    Résumé Résumé Plan Plan   
  • ·The cardioprotective effects of Fruitflow® against Doxorubicin-induced toxicity in rat cardiomyoblast cells H9c2 (2−1) and high-fat diet-induced dyslipidemia and pathological alteration in cardiac tissue of Wistar Albino rats

    Article :117607

    Diptimayee Das, Ganesan Jothimani, Antara Banerjee, Asim K. Duttaroy, Surajit Pathak

    Résumé Résumé Plan Plan   
  • ·Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations

    Article :117603

    Meng Zhang, Mei-Ling She, Jun Chen, Xiao-Qi Zeng, Qing-Quan Xiong, Ying-Huan Cen, Jia-An Ye, Guo-Bin Qiu, Shu-Yi Yang, Guang-Hui Ren

    Résumé Résumé Plan Plan  
  • ·Novel [¹⁸F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography

    Article :117617

    Pragalath Sadasivam, Siddesh V. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy, Peter Cheng, Chin Zan Feng, David Green, Julian L. Goggi, Edward G. Robins, Ran Yan

    Résumé Résumé Plan Plan   
  • ·Liposomal formulation with thiazolic compounds against bacterial efflux pumps

    Article :117600

    Ray Silva de Almeida, Priscilla Ramos Freitas, Ana Carolina Justino de Araujo, Saulo Relison Tintino, Jaime Ribeiro-Filho, Gustavo Marinho Miranda, Gustavo Miguel Sigueira, Sheila Alves Gonçalves, Diogo Teixeira Carvalho, Thiago Belarmino de Souza, Laís Regina dos Santos Folquitto, Danielle Ferreira Dias, António Raposo, Ariana Saraiva, Heesup Han, Henrique Douglas Melo Coutinho

    Résumé Résumé Plan Plan  
  • ·Targeting hypoxia in combination with paclitaxel to enhance therapeutic efficacy in breast and ovarian cancer

    Article :117601

    Laura Svajda, Ivan Ranđelović, Sára Eszter Surguta, Marcell Baranyi, Mihály Cserepes, József Tóvári

    Résumé Résumé Plan Plan   
  • ·Metformin restores autophagic flux and mitochondrial function in late passage myoblast to impede age-related muscle loss

    Article :116981

    Sooyoon Bang, Dong-Eun Kim, Hee-Taik Kang, Jong Hun Lee

    Résumé Résumé Plan Plan  

• Short Communications

  • ·Therapeutic effect and molecular mechanism of the ultra-low molecule compound K on multiple myeloma

    Article :117440

    Young Eun Lee, Jin Young Kim, Hye Ran Kim, Myung Geun Shin

    Résumé Résumé Plan Plan   
  • ·Local anesthetic tetracaine hydrochloride induces pyroptosis via caspase-3/gasdermin E in uveal melanoma

    Article :117471

    Peng Yi, Ran Zhang, Zhengshan Qin, Xin Zhao, Chunyi Wu, Yajun Yu, Li Liu, Jianlong Zhou, Jianguo Feng

    Résumé Résumé Plan Plan   

• Corrigendum

  • ·Corrigendum to “Calcium ion delivery by microbubble-assisted sonoporation stimulates cell death in human gastrointestinal cancer cells” [Biomed. Pharmacother. 179 (2024) 117339]

    Article :117442

    Dawid Przystupski, Dagmara Baczyńska, Joanna Rossowska, Julita Kulbacka, Marek Ussowicz

     
  • ·Corrigendum to “Hominis Placenta modulates PTSD-like behaviors in SPSS-induced PTSD mice: Regulating energy metabolism and neuronal activity” [Biomed. Pharmacother. 178 (2024) 117243]

    Article :117443

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    Article :117618

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    Article :117622

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    Article :117626

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