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• • ·Editorial Board

    Page :i

    

• Review Articles

  • ·Telomerase activity and telomere on stem progeny senescence

    Page :9-17

    Balal Brazvan, Abbas Ebrahimi-Kalan, Kobra Velaei, Ahmad Mehdipour, Zeynab Aliyari serej, Ayyub Ebrahimi, Mohammad Ghorbani, Omid Cheraghi, Hojjatollah Nozad Charoudeh

    Résumé Résumé Plan Plan  
  • ·Cardio-supportive devices (VRD & DCC device) and patches for advanced heart failure: A review, summary of state of the art and future directions

    Page :41-54

    Muhammad Naveed, Lei Han, Ghulam Jilany Khan, Sufia Yasmeen, Reyaj Mikrani, Muhammad Abbas, Li Cunyu, Zhou Xiaohui

    Résumé Résumé Plan Plan  
  • ·Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations

    Page :107-114

    Xiao Zhang, Guigao Lin, Liming Tan, Jinming Li

    Résumé Résumé Plan Plan  
  • ·Central nervous system diseases and Scutellaria: a review of current mechanism studies

    Page :185-195

    Samira EghbaliFeriz, Akram Taleghani, Zahra Tayarani-Najaran

    Résumé Résumé Plan Plan  
  • ·Role of lncRNAs in the cancer development and progression and their regulation by various phytochemicals

    Page :242-248

    Baskaran Rathinasamy, Bharath Kumar Velmurugan

    Résumé Résumé Plan Plan  
  • ·Current approaches for the treatment of premature ovarian failure with stem cell therapy

    Page :254-262

    Golshan Sheikhansari, Leili Aghebati-Maleki, Mohammad Nouri, Farhad Jadidi-Niaragh, Mehdi Yousefi

    Résumé Résumé Plan Plan  
  • ·The role of nutrients in the pathogenesis and treatment of migraine headaches: Review

    Page :317-325

    Elyas Nattagh-Eshtivani, Mahmood Alizadeh Sani, Monireh Dahri, Faezeh Ghalichi, Abed Ghavami, Pishva Arjang, Ali Tarighat-Esfanjani

    Résumé Résumé Plan Plan  
  • ·Stem cell therapy in Asherman syndrome and thin endometrium: Stem cell- based therapy

    Page :333-343

    Ramyar Azizi, Leili Aghebati-Maleki, Mohammad Nouri, Faroogh Marofi, Sohrab Negargar, Mehdi Yousefi

    Résumé Résumé Plan Plan  
  • ·Estrogen: The necessary evil for human health, and ways to tame it

    Page :403-411

    Seema Patel, Ahmad Homaei, Akondi Butchi Raju, Biswa Ranjan Meher

    Résumé Résumé Plan Plan  
  • ·Chitooligosaccharide: An evaluation of physicochemical and biological properties with the proposition for determination of thermal degradation products

    Page :438-451

    Lucas Phil, Muhammad Naveed, Imran Shair Mohammad, Li Bo, Di Bin

    Résumé Résumé Plan Plan  
  • ·A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L.

    Page :575-586

    Ghazala Riaz, Rajni Chopra

    Résumé Résumé Plan Plan  
  • ·Arginine: Challenges and opportunities of this two-faced molecule in cancer therapy

    Page :594-601

    Mozhgan Jahani, Fatemeh Noroznezhad, Kamran Mansouri

    Résumé Résumé Plan Plan  
  • ·Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: Overview and current state of the art

    Page :608-617

    Hassan Mellatyar, Sona Talaei, Younes Pilehvar-Soltanahmadi, Abolfazl Barzegar, Abolfazl Akbarzadeh, Arman Shahabi, Mazyar Barekati-Mowahed, Nosratollah Zarghami

    Résumé Résumé Plan Plan  
  • ·Oncogenic long noncoding RNA MALAT1 and HCV-related hepatocellular carcinoma

    Page :653-669

    Eman A. Toraih, Alia Ellawindy, Salma Y. Fala, Essam Al Ageeli, Nawal S. Gouda, Manal S. Fawzy, Somaya Hosny

    Résumé Résumé Plan Plan   
  • ·Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases

    Page :689-698

    Abdoh Taleb, Khalil Ali Ahmad, Awais Ullah Ihsan, Jia Qu, Na Lin, Kamal Hezam, Nirmala Koju, Lei Hui, Ding Qilong

    Résumé Résumé Plan Plan  
  • ·Cancer chemotherapeutics in rheumatoid arthritis: A convoluted connection

    Page :894-911

    S. Jayashree, K. Nirekshana, Gunjan Guha, Dipita Bhakta-Guha

    Résumé Résumé Plan Plan  
  • ·The role of bevacizumab on tumour angiogenesis and in the management of gynaecological cancers: A review

    Page :1127-1144

    Dinesh Kumar Chellappan, Kun Hooi Leng, Lee Jia Jia, Nur Amirah Binti Abdul Aziz, Wong Chun Hoong, Yap Cheng Qian, Fam Yi Ling, Gwee Sing Wei, Tiong Ying, Jestin Chellian, Gaurav Gupta, Kamal Dua

    Résumé Résumé Plan Plan  
  • ·Tumor-derived extracellular vesicles in angiogenesis

    Page :1203-1208

    Wei Song, Dong Yan, Tianshu Wei, Qiang Liu, Xia Zhou, Ju Liu

    Résumé Résumé Plan Plan  

• Original Articles

  • ·Cortex Dictamni extracts inhibit over-proliferation and migration of rat airway smooth muscle cells via FAK/p38/Bcl-2 signaling pathway

    Page :1-8

    Tao Wei, Lei Liu, Xiaoying Zhou

    Résumé Résumé Plan Plan  
  • ·Medicinal mushroom Phellinus igniarius induced cell apoptosis in gastric cancer SGC-7901 through a mitochondria-dependent pathway

    Page :18-25

    Fei-Fei Wang, Chao Shi, Yue Yang, Yong Fang, Li Sheng, Ning Li

    Résumé Résumé Plan Plan  
  • ·Cav-1 deficiency promotes liver fibrosis in carbon tetrachloride (CCl₄)-induced mice by regulation of oxidative stress and inflammation responses

    Page :26-33

    De-Gang Ji, Yan Zhang, Song-Mei Yao, Xu-Jie Zhai, Li-Rong Zhang, Yao-Zhong Zhang, Hui Li

    Résumé Résumé Plan Plan   
  • ·MicroRNA-20b-5p inhibits platelet-derived growth factor-induced proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3

    Page :34-40

    Jin Tang, Lingying Luo

    Résumé Résumé Plan Plan   
  • ·Lung cancer targeted therapy: Folate and transferrin dual targeted, glutathione responsive nanocarriers for the delivery of cisplatin

    Page :55-63

    Sheng Tan, Guoxiang Wang

    Résumé Résumé Plan Plan  
  • ·Ziziphus spina-christi (L.) leaf extract alleviates myocardial and renal dysfunction associated with sepsis in mice

    Page :64-75

    Mohamed A. Dkhil, Rami B. Kassab, Saleh Al-Quraishy, Mohamed M. Abdel-Daim, Rafat Zrieq, Ahmed E. Abdel Moneim

    Résumé Résumé Plan Plan   
  • ·Protective effect of Lespedeza cuneata ethanol extract on Bisphenol A-induced testicular dysfunction in vivo and in vitro

    Page :76-85

    Bongkyun Park, Jeong Eun Kwon, Se Min Cho, Chang Won Kim, Da Eun Lee, Young Tae Koo, Sang Hun Lee, Hyun Myung Lee, Se Chan Kang

    Résumé Résumé Plan Plan  
  • ·MicRNA-320 facilitates the brain parenchyma injury via regulating IGF-1 during cerebral I/R injury in mice

    Page :86-93

    Lizhen Liang, Jun Wang, Yanrong Yuan, Yan Zhang, Huili Liu, Chunli Wu, Yongxing Yan

    Résumé Résumé Plan Plan  
  • ·Effect of metformin on estrogen and progesterone receptor-positive (MCF-7) and triple-negative (MDA-MB-231) breast cancer cells

    Page :94-101

    Inês Amaral, Cláudia Silva, Ana Correia-Branco, Fátima Martel

    Résumé Résumé Plan Plan  
  • ·Long noncoding RNA MINCR regulates cellular proliferation, migration, and invasion in hepatocellular carcinoma

    Page :102-106

    Jinyu Cao, Deyuan Zhang, Liangtao Zeng, Fanrong Liu

    Résumé Résumé Plan Plan  
  • ·Gefitinib inhibits retina angiogenesis by affecting VEGF signaling pathway

    Page :115-119

    Haitao Hu, Lanxiang Hao, Biao Yan, Xiumiao Li, Yunxi Zhu, Jin Yao, Guangji Wang, Qin Jiang

    Résumé Résumé Plan Plan  
  • ·Participation of the IKK-α/β complex in the inhibition of the TNF-α/NF-κB pathway by glycine: Possible involvement of a membrane receptor specific to adipocytes

    Page :120-131

    Erika Contreras-Nuñez, Gerardo Blancas-Flores, Miguel Cruz, Julio Cesar Almanza-Perez, Jaime H. Gomez-Zamudio, Jose Luis Ventura-Gallegosc, Alejandro Zentella-Dehesa, Ruben Roman-Ramos, Francisco Javier Alarcon-Aguilar

    Résumé Résumé Plan Plan  
  • ·Bioprospection of Eugenia brasiliensis, a Brazilian native fruit, as a source of anti-inflammatory and antibiofilm compounds

    Page :132-139

    Josy Goldoni Lazarini, Janaina de Cássia Orlandi Sardi, Marcelo Franchin, Bruno Dias Nani, Irlan Almeida Freires, Juliana Infante, Jonas Augusto Rizzato Paschoal, Severino Matias de Alencar, Pedro Luiz Rosalen

    Résumé Résumé Plan Plan  
  • ·Resveratrol regulates hyperglycemia-induced modulations in experimental diabetic animal model

    Page :140-146

    Kanwal Rehman, Kiran Saeed, Syeda Mehak Munawar, Muhammad Sajid Hamid Akash

    Résumé Résumé Plan Plan  
  • ·miR-424-5p regulates cell proliferation, migration and invasion by targeting doublecortin-like kinase 1 in basal-like breast cancer

    Page :147-152

    Jianling Wang, Shibing Wang, Jijun Zhou, Qian Qian

    Résumé Résumé Plan Plan  
  • ·MiR-34a-5p mediates sevoflurane preconditioning induced inhibition of hypoxia/reoxygenation injury through STX1A in cardiomyocytes

    Page :153-159

    Li Wenlan, Xia Zhongyuan, Lei Shaoqing, Zhan Liying, Zhao Bo, Liu Min

    Résumé Résumé Plan Plan  
  • ·Atorvastatin dose-dependently promotes mouse lung repair after emphysema induced by elastase

    Page :160-168

    Adriana Correa Melo, Isabella Cattani-Cavalieri, Marina Valente Barroso, Nicolas Quesnot, Lycia Brito Gitirana, Manuella Lanzetti, Samuel Santos Valença

    Résumé Résumé Plan Plan   
  • ·LncRNA CBR3-AS1 predicts unfavorable prognosis and promotes tumorigenesis in osteosarcoma

    Page :169-174

    Yunxing Zhang, Wang Meng, Hongxia Cui

    Résumé Résumé Plan Plan  
  • ·Quercetin attenuates zymosan-induced arthritis in mice

    Page :175-184

    Carla F.S. Guazelli, Larissa Staurengo-Ferrari, Ana C. Zarpelon, Felipe A. Pinho-Ribeiro, Kenji W. Ruiz-Miyazawa, Fabiana T.M.C. Vicentini, Josiane A. Vignoli, Doumit Camilios-Neto, Sandra R. Georgetti, Marcela M. Baracat, Rubia Casagrande, Waldiceu A. Verri

    Résumé Résumé Plan Plan   
  • ·Protective effects of phycocyanin on ischemia/reperfusion liver injuries

    Page :196-202

    Neyla Ben Gdara, Amel Belgacem, Ikram Khemiri, Safa Mannai, Lotfi Bitri

    Résumé Résumé Plan Plan  
  • ·MicroRNA-625-3p promotes the proliferation, migration and invasion of thyroid cancer cells by up-regulating astrocyte elevated gene 1

    Page :203-211

    Lei Fang, Dedi Kong, Wei Xu

    Résumé Résumé Plan Plan  
  • ·Panax quinquefolius saponin inhibits endoplasmic reticulum stress-mediated apoptosis and neurite injury and improves functional recovery in a rat spinal cord injury model

    Page :212-220

    Hai-Cheng Dou, Jun-Yu Chen, Tang-Fei Ran, Wei-Min Jiang

    Résumé Résumé Plan Plan  
  • ·The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer

    Page :221-229

    Hilal Gungor, Nevin Ilhan, Hatice Eroksuz

    Résumé Résumé Plan Plan  
  • ·Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells

    Page :230-241

    Laurence Bertier, Tim Hebbrecht, Elien Mettepenningen, Natasja De Wit, Olivier Zwaenepoel, Adriaan Verhelle, Jan Gettemans

    Résumé Résumé Plan Plan   
  • ·Trans-anethole prevents hypertension induced by chronic exposure to both restraint stress and nicotine in rats

    Page :249-253

    Eunhye Seo, Purum Kang, Geun Hee Seol

    Résumé Résumé Plan Plan  
  • ·Metformin inhibits glioma cells stemness and epithelial-mesenchymal transition via regulating YAP activity

    Page :263-270

    Xuesong Yuan, Wenfeng Wei, Qing Bao, Hongchun Chen, Peng Jin, Wenqing Jiang

    Résumé Résumé Plan Plan  
  • ·Silencing ZAP70 prevents HSP65-induced reverse cholesterol transport and NF-κB activation in T cells

    Page :271-277

    Jing Hu, Tiantian Luo, Dan Xi, Kai Guo, Lu Hu, Jinzhen Zhao, Si Chen, Zhigang Guo

    Résumé Résumé Plan Plan  
  • ·Epiisopiloturine, an imidazole alkaloid, reverses inflammation and lipid peroxidation parameters in the Crohn disease model induced by trinitrobenzenosulfonic acid in Wistar rats

    Page :278-285

    Lucas Rodrigues de Carvalho, Tarcisio Vieira de Brito, José Simião da C. Júnior, Genilson José Dias Júnior, Diva de Aguiar Magalhãres, Stefany Guimarães Sousa, Renan Oliveira Silva, Felipe Rodolfo Pereira da Silva, Daniel Fernando Pereira Vasconcelos, Leiz Maria Costa Véras, José Roberto de Sousa de Almeida Leite, Dainesy Santos Martins, Conceição da Silva Martins, Jefferson Soares de Oliveira, André Luiz dos Reis Barbosa

    Résumé Résumé Plan Plan  
  • ·MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer

    Page :286-294

    Manxin Xie, Ziyi Fu, Jianxiang Cao, Yuan Liu, Jie Wu, Qing Li, Yun Chen

    Résumé Résumé Plan Plan   
  • ·RETRACTED: Astragalus polysaccharide protects hypoxia-induced injury by up-regulation of miR-138 in rat neural stem cells

    Page :295-301

    Zebao Zheng, Bing Zhao

    
  • ·Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-κB signaling or PI3K/AKT/mTOR pathway

    Page :302-308

    Suxian Zhang, Tianyan Leng, Qin Zhang, Qinghua Zhao, Xiaofeng Nie, Lihua Yang

    Résumé Résumé Plan Plan  
  • ·Enhanced lipoxygenase/LTD4 signaling accounts for the exaggerated hypertensive and nephrotoxic effects of cyclosporine plus indomethacin in rats

    Page :309-316

    Maged W. Helmy, Mai M. Helmy, Mahmoud M. El-Mas

    Résumé Résumé Plan Plan  
  • ·Long noncoding RNA SNHG7 accelerates prostate cancer proliferation and cycle progression through cyclin D1 by sponging miR-503

    Page :326-332

    Honggang Qi, Bifeng Wen, Qihang Wu, Wei Cheng, Jiangyong Lou, Junjun Wei, Jianjun Huang, Xuping Yao, Guobin Weng

    Résumé Résumé Plan Plan  
  • ·Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity

    Page :344-353

    Jing Yang, Yue Sun, Fanxing Xu, Weiwei Liu, Toshihiko Hayashi, Satoshi Onodera, Shin-ichi Tashiro, Takashi Ikejima

    Résumé Résumé Plan Plan   
  • ·Experimental diabetes induced by streptozotocin in the desert gerbil, Gerbillus gerbillus, and the effects of short-term 20-hydroxyecdysone administration

    Page :354-361

    Aicha Mallek, Jamileh Movassat, Souad Ameddah, Junjun Liu, Nesrine Semiane, Ali Khalkhal, Yasmina Dahmani

    Résumé Résumé Plan Plan  
  • ·Linalyl acetate prevents olmesartan-induced intestinal hypermotility mediated by interference of the sympathetic inhibitory pathway in hypertensive rat

    Page :362-368

    Soonho Kwon, Yu Shan Hsieh, You Kyoung Shin, Purum Kang, Geun Hee Seol

    Résumé Résumé Plan Plan  
  • ·TNF-α contributes to postmenopausal osteoporosis by synergistically promoting RANKL-induced osteoclast formation

    Page :369-374

    Li Zha, Li He, Yijian Liang, Hui Qin, Bin Yu, Linli Chang, Li Xue

    Résumé Résumé Plan Plan  
  • ·Pretreatment with taurine prevented brain injury and exploratory behaviour associated with administration of anticancer drug cisplatin in rats

    Page :375-384

    Olatunde Owoeye, Isaac A. Adedara, Ebenezer O. Farombi

    Résumé Résumé Plan Plan  
  • ·Anti-arrhythmogenic and anti-inflammatory effects of troxerutin in ischemia/reperfusion injury of diabetic myocardium

    Page :385-391

    Moslem Najafi, Elham Noroozi, Aniseh Javadi, Reza Badalzadeh

    Résumé Résumé Plan Plan  
  • ·Umbelliferone prevents oxidative stress, inflammation and hematological alterations, and modulates glutamate-nitric oxide-cGMP signaling in hyperammonemic rats

    Page :392-402

    Mousa O. Germoush, Sarah I. Othman, Maha A. Al-Qaraawi, Hanan M. Al-Harbi, Omnia E. Hussein, Gadh Al-Basher, Mohammed F. Alotaibi, Hassan A. Elgebaly, Mansur A. Sandhu, Ahmed A. Allam, Ayman M. Mahmoud

    Résumé Résumé Plan Plan  
  • ·Sesquiterpenoids from the root of Panax Ginseng protect CCl₄–induced acute liver injury by anti-inflammatory and anti-oxidative capabilities in mice

    Page :412-419

    Weidong Wang, Shijie Wang, Jinping Liu, Enbo Cai, Hongyan Zhu, Zhongmei He, Yugang Gao, Pingya Li, Yan Zhao

    Résumé Résumé Plan Plan  
  • ·The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma

    Page :420-427

    Xian Lu, Guanqun Wo, Binghua Li, Chun Xu, Junhua Wu, Chunping Jiang, Jiwu Wei

    Résumé Résumé Plan Plan  
  • ·VS-5584 as a PI3K/mTOR inhibitor enhances apoptotic effects of subtoxic dose arsenic trioxide via inhibition of NF-κB activity in B cell precursor-acute lymphoblastic leukemia

    Page :428-437

    Bahareh Toosi, Farhad Zaker, Fatemeh Alikarami, Ahmad Kazemi, Majid Teremmahi Ardestanii

    Résumé Résumé Plan Plan  
  • ·LncRNA SNHG6 acts as a prognostic factor to regulate cell proliferation in glioma through targeting p21

    Page :452-457

    Gang Cai, Qing Zhu, Liqun Yuan, Qing Lan

    Résumé Résumé Plan Plan  
  • ·Molecular basis of vascular damage caused by cigarette smoke exposure and a new approach to the treatment: Alpha-linolenic acid

    Page :458-463

    Halil Mahir Kaplan, Yurdun Kuyucu, Sait Polat, Percin Pazarci, Arash Alizadeh Yegani, Ergin Şingirik, Peyman Ertuğ

    Résumé Résumé Plan Plan  
  • ·Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice

    Page :464-471

    Xixi Cheng, Huafeng Wang, Jinlai Yang, Yingnan Cheng, Dan Wang, Fengrui Yang, Yan Li, Dongmei Zhou, Yanxia Wang, Zhenyi Xue, Lijuan Zhang, Qi Zhang, Luhong Yang, Rongxin Zhang, Yurong Da

    Résumé Résumé Plan Plan  
  • ·Punicalagin ameliorates the elevation of plasma homocysteine, amyloid-β, TNF-α and apoptosis by advocating antioxidants and modulating apoptotic mediator proteins in brain

    Page :472-480

    Mohammed A. El-Missiry, Magda A. ElKomy, Azza I. Othman, Ali M. AbouEl-ezz

    Résumé Résumé Plan Plan  
  • ·The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D₄ receptor binding and toxicological assessment

    Page :481-493

    Fabiana Bettanin Costa, Alane P. Cortez, Renato Ivan de Ávila, Flávio S. de Carvalho, Wanessa M. Andrade, Andrezza F. da Cruz, Karinna B. Reis, Ricardo Menegatti, Luciano M. Lião, Luiz Antônio S. Romeiro, François Noël, Carlos Alberto M. Fraga, Eliezer J. Barreiro, Germán Sanz, Marcella F. Rodrigues, Boniek G. Vaz, Marize Campos Valadares

    Résumé Résumé Plan Plan   
  • ·Bu-shen-zhu-yun decoction promotes synthesis and secretion of FSHβ and LHβ in anterior pituitary cells in vitro

    Page :494-501

    Xiaofei Jiang, Huifang Zhou, Mingqing Shi, Boru Zhou, Bei Liu, Yizhen Yuan, Jinjun Shan, Jianya Xu, Tong Xie

    Résumé Résumé Plan Plan   
  • ·Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma

    Page :502-509

    Xinbing Zhu, Zhengzheng Li, Tongtong Li, Fei Long, Yuesheng Lv, Lei Liu, Xuefeng Liu, Qimin Zhan

    Résumé Résumé Plan Plan  
  • ·Zingerone ameliorates cisplatin‐induced ovarian and uterine toxicity via suppression of sex hormone imbalances, oxidative stress, inflammation and apoptosis in female wistar rats

    Page :517-530

    Erdal kaygusuzoglu, Cuneyt Caglayan, Fatih Mehmet Kandemir, Serkan Yıldırım, Sefa Kucukler, Mehmet Akif Kılınc, Yavuz Selim Saglam

    Résumé Résumé Plan Plan  
  • ·Enhanced expression of SRPK2 contributes to aggressive progression and metastasis in prostate cancer

    Page :531-538

    Yang jia Zhuo, Ze zhen Liu, Song Wan, Zhi duan Cai, Jian jiang Xie, Zhou da Cai, Sheng da Song, Yue ping Wan, Wei Hua, Wei de Zhong, Chin lee Wu

    Résumé Résumé Plan Plan  
  • ·Tea polysaccharide inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells and ameliorates ovariectomy-induced osteoporosis in rats

    Page :539-548

    Huanhuan Xu, Dan Yin, Titi Liu, Fei Chen, Yingli Chen, Xuanjun Wang, Jun Sheng

    Résumé Résumé Plan Plan  
  • ·LDR reverses DDP resistance in ovarian cancer cells by affecting ERCC-1, Bcl-2, Survivin and Caspase-3 expressions

    Page :549-554

    Xingyan Ju, Hongsheng Yu, Donghai Liang, Tao Jiang, Yuanwei Liu, Ling Chen, Qing Dong, Xiaoran Liu

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  • ·Evaluation of curcumin loaded chitosan/PEG blended PLGA nanoparticles for effective treatment of pancreatic cancer

    Page :555-566

    Geetanjali Arya, Manasi Das, Sanjeeb Kumar Sahoo

    Résumé Résumé Plan Plan  
  • ·Lobaplatin promotes radiosensitivity, induces apoptosis, attenuates cancer stemness and inhibits proliferation through PI3K/AKT pathway in esophageal squamous cell carcinoma

    Page :567-574

    Shupei Pan, Yuchen Sun, Donghu Sui, Tian Yang, Shenbo Fu, Jizhao Wang, Beina Hui, Ruxing Xi, Chenchen He, Xiaozhi Zhang

    Résumé Résumé Plan Plan   
  • ·Knockdown of HuR represses osteosarcoma cells migration, invasion and stemness through inhibition of YAP activation and increases susceptibility to chemotherapeutic agents

    Page :587-593

    Wei Xu, Chao Chen, Ruijun Xu, Yifan Li, Ruixi Hu, Zhikun Li, Xiaodong Zhu

    Résumé Résumé Plan Plan   
  • ·Overexpression of lncRNA DANCR positively affects progression of glioma via activating Wnt/β-catenin signaling

    Page :602-607

    Jun Li, Liang Zhou

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  • ·RETRACTED: Sanyang Xuedai enhances the radiosensitivity of human non-small cell lung cancer cells via increasing iNOS/NO production

    Page :618-625

    Li Wang, Yaoxiong Xia, Ting Chen, Yueqin Zeng, Lan Li, Yu Hou, Wenhui Li, Zhijie Liu

    Résumé Résumé
  • ·The mechanisms involved in miR-9 regulated apoptosis in cervical cancer by targeting FOXO3

    Page :626-632

    Haiyan Zhang, Zhen Zhang, Surong Wang, Shiqian Zhang, Junying Bi

    Résumé Résumé Plan Plan  
  • ·Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction

    Page :633-638

    Ning Liu, Yalin Zhang, Han Su, Jinrong Wang, Zuwang Liu, Juan Kong

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  • ·Increased expression of circRNA_102231 in lung cancer and its clinical significance

    Page :639-644

    Liang Zong, Qingchao Sun, Haiping Zhang, Zhixiang Chen, Yanchao Deng, Desheng Li, Liwei Zhang

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  • ·Penconazole alters redox status, cholinergic function and lung’s histoarchitecture of adult rats: Reversal effect of vitamin E

    Page :645-652

    Mariem Chaâbane, Awatef Elwej, Imen Ghorbel, Sabrine Chelly, Hela Mnif, Tahia Boudawara, Semia Ellouze Chaabouni, Najiba Zeghal, Nejla Soudani

    Résumé Résumé Plan Plan  
  • ·Inhibitory effect of sinigrin on adipocyte differentiation in 3T3-L1 cells: Involvement of AMPK and MAPK pathways

    Page :670-680

    Hee-Weon Lee, Dong-Kwon Rhee, Byung-Oh Kim, Suhkneung Pyo

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  • ·Apigenin enhances the antitumor effects of cetuximab in nasopharyngeal carcinoma by inhibiting EGFR signaling

    Page :681-688

    Wen-Jian Hu, Jing Liu, Lun-Kun Zhong, Jian Wang

    Résumé Résumé Plan Plan  
  • ·Oncosis-like cell death is induced by berberine through ERK1/2-mediated impairment of mitochondrial aerobic respiration in gliomas

    Page :699-710

    Yuxue Sun, Jing Yu, Xinrui Liu, Chaochao Zhang, Junguo Cao, Guihong Li, Xingxing Liu, Yong Chen, Haiyan Huang

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  • ·Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ

    Page :711-717

    Ji-Ru Zhang, Qing-Bo Lu, Wu-Bing Feng, Hui-Ping Wang, Zi-Han Tang, Han Cheng, Qiong Du, Yuan-Ben Wang, Ke-Xue Li, Hai-Jian Sun

    Résumé Résumé Plan Plan  
  • ·miR-566 functions as an oncogene and a potential biomarker for prognosis in renal cell carcinoma

    Page :718-727

    Xiang Pan, Jing Quan, Zuwei Li, Liwen Zhao, Liang Zhou, Xu Jinling, Xu Weijie, Xin Guan, Hang Li, Shangqi Yang, Yaoting Gui, Yongqing Lai

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  • ·Quercus dilatata Lindl. ex Royle ameliorates BPA induced hepatotoxicity in Sprague Dawley rats

    Page :728-738

    Syeda Tayyaba Batool Kazmi, Muhammad Majid, Sonia Maryam, Aymen Rahat, Madiha Ahmed, Muhammad Rashid Khan, Ihsan ul Haq

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  • ·Ebselen can Protect Male Reproductive Organs and Male Fertility from Manganese Toxicity: Structural and Bioanalytical Approach in a Rat Model

    Page :739-748

    Amany Tharwat Mohammed, Lamiaa L.M. Ebraheim, Mohamed M.M. Metwally

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  • ·LncRNA SNHG20 promotes cell proliferation and invasion via miR-140-5p-ADAM10 axis in cervical cancer

    Page :749-757

    Huimin Guo, Shenghua Yang, Shaoru Li, Mengting Yan, Li Li, Hongxia Zhang

    Résumé Résumé Plan Plan  
  • ·Ameliorating effects of tempol on methotrexate-induced liver injury in rats

    Page :758-764

    Neslihan Pınar, Mahir Kaplan, Tümay Özgür, Oğuzhan Özcan

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  • ·Submicron emulsion of cinnamaldehyde ameliorates bleomycin-induced idiopathic pulmonary fibrosis via inhibition of inflammation, oxidative stress and epithelial-mesenchymal transition

    Page :765-771

    Li Yan, Fan Song, Hua Li, Yao Li, Jie Li, Qiao-Yan He, Di Zhang, Fang Wang, Meng Zhang, Hang Zhao, Tian Feng, Ying-Yong Zhao, Si-Wang Wang

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  • ·The natural phenolic peperobtusin A induces apoptosis of lymphoma U937 cells via the Caspase dependent and p38 MAPK signaling pathways

    Page :772-781

    Liying Shi, Haihong Qin, Xudong Jin, Xiuxiu Yang, Xuan Lu, Huiguo Wang, Ruoyu Wang, Dayong Yu, Baomin Feng

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  • ·Concentration-dependent dual effects of silibinin on kanamycin-induced cells death in Staphylococcus aureus

    Page :782-791

    Jia-Yi Cai, Jian Li, Yong-Na Hou, Kai Ma, Guo-Dong Yao, Wei-Wei Liu, Toshihiko Hayashi, Kikuji Itoh, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima

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  • ·Garlic extract favorably modifies markers of endothelial function in obese patients –randomized double blind placebo-controlled nutritional intervention

    Page :792-797

    Monika Szulińska, Matylda Kręgielska-Narożna, Joanna Świątek, Paulina Styś, Barbara Kuźnar-Kamińska, Hieronim Jakubowski, Jarosław Walkowiak, Paweł Bogdański

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  • ·Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain, and behavioral alterations in mice offspring

    Page :798-811

    Gadh I. Al-Basher, Hanan Aljabal, Rafa S. Almeer, Ahmed A. Allam, Ayman M. Mahmoud

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  • ·Phytochemicals-induced hormesis protects Caenorhabditis elegans against α-synuclein protein aggregation and stress through modulating HSF-1 and SKN-1/Nrf2 signaling pathways

    Page :812-822

    Shanmugam Govindan, Mohankumar Amirthalingam, Kalaiselvi Duraisamy, Thiruppathi Govindhan, Nivitha Sundararaj, Sundararaj Palanisamy

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  • ·p-Coumaric acid mediated protection of H9c2 cells from Doxorubicin-induced cardiotoxicity: Involvement of augmented Nrf2 and autophagy

    Page :823-832

    Mary Chacko Sunitha, Radhakrishnan Dhanyakrishnan, Bhaskara PrakashKumar, Kottayath Govindan Nevin

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  • ·The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin ameliorates retinal endothelial cell dysfunction triggered by inflammation

    Page :833-838

    Andreia Gonçalves, Luísa Almeida, Ana Paula Silva, Carlos Fontes-Ribeiro, António F. Ambrósio, Armando Cristóvão, Rosa Fernandes

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  • ·NOS1 mediates AP1 nuclear translocation and inflammatory response

    Page :839-847

    Mansi Srivastava, Mirza S. Baig

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  • ·Peel flour of Passiflora edulis Var. Flavicarpa supplementation prevents the insulin resistance and hepatic steatosis induced by low-fructose-diet in young rats

    Page :848-854

    M.J. Goss, M.L.O. Nunes, I.D. Machado, L. Merlin, N.B. Macedo, A.M.O. Silva, T.M.B. Bresolin, J.R. Santin

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  • ·Dose- dependent ameliorative effects of quercetin and l-Carnitine against atrazine- induced reproductive toxicity in adult male Albino rats

    Page :855-864

    Rabie L. Abdel Aziz, Ahmed Abdel-Wahab, Fatma I. Abo El-Ela, Nour El-Houda Y. Hassan, El-Shaymaa El-Nahass, Marwa A. Ibrahim, Abdel-Tawab A.Y. Khalil

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  • ·Molecular mechanism of Poria cocos combined with oxaliplatin on the inhibition of epithelial-mesenchymal transition in gastric cancer cells

    Page :865-873

    Na Wang, Dengxiang Liu, Jun Guo, Yawei Sun, Ting Guo, Xiaoyan Zhu

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  • ·The protective roles of L-borneolum, D-borneolum and synthetic borneol in cerebral ischaemia via modulation of the neurovascular unit

    Page :874-883

    Taiwei Dong, Nian Chen, Xiao Ma, Jian Wang, Jing Wen, Qian Xie, Rong Ma

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  • ·The inhibitory effect of rosmarinic acid on overexpression of NCX1 and stretch- induced arrhythmias after acute myocardial infarction in rats

    Page :884-893

    Somayeh Javidanpour, Mahin Dianat, Mohammad Badavi, Seyyed Ali Mard

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  • ·Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin

    Page :912-921

    Miklós Poór, Gabriella Boda, Violetta Mohos, Mónika Kuzma, Mónika Bálint, Csaba Hetényi, Tímea Bencsik

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  • ·NF-κB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice

    Page :922-929

    Dongyu Liu, Xiaowei Huo, Li Gao, Juan Zhang, Hui Ni, Li Cao

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  • ·Diosmin and crocin alleviate nephropathy in metabolic syndrome rat model: Effect on oxidative stress and low grade inflammation

    Page :930-937

    Rania El-Fawal, Hassan M. El Fayoumi, Mona F. Mahmoud

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  • ·Human cytomegalovirus infection-induced autophagy was associated with the biological behavioral changes of human umbilical vein endothelial cell (HUVEC)

    Page :938-946

    Jun Zhao, Feng Zhong, Haiyang Yu, Zhiwu Chen, Mingli Wang, Jason Chen

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  • ·Cerebral ischemia induced inflammatory response and altered glutaminergic function mediated through brain AT₁ and not AT₂ receptor

    Page :947-958

    A. Justin, S. Divakar, M. Ramanathan

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  • ·Saponins from Panax notoginseng leaves improve the symptoms of aplastic anemia and aberrant immunity in mice

    Page :959-965

    Yanna Zhao, Xiaohua Sun, Xiaoling Yu, Ruilan Gao, Liming Yin

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  • ·Bergenia ciliata ameliorates streptozotocin-induced spatial memory deficits through dual cholinesterase inhibition and attenuation of oxidative stress in rats

    Page :966-980

    Priyal Barai, Nisith Raval, Sanjeev Acharya, Niyati Acharya

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  • ·MicroRNA-210 aggravates hypoxia-induced injury in cardiomyocyte H9c2 cells by targeting CXCR4

    Page :981-987

    Min Feng, Zongqing Li, Dong Wang, Fang Wang, Chenyan Wang, Chunfang Wang, Faming Ding

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  • ·RETRACTED: MicroRNA-361-5p inhibits papillary thyroid carcinoma progression by targeting ROCK1

    Page :988-995

    Rui Li, Bingfei Dong, Zhengmin Wang, Tao Jiang, Guang Chen

    
  • ·Up-regulation of miR-20a by HPV16 E6 exerts growth-promoting effects by targeting PDCD6 in cervical carcinoma cells

    Page :996-1002

    Xin Liu

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  • ·Baicalein inhibits growth of Epstein-Barr virus-positive nasopharyngeal carcinoma by repressing the activity of EBNA1 Q-promoter

    Page :1003-1014

    Yaqian Zhang, Huan Wang, Yu Liu, Chao Wang, Jingchao Wang, Cong Long, Wei Guo, Xiaoping Sun

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  • ·The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis

    Page :1015-1024

    Yuankun Zhai, Qingfeng Wang, Yingying Li, Jiawei Cui, Kun Feng, Xijian Kong, Cory J. Xian

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  • ·Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats

    Page :1025-1036

    Yupei Zhang, Kairui Tang, Yuanjun Deng, Runsen Chen, Shu Liang, Huijun Xie, Yifang He, Yanning Chen, Qinhe Yang

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  • ·Astragaloside IV inhibits cell proliferation of colorectal cancer cell lines through down-regulation of B7-H3

    Page :1037-1044

    Shuxia Wang, Jianguo Mou, Lansong Cui, Xingong Wang, Zhiqing Zhang

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  • ·Plantamajoside inhibits lipopolysaccharide-induced epithelial-mesenchymal transition through suppressing the NF-κB/IL-6 signaling in esophageal squamous cell carcinoma cells

    Page :1045-1051

    Xiaohui Li, Dong Chen, Mengfei Li, Xiang Gao, Gongning Shi, Hui Zhao

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  • ·Phytochemical and cytotoxic evaluation of Medicago monantha: In vivo protective potential in rats

    Page :1052-1063

    Muhammad Kamran, Muhammad Rashid Khan, Hizb Ullah Khan, Mazhar Abbas, Munawar Iqbal, Arif Nazir

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  • ·Induction of apoptosis, anti-proliferation, tumor-angiogenic suppression and down-regulation of Dalton’s Ascitic Lymphoma (DAL) induced tumorigenesis by poly-l-lysine: A mechanistic study

    Page :1064-1076

    Souvik Debnath, Avinaba Mukherjee, Saumen Karan, Manish Debnath, Tapan Kumar Chatterjee

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  • ·Tangeretin inhibits high glucose-induced extracellular matrix accumulation in human glomerular mesangial cells

    Page :1077-1083

    Fang Chen, Yali Ma, Zhiqiang Sun, Xiaoguang Zhu

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  • ·Balanites aegyptiaca ameliorates insulin secretion and decreases pancreatic apoptosis in diabetic rats: Role of SAPK/JNK pathway

    Page :1084-1091

    Kamel M.A. Hassanin, Mohamed O. Mahmoud, Hossam M. Hassan, Abdel-Razik H. Abdel-Razik, Lourin N. Aziz, Mostafa E. Rateb

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  • ·Xianyu decoction attenuates the inflammatory response of human lung bronchial epithelial cell

    Page :1092-1098

    Chenyi Yu, Qiangwei Xiang, Hailin Zhang

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  • ·Sodium butyrate abolishes the degradation of type II collagen in human chondrocytes

    Page :1099-1104

    Wang Bo, Juan Zhou, Kunzheng Wang

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  • ·Long noncoding RNA BDNF-AS is associated with clinical outcomes and has functional role in human prostate cancer

    Page :1105-1110

    Wensheng Li, Zhongling Dou, Shuguang We, Zhiyi Zhu, Dong Pan, Zhaohui Jia, Hui Liu, Xiaobin Wang, Guoqiang Yu

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  • ·Xihuang pill promotes apoptosis of Treg cells in the tumor microenvironment in 4T1 mouse breast cancer by upregulating MEKK1/SEK1/JNK1/AP-1 pathway

    Page :1111-1119

    Liang Su, Yiming Jiang, Yu Xu, Xinye Li, Wenbin Gao, Chunwei Xu, Changqian Zeng, Jie Song, Wencai Weng, Wenbo Liang

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  • ·Resveratrol improves uric acid-induced pancreatic β-cells injury and dysfunction through regulation of miR-126

    Page :1120-1126

    Ying Xin, Haiyan Zhang, Zhaotong Jia, Xiaoqian Ding, Yong Sun, Qiang Wang, Tao Xu

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  • ·Lycium chinense leaves extract ameliorates diabetic nephropathy by suppressing hyperglycemia mediated renal oxidative stress and inflammation

    Page :1145-1151

    Opeyemi Joshua Olatunji, Hongxia Chen, Yifeng Zhou

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  • ·Thymoquinone alleviates arsenic induced hippocampal toxicity and mitochondrial dysfunction by modulating mPTP in Wistar rats

    Page :1152-1160

    Fakiha Firdaus, Mohd. Faraz Zafeer, Mohammad Waseem, Rizwan Ullah, Masood Ahmad, Mohammad Afzal

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  • ·Antiviral effects of Ma Huang Tang against H1N1 influenza virus infection in vitro and in an ICR pneumonia mouse model

    Page :1161-1175

    Wenyang Wei, Haitong Wan, Xueqian Peng, Huifen Zhou, Yiyu Lu, Yu He

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  • ·Lx2-32c inhibits the formation of mammosphere from MDA-MB-231 cells and induces apoptosis involving in down-regulating FoxM1

    Page :1176-1181

    Pei Cai, Zuoqi Xiao, Tao Pan, Xiaoke Wen, Jianguo Cao, Bo Ouyang

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  • ·Depressor effect of the young leaves of Polygonum hydropiper Linn. in high-salt induced hypertensive mice

    Page :1182-1187

    Sankar Devarajan, Eiji Yahiro, Yoshinari Uehara, Rieko Kuroda, Yoshio Hirano, Kaori Nagata, Shinichiro Miura, Keijiro Saku, Hidenori Urata

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  • ·Hsa_circ_0071589 promotes carcinogenesis via the miR-600/EZH2 axis in colorectal cancer

    Page :1188-1194

    Wang Yong, Xuan Zhuoqi, Wang Baocheng, Zhang Dongsheng, Zhang Chuan, Sun Yueming

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  • ·MiR-338-5p promotes the growth and metastasis of malignant melanoma cells via targeting CD82

    Page :1195-1202

    Jianwen Long, Jing Luo, Xuwen Yin

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  • ·RETRACTED: Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis

    Page :1209-1220

    Fa-Bo Feng, Hai-Yan Qiu

    
  • ·Muscarinic receptors, nitric oxide formation and cyclooxygenase pathway involved in tracheal smooth muscle relaxant effect of hydro-ethanolic extract of Lavandula angustifolia flowers

    Page :1221-1228

    Farzaneh Naghdi, Zahra Gholamnezhad, Mohammad Hossein Boskabady, Morteza Bakhshesh

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• Short Communication

  • ·Ginkgetin ameliorates experimental atherosclerosis in rats

    Page :510-516

    Naqi Lian, Jing Tong, Wenwen Li, Jingzhen Wu, Yu Li

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