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• • ·Editorial Board

    Article :111600

    

• Review Articles

  • ·Flavonoids against the SARS-CoV-2 induced inflammatory storm

    Article :111430

    Alena Liskova, Marek Samec, Lenka Koklesova, Samson M. Samuel, Kevin Zhai, Raghad Khalid Al-Ishaq, Mariam Abotaleb, Vladimir Nosal, Karol Kajo, Milad Ashrafizadeh, Ali Zarrabi, Aranka Brockmueller, Mehdi Shakibaei, Peter Sabaka, Ioana Mozos, David Ullrich, Robert Prosecky, Giampiero La Rocca, Martin Caprnda, Dietrich Büsselberg, Luis Rodrigo, Peter Kruzliak, Peter Kubatka

    Résumé Résumé Plan Plan  
  • ·The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases

    Article :111428

    Ya-Shuo Feng, Zi-Xuan Tan, Lin-Yu Wu, Fang Dong, Feng Zhang

    Résumé Résumé Plan Plan  
  • ·The role of gut microbiota in tumorigenesis and treatment

    Article :111444

    Jia-Yi Xu, Min-Ting Liu, Tao Tao, Xiao Zhu, Fang-Qin Fei

    Résumé Résumé Plan Plan  
  • ·The role of H19 lncRNA in conferring chemoresistance in cancer cells

    Article :111447

    Soudeh Ghafouri-Fard, Hamed Shoorei, Zahra Bahroudi, Atefe Abak, Mohammad Taheri

    Résumé Résumé Plan Plan  
  • ·The metastasizing mechanisms of lung cancer: Recent advances and therapeutic challenges

    Article :111450

    Shimin Xie, Zhengguo Wu, Yi Qi, Binhua Wu, Xiao Zhu

    Résumé Résumé Plan Plan  
  • ·Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells

    Article :111425

    Robin Augustine, Pan Dan, Anwarul Hasan, Israa Magdi Khalaf, Parvathy Prasad, Kajal Ghosal, Carmine Gentile, Lana McClements, Pablo Maureira

    Résumé Résumé Plan Plan  
  • ·Terpenoids from Curcumae Rhizoma: Their anticancer effects and clinical uses on combination and versus drug therapies

    Article :111350

    Yi Chen, Zongping Zhu, Jiao Chen, Yongfeng Zheng, Boonjai Limsila, Meigui Lu, Tianhui Gao, Qingsong Yang, Chaomei Fu, Wan Liao

    Résumé Résumé Plan Plan  
  • ·CXCL8 chemokine in ulcerative colitis

    Article :111427

    Yunfei Zhu, Shihua Yang, Nan Zhao, Chuanguo Liu, Fayan Zhang, Yuting Guo, Huimin Liu

    Résumé Résumé Plan Plan  
  • ·Drug-herb interactions between Scutellaria baicalensis and pharmaceutical drugs: Insights from experimental studies, mechanistic actions to clinical applications

    Article :111445

    Xian Zhou, Ling Fu, Pengli Wang, Lan Yang, Xiaoshu Zhu, Chun Guang Li

    Résumé Résumé Plan Plan  
  • ·Research progress on the pharmacological effect and clinical application of Tongqiao Huoxue Decoction in the treatment of ischaemic stroke

    Article :111460

    Qiang Zhang, Lijuan Zhang, Yu Liu, Xu Tian, Xiuyang Li, Bingbing Han, Yanan Zhang, Zhichun Wu, Huayun Yu, Haijun Zhao, Shijun Wang, Ke Ma, Yuan Wang

    Résumé Résumé Plan Plan   
  • ·Mechanism and application of metformin in kidney diseases: An update

    Article :111454

    Anni Song, Chun Zhang, Xianfang Meng

    Résumé Résumé Plan Plan  
  • ·Effect and mechanism of berberine against polycystic ovary syndrome

    Article :111468

    Si-wei Zhang, Jing Zhou, Hans-Jürgen Gober, Wing Ting Leung, Ling Wang

    Résumé Résumé Plan Plan  
  • ·Interaction between non-coding RNAs and JNK in human disorders

    Article :111497

    Soudeh Ghafouri-Fard, Atefe Abak, Mahdi Mohaqiq, Hamed Shoorei, Mohammad Taheri

    Résumé Résumé Plan Plan  
  • ·Intestinal ischemic reperfusion injury: Recommended rats model and comprehensive review for protective strategies

    Article :111482

    Jun Wang, Wentong Zhang, Guosheng Wu

    Résumé Résumé Plan Plan  
  • ·The interaction between miRNAs/lncRNAs and Notch pathway in human disorders

    Article :111496

    Soudeh Ghafouri-Fard, Mark C. Glassy, Atefe Abak, Bashdar Mahmud Hussen, Vahid Niazi, Mohammad Taheri

    Résumé Résumé Plan Plan  
  • ·Anti-inflammatory effects of thymoquinone and its protective effects against several diseases

    Article :111492

    Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Saeed Samarghandian

    Résumé Résumé Plan Plan  
  • ·CISD2 plays a role in age-related diseases and cancer

    Article :111472

    Hai-Yang Liao, Bei Liao, Hai-Hong Zhang

    Résumé Résumé Plan Plan  
  • ·Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential

    Article :111511

    Shahid Ali Rajput, Xiu-qi Wang, Hui-Chao Yan

    Résumé Résumé Plan Plan  
  • ·Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies

    Article :111495

    Nancy Y. Guerrero-Pepinosa, María C. Cardona-Trujillo, Sandra C. Garzón-Castaño, Luz Angela Veloza, Juan C. Sepúlveda-Arias

    Résumé Résumé Plan Plan  
  • ·The interaction between miRNAs/lncRNAs and nuclear factor-κB (NF-κB) in human disorders

    Article :111519

    Soudeh Ghafouri-Fard, Afete Abak, Faranak Fattahi, Bashdar M. Hussen, Zahra Bahroudi, Hamed Shoorei, Mohammad Taheri

    Résumé Résumé Plan Plan  
  • ·Human gene therapy: A scientometric analysis

    Article :111510

    Wuyuan Zhou, Xiang Wang

    Résumé Résumé Plan Plan  
  • ·Protein phase separation and its role in chromatin organization and diseases

    Article :111520

    Jiaqi Li, Yao Zhang, Xi Chen, Lijuan Ma, Pilong Li, Haijie Yu

    Résumé Résumé Plan Plan   
  • ·MicroRNA: A signature for cancer progression

    Article :111528

    Bashdar Mahmud Hussen, Hazha Jamal Hidayat, Abbas Salihi, Dana K. Sabir, Mohammad Taheri, Soudeh Ghafouri-Fard

    Résumé Résumé Plan Plan  
  • ·The emerging role of KIAA1199 in cancer development and therapy

    Article :111507

    Jingmei Liu, Wei Yan, Ping Han, Dean Tian

    Résumé Résumé Plan Plan  
  • ·Physiological and pathophysiological roles of acidic mammalian chitinase (CHIA) in multiple organs

    Article :111465

    Chunli Hu, Zhiyuan Ma, Jiaxing Zhu, Yi Fan, Biguang Tuo, Taolang Li, Xuemei Liu

    Résumé Résumé Plan Plan  
  • ·Therapeutic and diagnostic relevance of Crispr technology

    Article :111487

    Ibtissem El ouar, Abdelhamid Djekoun

    Résumé Résumé Plan Plan  
  • ·Potential therapeutic agents to COVID-19: An update review on antiviral therapy, immunotherapy, and cell therapy

    Article :111518

    Mona Sadat Mirtaleb, Amir Hossein Mirtaleb, Hassan Nosrati, Jalal Heshmatnia, Reza Falak, Reza Zolfaghari Emameh

    Résumé Résumé Plan Plan  
  • ·Exosomes in hepatocellular carcinoma microenvironment and their potential clinical application value

    Article :111529

    Risheng He, Zhongrui Wang, Wenguang Shi, Liang Yu, Haoming Xia, Ziyue Huang, Shuqiang Liu, Xudong Zhao, Yi Xu, Judy Wai Ping Yam, Yunfu Cui

    Résumé Résumé Plan Plan  
  • ·Natural compounds protect the skin from airborne particulate matter by attenuating oxidative stress

    Article :111534

    Ping Diao, Hailun He, Jie Tang, Lidan Xiong, Li Li

    Résumé Résumé Plan Plan  
  • ·Emerging impact of quercetin in the treatment of prostate cancer

    Article :111548

    Soudeh Ghafouri-Fard, Farnaz Aghazadeh Shabestari, Saba Vaezi, Atefe Abak, Hamed Shoorei, Arash Karimi, Mohammad Taheri, Abbas Basiri

    Résumé Résumé Plan Plan  
  • ·Investigating into anti-cancer potential of lycopene: Molecular targets

    Article :111546

    Wang Jia Qi, Wang Shi Sheng, Chu Peng, Ma Xiaodong, Tang Ze Yao

    Résumé Résumé Plan Plan  
  • ·Identification of FDA approved drugs against SARS-CoV-2 RNA dependent RNA polymerase (RdRp) and 3-chymotrypsin-like protease (3CLpro), drug repurposing approach

    Article :111544

    Zahra Molavi, Sara Razi, Seyed Amir Mirmotalebisohi, Amirjafar Adibi, Marzieh Sameni, Farshid Karami, Vahid Niazi, Zahra Niknam, Morteza Aliashrafi, Mohammad Taheri, Soudeh Ghafouri-Fard, Shabnam Jeibouei, Soodeh Mahdian, Hakimeh Zali, Mohammad Mehdi Ranjbar, Mohsen Yazdani

    Résumé Résumé Plan Plan   

• Original Articles

  • ·RETRACTED: Pharmacological evaluation of continentalic acid for antidiabetic potential

    Article :111411

    Iqra Liaquat, Arif-ullah Khan, Salman Khan

    
  • ·Suppression of uric acid generation and blockade of glutathione dysregulation by L-arginine ameliorates dichlorvos-induced oxidative hepatorenal damage in rats

    Article :111443

    W.A. Saka, R.E. Akhigbe, A.O. Abidoye, O.S. Dare, A.O. Adekunle

    Résumé Résumé Plan Plan   
  • ·Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease

    Article :111442

    Qiu-Ling Chen, Hao-Ran Yin, Qing-Yu He, Ying Wang

    Résumé Résumé Plan Plan  
  • ·Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury

    Article :111441

    Song Yang, Ting Hu, He Liu, Ya-li Lv, Wen Zhang, Han Li, Lingling Xuan, Li-li Gong, Li-hong Liu

    Résumé Résumé Plan Plan   
  • ·Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring

    Article :111440

    Hossein Rezazadeh, Mohammad Reza Sharifi, Mohmmadreza Sharifi, Nepton Soltani

    Résumé Résumé Plan Plan  
  • ·Epilobium angustifolium L. extract with high content in oenothein B on benign prostatic hyperplasia: A monocentric, randomized, double-blind, placebo-controlled clinical trial

    Article :111414

    Cristina Esposito, Cristina Santarcangelo, Raffaello Masselli, Giuseppe Buonomo, Giovanna Nicotra, Violetta Insolia, Maria D'Avino, Giuseppe Caruso, Antonio Riccardo Buonomo, Roberto Sacchi, Eduardo Sommella, Pietro Campiglia, Gian Carlo Tenore, Maria Daglia

    Résumé Résumé Plan Plan  
  • ·Augmentation of anti-proliferative, pro-apoptotic and oxidant profiles induced by piceatannol in human breast carcinoma MCF-7 cells using zein nanostructures

    Article :111409

    Mardi M. Algandaby, Majid M. Al-Sawahli

    Résumé Résumé Plan Plan  
  • ·PD-L1 silencing inhibits triple-negative breast cancer development and upregulates T-cell-induced pro-inflammatory cytokines

    Article :111436

    Parisa Lotfinejad, Tohid Kazemi, Sahar Safaei, Mohammad Amini, Elmira Roshani asl, Elham Baghbani, Siamak Sandoghchian Shotorbani, Farhad Jadidi Niaragh, Afshin Derakhshani, Mahdi Abdoli Shadbad, Nicola Silvestris, Behzad Baradaran

    Résumé Résumé Plan Plan  
  • ·OMA1520 and OMA1774, novel 1,2,4-triazole bearing analogs of combretastatin A-4, inhibit hepatocellular carcinoma: Histological and immunohistochemical studies

    Article :111417

    Amany E. Nofal, Ibrahim M. Shatla, Dalia A. Abdelhafeez, Muhamad Mustafa, Omar M. Aly

    Résumé Résumé Plan Plan   
  • ·Plasmodium infection inhibits triple negative 4T1 breast cancer potentially through induction of CD8⁺ T cell-mediated antitumor responses in mice

    Article :111406

    Jianhua Pan, Meng Ma, Li Qin, Zhongkui Kang, Dickson Adah, Zhu Tao, Xiaofen Li, Linglin Dai, Siting Zhao, Xiaoping Chen, Qin Zhou

    Résumé Résumé Plan Plan   
  • ·Phloroglucinol and dieckol isolated from Ecklonia cava suppress impaired diabetic angiogenesis; A study of in-vitro and in-vivo

    Article :111431

    Jin Hwang, Hye-Won Yang, Yu An Lu, Jun-Geon Je, Hyo-Geun Lee, K.H.N. Fernando, You-Jin Jeon, BoMi Ryu

    Résumé Résumé Plan Plan  
  • ·Total glucosides of paeony protects THP-1 macrophages against monosodium urate-induced inflammation via MALAT1/miR-876-5p/NLRP3 signaling cascade in gouty arthritis

    Article :111413

    Qingliang Meng, Wanting Meng, Hua Bian, Fuzeng Zheng, Huimin Gu, Ruiting Zuo, Xiyun Miao, Zipeng Zhou, Liying Wang, Zhike Wen, Junfu Ma, Xiao Su

    Résumé Résumé Plan Plan  
  • ·Antioxidative and antidiabetic effects of Capparis spinosa fruit extract on high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats

    Article :111391

    Shahabaddin Assadi, Sayed Mohammad Shafiee, Mehran Erfani, Masoumeh Akmali

    Résumé Résumé Plan Plan  
  • ·Monitoring topiramate concentrations at delivery and during lactation

    Article :111446

    Ivana Kacirova, Milan Grundmann, Hana Brozmanova, Blanka Koristkova

    Résumé Résumé Plan Plan  
  • ·Allyl Methyl Sulfide Preserved Pressure Overload-Induced Heart Failure Via Modulation of Mitochondrial Function

    Article :111316

    Soheb Anwar Mohammed, Bugga Paramesha, Himanshu Meghwani, Maramreddy Prasanna Kumar Reddy, Sudheer Kumar Arava, Sanjay Kumar Banerjee

    Résumé Résumé Plan Plan  
  • ·Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats’ brain

    Article :111458

    Sameh M. Farouk, Fatma A. Gad, Rafa Almeer, Mohamed M. Abdel-Daim, Mahmoud A. Emam

    Résumé Résumé Plan Plan  
  • ·Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection

    Article :111437

    Justin Fortune Creeden, Ali Sajid Imami, Hunter M. Eby, Cassidy Gillman, Kathryn N. Becker, Jim Reigle, Elissar Andari, Zhixing K. Pan, Sinead M. O’Donovan, Robert E. McCullumsmith, Cheryl B. McCullumsmith

    Résumé Résumé Plan Plan   
  • ·Curcumin suppresses the malignancy of non-small cell lung cancer by modulating the circ-PRKCA/miR-384/ITGB1 pathway

    Article :111439

    Xiaoqing Xu, Xinyue Zhang, Yang Zhang, Zhipeng Wang

    Résumé Résumé Plan Plan   
  • ·Antiviral activity of oleandrin and a defined extract of Nerium oleander against SARS-CoV-2

    Article :111457

    Kenneth S. Plante, Varun Dwivedi, Jessica A. Plante, Diana Fernandez, Divya Mirchandani, Nathen Bopp, Patricia V. Aguilar, Jun-Gyu Park, Paula Pino Tamayo, Jennifer Delgado, Vinay Shivanna, Jordi B. Torrelles, Luis Martinez-Sobrido, Rick Matos, Scott C. Weaver, K. Jagannadha Sastry, Robert A. Newman

    Résumé Résumé Plan Plan  
  • ·Exploring the mechanism of PingTang No.5 capsule on nonalcoholic fatty liver disease through network pharmacology and experimental validation

    Article :111408

    Tzu-Chieh Hung, Nengjiang Zhao, Caoxin Huang, Suhuan Liu, Tao Liu, Wenfang Huang, Xiangbin Xu, Zhi-Liang Ji, Shuyu Yang

    Résumé Résumé Plan Plan   
  • ·Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells

    Article :111452

    Jonna Tenhunen, Tomáš Kučera, Marjo Huovinen, Jenni Küblbeck, Egils Bisenieks, Brigita Vigante, Zaiga Ogle, Gunars Duburs, Martin Doležal, Ruin Moaddel, Maija Lahtela-Kakkonen, Minna Rahnasto-Rilla

    Résumé Résumé Plan Plan   
  • ·A global integrated analysis of UNC5C down-regulation in cancers: insights from mechanism and combined treatment strategy

    Article :111355

    Haotian Xing, Pinying Wang, Shuangjie Liu, Siyang Jing, Jiaxing Lin, Jieping Yang, Yuyan Zhu, Meng Yu

    Résumé Résumé Plan Plan   
  • ·ClC-3 promotes paclitaxel resistance via modulating tubulins polymerization in ovarian cancer cells

    Article :111407

    Jiezhu Feng, Zihan Peng, Lvfen Gao, Xiurou Yang, Zele Sun, Xiuying Hou, Enze Li, Linyan Zhu, Haifeng Yang

    Résumé Résumé Plan Plan  
  • ·Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway

    Article :111421

    Jianping Wang, Ting Li, Haiying Cai, Liangyan Jin, Run Li, Letian Shan, Wei Cai, Jianping Jiang

    Résumé Résumé Plan Plan  
  • ·Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes

    Article :111459

    Zelma Faisal, Violetta Mohos, Eszter Fliszár-Nyúl, Kateřina Valentová, Kristýna Káňová, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór

    Résumé Résumé Plan Plan   
  • ·Brivaracetam prevents astroglial l-glutamate release associated with hemichannel through modulation of synaptic vesicle protein

    Article :111462

    Motohiro Okada, Kouji Fukuyama, Takashi Shiroyama, Yuto Ueda

    Résumé Résumé Plan Plan  
  • ·Hibiscus sabdariffa L. calyx extract prevents the adipogenesis of 3T3-L1 adipocytes, and obesity-related insulin resistance in high-fat diet-induced obese rats

    Article :111438

    Benjarat Janson, Janjira Prasomthong, Wachirawadee Malakul, Tantip Boonsong, Sakara Tunsophon

    Résumé Résumé Plan Plan  
  • ·Polymorphisms in GNMT and DNMT3b are associated with methotrexate treatment outcome in plaque psoriasis

    Article :111456

    Jasna Grželj, Irena Mlinarič-Raščan, Pij B. Marko, Maruška Marovt, Tanja Gmeiner, Alenka Šmid

    Résumé Résumé Plan Plan   
  • ·Qingfei oral liquid inhibited autophagy to alleviate inflammation via mTOR signaling pathway in RSV-infected asthmatic mice

    Article :111449

    Linlin Yu, Jing Wang, Ya Zou, Hairong Zeng, Weiwei Cheng, Xiaoping Jing

    Résumé Résumé Plan Plan  
  • ·919 syrup inhibits ROS-mediated leptin-induced anorexia by activating PPARγ and improves gut flora abnormalities

    Article :111455

    Jing-Wei Xing, Man-Man Chen, Xin-Yun Tian, Dan-Qing Pan, Xiu-Hua Peng, Peng-Fei Gao

    Résumé Résumé Plan Plan   
  • ·Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma multiforme

    Article :111461

    Liying Wang, Xiangbo Wang, Lina Shen, Majed Alrobaian, Sunil K. Panda, Hussain A. Almasmoum, Mazen M. Ghaith, Riyad A. Almaimani, Ibrahim Abdel Aziz Ibrahim, Tanuja Singh, Abdullah A. Baothman, Hani Choudhry, Sarwar Beg

    Résumé Résumé Plan Plan   
  • ·An integrative strategy for discovery of functional compound combination from Traditional Chinese Medicine: Danhong Injection as a model

    Article :111451

    Zhixiong Wang, Haofang Wan, Xin Tong, Yu He, Jiehong Yang, Ling Zhang, Chongyu Shao, Zhishan Ding, Haitong Wan, Chang Li

    Résumé Résumé Plan Plan   
  • ·Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission

    Article :111403

    Yan-Nan You, Qiong-Qiong Xing, Xia Zhao, Jian-Jian Ji, Hua Yan, Tao Zhou, Ying-Mei Dong, Li-Shun Ren, Shu-Ting Hou, Yuan-Yuan Ding

    Résumé Résumé Plan Plan   
  • ·Blocking 5-LO pathway alleviates renal fibrosis by inhibiting the epithelial-mesenchymal transition

    Article :111470

    Jian Zhou, Rui Li, Qinhui Liu, Jinhang Zhang, Hui Huang, Cuiyuan Huang, Guorong Zhang, Yingnan Zhao, Tong Wu, Qin Tang, Ya Huang, Zijing Zhang, Yanping Li, Jinhan He

    Résumé Résumé Plan Plan   
  • ·Analysis of jejunum microbiota of HFD/STZ diabetic rats

    Article :111094

    Babiker Saad Almugadam, Peng Yang, Li Tang

    Résumé Résumé Plan Plan  
  • ·Study on the antidepressant effect of panaxynol through the IκB-α/NF-κB signaling pathway to inhibit the excessive activation of BV-2 microglia

    Article :111387

    Yan Zhao, Xialin Sun, Tingwen Zhang, Shuangli Liu, Enbo Cai, Hongyan Zhu

    Résumé Résumé Plan Plan  
  • ·Evaluation of hesperetin-loaded on multiple wall carbon nanotubes on cerebral ischemia/reperfusion injury in rats

    Article :111467

    Akbar Hajizadeh Moghaddam, Yusef Shirej Pour, Seyed Reza Mokhtari Sangdehi, Vahid Hasantabar

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  • ·Inhibition of NF-κB by ACT001 reduces fibroblast activity in idiopathic pulmonary fibrosis

    Article :111471

    Jade Jaffar, Ian Glaspole, Karen Symons, Glen Westall

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  • ·Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A

    Article :111463

    Xidi Wang, Jesusa L. Rosales, Xu Gao, Ki-Young Lee

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  • ·Preparation of double-layer nanoemulsions with controlled release of glucose as prevention of hypoglycemia in diabetic patients

    Article :111464

    Razie Razavi, Reza Esmaeilzadeh Kenari, Jamshid Farmani, Mohsen Jahanshahi

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  • ·Salvianolic acid B inhalation solution enhances antifibrotic and anticoagulant effects in a rat model of pulmonary fibrosis

    Article :111475

    Tianyi Zhang, Mengjiao Liu, Yunhang Gao, Han Li, Ling Song, Hongping Hou, Tengfei Chen, Lina Ma, Guangping Zhang, Zuguang Ye

    Résumé Résumé Plan Plan  
  • ·A small molecular multi-targeting tyrosine kinase inhibitor, anlotinib, inhibits pathological ocular neovascularization

    Article :111493

    Chang Lu, Qiuyang Zhang, Huiying Zhang, Xiumiao Li, Qin Jiang, Jin Yao

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  • ·Parecoxib improves atherosclerotic plaque stability by suppressing inflammation and inhibiting matrix metalloproteinases production

    Article :111423

    Chao Gong, Yu Qi, Yang Xu, Xiruo Tang, Feng Liang, Lianhua Chen

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  • ·Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion: Insight from an international STEMI registry

    Article :111469

    Giuseppe De Luca, Miha Cercek, Lisette Okkels Jensen, Oliver Bushljetikj, Lucian Calmac, Tom Johnson, Montserrat Gracida Blancas, Vladimir Ganyukov, Wojtek Wojakowski, Clemens von Birgelen, Alexander IJsselmuiden, Bernardo Tuccillo, Francesco Versaci, Jurrien Ten Berg, Mika Laine, Tim Berkout, Gianni Casella, Petr Kala, Bernabé López Ledesma, Victor Becerra, Roberto Padalino, Andrea Santucci, Xavier Carrillo, Alessandra Scoccia, Giovanni Amoroso, Arpad Lux, Tomas Kovarnik, Periklis Davlouros, Gabriele Gabrielli, Xacobe Flores Rios, Nikola Bakraceski, Sébastien Levesque, Vincenzo Guiducci, Michał Kidawa, Lucia Marinucci, Filippo Zilio, Gennaro Galasso, Enrico Fabris, Maurizio Menichelli, Stephane Manzo, Gianluca Caiazzo, Jose Moreu, Juan Sanchis Forés, Luca Donazzan, Luigi Vignali, Rui Teles, Pierfrancesco Agostoni, Francisco Bosa Ojeda, Heidi Lehtola, Santiago Camacho-Freiere, Adriaan Kraaijeveld, Ylitalo Antti, Gabriella Visconti, Iñigo Lozano Martínez-Luengas, Bruno Scheller, Dimitrios Alexopulos, Raul Moreno, Elvin Kedhi, Giuseppe Uccello, Benjamin Faurie, Alejandro Gutierrez Barrios, Fortunato Scotto Di Uccio, Bor Wilbert, Giuliana Cortese, Maurits T. Dirksen, Guido Parodi, Monica Verdoia

    Résumé Résumé Plan Plan  
  • ·Rhizoma drynariae total flavonoids inhibit the inflammatory response and matrix degeneration via MAPK pathway in a rat degenerative cervical intervertebral disc model

    Article :111466

    Kai Zhao, Min Chen, Ting Liu, Panpan Zhang, Sheng Wang, Xiangguo Liu, Qunan Wang, Jie Sheng

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  • ·A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling

    Article :111485

    Ting-Yu Chang, Kunal Nepali, Yi-Ying Chen, Yu-Chen S.H. Yang, Kai-Cheng Hsu, Yun Yen, Shiow-Lin Pan, Jing-Ping Liou, Sung-Bau Lee

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  • ·Ginsenoside Rd attenuates mouse experimental autoimmune neuritis by modulating monocyte subsets conversion

    Article :111489

    Kaixi Ren, Sanzhong Li, Jiaqi Ding, Sijia Zhao, Shiqian Liang, Xiuli Cao, Changjun Su, Jun Guo

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  • ·A nuclear factor-kappa B inhibiting peptide suppresses innate immune receptors and gliosis in a transgenic mouse model of Alzheimer’s disease

    Article :111405

    Alison Lindsay, Deborah Hickman, Mythily Srinivasan

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  • ·Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells

    Article :111483

    Mohamed Qasim Al-Fahdawi, Faris A.J. Al-Doghachi, Qasim Khlaif Abdullah, Ruaa Tareq Hammad, Abdullah Rasedee, Wisam Nabeel Ibrahim, Hussah Abdullah Alshwyeh, Areej A Alosaimi, Sahar Khamees Aldosary, Eltayeb E.M. Eid, Rozita Rosli, Y.H. Taufiq-Yap, Nagi A. Al-Haj, Mothanna Sadiq Al-Qubaisi

    Résumé Résumé Plan Plan  
  • ·Aqueous extract of Taxus chinensis var. mairei regulates the Hippo-YAP pathway and promotes apoptosis of non-small cell lung cancer via ATF3 in vivo and in vitro

    Article :111506

    Gaochenxi Zhang, Shuying Dai, Yiyi Chen, Haibin Wang, Ting Chen, Qijin Shu, Shuyi Chen, Liumei Shou, Xiaolu Cai

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  • ·Cajanolactone A, a stilbenoid from Cajanus cajan, inhibits energy intake and lipid synthesis/storage, and promotes energy expenditure in ovariectomized mice

    Article :111491

    Zhuo-Hui Luo, Jia-Wen Huang, Qi-Qi Meng, Hui-Wen Wu, Rui-Yi Yang, Lin-Chun Fu, Ying-Jie Hu, Xiao-Ling Shen

    Résumé Résumé Plan Plan  
  • ·Melatonin protects rats testes against bleomycin, etoposide, and cisplatin-induced toxicity via mitigating nitro-oxidative stress and apoptosis

    Article :111481

    Mojtaba Moradi, Nader Goodarzi, Azita Faramarzi, Hadi Cheraghi, Amir Hossein Hashemian, Cyrus Jalili

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  • ·Preliminary study on the possible impact of Thalassodendron ciliatum (Forss.) den Hartog acidic polysaccharide fractions against TAA induced liver failure

    Article :111502

    Walaa S.A. Mettwally, Tamer I.M. Ragab, Abdel-Hamid A. Hamdy, Wafaa A. Helmy, Sohair Aly Hassan

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  • ·Eugenia uniflora and Syzygium samarangense extracts exhibit anti-trypanosomal activity: Evidence from in-silico molecular modelling, in vitro, and in vivo studies

    Article :111508

    Mohamed A.O. Abdelfattah, Mohammed Auwal Ibrahim, Hadiza Lawal Abdullahi, Raphael Aminu, Saad Bello Saad, Sonja Krstin, Michael Wink, Mansour Sobeh

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  • ·Alterations in neurotransmitter levels and transcription factor expression following intranasal buprenorphine administration

    Article :111515

    Sanelisiwe P. Xhakaza, Leon J. Khoza, Advaitaa M. Haripershad, Terisha Ghazi, Shanel Dhani, Cosmas Mutsimhu, Molopa J. Molopa, Nithia P. Madurai, Lorna Madurai, Sanil D. Singh, Nirmala D. Gopal, Hendrik G. Kruger, Thavendran Govender, Anil Chuturgoon, Tricia Naicker, Sooraj Baijnath

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  • ·Macro- and microtranscriptomic evidence of the monocyte recruitment to regenerating liver after partial hepatectomy in mouse model

    Article :111516

    Andrey Elchaninov, Maria Nikitina, Polina Vishnyakova, Anastasia Lokhonina, Andrey Makarov, Gennady Sukhikh, Timur Fatkhudinov

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  • ·Emu Oil and Saireito in combination reduce tumour development and clinical indicators of disease in a mouse model of colitis-associated colorectal cancer

    Article :111478

    Lauren C. Chartier, Junko Fujino, Gordon S. Howarth, Jona Freysdottir, Ingibjorg Hardardottir, Suzanne Mashtoub

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  • ·The effects and mechanism of Kangfuxin on improving healing quality and preventing recurrence of gastric ulcer

    Article :111513

    Ming Tian, Jiaoyun Dong, Zhengting Wang, Shuliang Lu, Funeng Geng

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  • ·Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity

    Article :111501

    Mengying Hong, Dongdong Chen, Zhuping Hong, Kejun Tang, Yuanyuan Yao, Liubo Chen, Tingting Ye, Jing Qian, Yushen Du, Ren Sun

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  • ·Protein O-GlcNAcylation alleviates small intestinal injury induced by ischemia-reperfusion and oxygen-glucose deprivation

    Article :111477

    Ruochen Cong, Linlin Sun, Jushun Yang, Hengxiang Cui, Xin Ji, Jing Zhu, Jin-hua Gu, Bosheng He

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  • ·Health properties of the Italian San Martino® mineral-rich water: A self-controlled pilot study

    Article :111509

    Maria Pina Dore, Giovanni Mario Pes, Giuseppe Realdi

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  • ·Rhubarb extract relieves constipation by stimulating mucus production in the colon and altering the intestinal flora

    Article :111479

    Chen-Chen Gao, Guang-Wen Li, Tian-Tian Wang, Lei Gao, Fei-Fei Wang, Hong-Wei Shang, Ze-Jun Yang, Yue-Xin Guo, Bo-Ya Wang, Jing-Dong Xu

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  • ·Glycyrrhizin mitigates inflammatory bone loss and promotes expression of senescence-protective sirtuins in an aging mouse model of periprosthetic osteolysis

    Article :111503

    Chiaki Yamada, Anny Ho, Juliet Akkaoui, Christopher Garcia, Carolina Duarte, Alexandru Movila

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  • ·Andiroba oil and nanoemulsion (Carapa guianensis Aublet) reduce lesion severity caused by the antineoplastic agent doxorubicin in mice

    Article :111505

    Karina Motta Melo, Luiz Fernando Silva Oliveira, Rossineide Martins da Rocha, Maria Auxiliadora Pantoja Ferreira, Maria Luiza Fascineli, Susana Suely Rodrigues Milhomem-Paixão, Cesar Koppe Grisolia, Alberdan Silva Santos, Hugo Leonardo Crisóstomo Salgado, Luiz Alexandre Muehlmann, Ricardo Bentes Azevedo, Julio Cesar Pieczarka, Cleusa Yoshiko Nagamachi

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  • ·Positive or negative anteromedial cortical support of unstable pertrochanteric femoral fractures: A finite element analysis study

    Article :111473

    Qin Shao, Yue Zhang, Gui-Xin Sun, Chen-Song Yang, Na Liu, Da-Wei Chen, Biao Cheng

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  • ·Antithrombotic and anticoagulant effects of a novel protein isolated from the venom of the Deinagkistrodon acutus snake

    Article :111527

    Jin Huang, Wei Song, Haibing Hua, Xiaojian Yin, Fang Huang, Raphael N. Alolga

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  • ·The histamine H3R and dopamine D2R/D3R antagonist ST-713 ameliorates autism-like behavioral features in BTBR T+tf/J mice by multiple actions

    Article :111517

    Karthikkumar Venkatachalam, Nermin Eissa, Mohamed Al Awad, Petrilla Jayaprakash, Sicheng Zhong, Frauke Stölting, Holger Stark, Bassem Sadek

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  • ·Mechanism of rutaecarpine on ethanol-induced acute gastric ulcer using integrated metabolomics and network pharmacology

    Article :111490

    Sichen Ren, Ying Wei, Ming Niu, Ruisheng Li, Ruilin Wang, Shizhang Wei, Jianxia Wen, Dan Wang, Tao Yang, Xing Chen, Shihua Wu, Yuling Tong, Manyi Jing, Haotian Li, Min Wang, Yanling Zhao

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  • ·4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation

    Article :111504

    I-Chuan Yen, Qain-Wen Tu, Tsu-Chung Chang, Pei-Hsun Lin, Yao-Feng Li, Shih-Yu Lee

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  • ·Polyphenol-rich leaf of Aphanamixis polystachya averts liver inflammation, fibrogenesis and oxidative stress in ovariectomized Long-Evans rats

    Article :111530

    Md. Mizanur Rahman, Nusaira Beenta Shahab, Pintu Miah, Md Mahamudur Rahaman, Arafat Ulla Kabir, Nusrat Subhan, Ahad Ali Khan, Mirola Afroze, Mala Khan, K. Shahin Ahmed, Hemayet Hossain, Md. Areeful Haque, Md Ashraful Alam

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  • ·AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose

    Article :111476

    Zhongwen Zhang, Hongxia Wu, Shuhong Huang, Liping Chen, Xinlong Chen, Wei Zhang, Lin Liao, Xiaoqian Zhang

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  • ·Total flavonoids of rhizoma drynariae ameliorates bone formation and mineralization in BMP-Smad signaling pathway induced large tibial defect rats

    Article :111480

    Weipeng Sun, Minying Li, Yan Zhang, Yingjie Huang, Qunzhang Zhan, Yueyi Ren, Hang Dong, Jiena Chen, Zige Li, Chun Fan, Feng Huang, Zhen Shen, Ziwei Jiang

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  • ·Therapeutic potentiality of a new flavonoid against ketamine induced glutamatergic dysregulation in schizophrenia: In vivo and in silico approach

    Article :111453

    Chintha Venkataramaiah, Sholapuri Payani, Bandila Lakshmi Priya, Jangampalli Adi Pradeepkiran

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  • ·Investigation of the impacts of zamzam water on streptozotocin-induced diabetic nephropathy in rats. In-vivo and in-vitro study

    Article :111474

    Waleed El Maleky, Amal M. Mahfoz, Afaf O. Osman, Hekma A. Abd El-Latif

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  • ·Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial

    Article :111526

    Marcelo Augusto Duarte Silveira, David De Jong, Andresa Aparecida Berretta, Erica Batista dos Santos Galvão, Juliana Caldas Ribeiro, Thiago Cerqueira-Silva, Thais Chaves Amorim, Luis Filipe Miranda Rebelo da Conceição, Marcel Miranda Dantas Gomes, Maurício Brito Teixeira, Sergio Pinto de Souza, Marcele Helena Celestino Alves dos Santos, Raissa Lanna Araújo San Martin, Márcio de Oliveira Silva, Monique Lírio, Lis Moreno, Julio Cezar Miranda Sampaio, Renata Mendonça, Silviana Salles Ultchak, Fabio Santos Amorim, João Gabriel Rosa Ramos, Paulo Benigno Pena Batista, Suzete Nascimento Farias da Guarda, Ana Verena Almeida Mendes, Rogerio da Hora Passos, for the BeeCovid Team

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  • ·GYY4137 attenuates functional impairment of corpus cavernosum and reduces fibrosis in rats with STZ-induced diabetes by inhibiting the TGF-β1/Smad/CTGF pathway

    Article :111486

    Bedoor Qabazard, Mariam Yousif, Alyaa Mousa, Oludotun Adebayo Phillips

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  • ·Downregulation of MMP1 expression mediates the anti-aging activity of Citrus sinensis peel extract nanoformulation in UV induced photoaging in mice

    Article :111537

    Reham I. Amer, Shahira M. Ezzat, Nora M. Aborehab, Mai F. Ragab, Dalia Mohamed, Amira Hashad, Dalia Attia, Maha M. Salama, Mahitab H. El Bishbishy

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  • ·Linking the IL-17A immune response with NMR-based faecal metabolic profile in IBD patients treated with Mastiha

    Article :111535

    Charalampia Amerikanou, Eirini Dimitropoulou, Aristea Gioxari, Efstathia Papada, Anthi Tanaini, Charalambos Fotakis, Panagiotis Zoumpoulakis, Andriana C. Kaliora

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  • ·Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats

    Article :111410

    Mohammad H. Abukhalil, Osama Y. Althunibat, Saleem H. Aladaileh, Wesam Al-Amarat, Heba M. Obeidat, Alayn' Al-marddyah A. Al-khawalde, Omnia E. Hussein, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Khalid M. Alanazi, Farhan K. Al-Swailmi, Hany H. Arab, Ayman M. Mahmoud

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  • ·PDRN, a natural bioactive compound, blunts inflammation and positively reprograms healing genes in an “in vitro” model of oral mucositis

    Article :111538

    Giacomo Picciolo, Federica Mannino, Natasha Irrera, Domenica Altavilla, Letteria Minutoli, Mario Vaccaro, Vincenzo Arcoraci, Violetta Squadrito, Giuseppe Picciolo, Francesco Squadrito, Giovanni Pallio

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  • ·MiR-96 promotes myocardial infarction-induced apoptosis by targeting XIAP

    Article :111208

    Jianxiu Wang, Guiling Dong, Weifeng Chi, Yingying Nie

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  • ·Herbal medicine WangShiBaoChiWan improves gastrointestinal health in mice via modulation of intestinal tight junctions and gut microbiota and inhibition of inflammation

    Article :111426

    Sheng Yin, Chao Sun, Yi Ji, Hamid Abdolmaleky, Jin-Rong Zhou

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  • ·Drug resistance evaluation in novel 3D in vitro model

    Article :111536

    Marta Nowacka, Karolina Sterzynska, Malgorzata Andrzejewska, Michal Nowicki, Radoslaw Januchowski

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  • ·Morin alleviates hepatic ischemia/reperfusion-induced mischief: In vivo and in silico contribution of Nrf2, TLR4, and NLRP3

    Article :111539

    Abdallah Gendy, Mohamed R. Elnagar, Ayman Soubh, Asmaa Al-Mokaddem, Alaadin El-Haddad, Mohamed Kotb El-Sayed

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  • ·Hyperoside prevents sepsis-associated cardiac dysfunction through regulating cardiomyocyte viability and inflammation via inhibiting miR-21

    Article :111524

    Jun Zhang, Yujuan Liu, Lijun Liu

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  • ·Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity

    Article :111531

    Ke Feng, Yuxin Liu, Jia Sun, Chunlai Zhao, Yajun Duan, Wenjia Wang, Kaijing Yan, Xijun Yan, He Sun, Yunhui Hu, Jihong Han

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  • ·Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1

    Article :111543

    Xingyu Ma, Xiaoli Li, Qianqian Di, Xibao Zhao, Ruihan Zhang, Yue Xiao, Ping Sun, Haimei Tang, Jiazheng Quan, Weilie Xiao, Weilin Chen

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  • ·Therapeutic effect of modulating the NLRP3-regulated transforming growth factor-β signaling pathway on interstitial cystitis/bladder pain syndrome

    Article :111522

    Hung-Jen Shih, Chao-Yuan Chang, Chung-Howe Lai, Chun-Jen Huang

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  • ·The toxicity mechanism of toxic compounds from Euphorbiae pekinensis Radix on zebrafish embryos

    Article :111521

    Wei-ni Qin, Kai-cheng Zhang, Ting Geng, Fang-fang Cheng, Pei-dong Chen, Wei-feng Yao, Li Zhang, Yu-dan Cao

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  • ·FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway

    Article :111532

    Hong Wang, Minyi Huang, Weijian Bei, Yiqi Yang, Lixia Song, Dongxing Zhang, Wenjing Zhan, Yuzhen Zhang, Xu Chen, Weixuan Wang, Lexun Wang, Jiao Guo

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  • ·The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro

    Article :111305

    Mengmeng Wang, Yingying Ke, Yage Li, Zengfu Shan, Wangyang Mi, Yangang Cao, Weisheng Feng, Xiaoke Zheng

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• Letter to the Editor

  • ·Correspondence on ‘A. Grylls, K. Seidler, J. Neil, Link between microbiota and hypertension: Focus on LPS/TLR4 pathway in endothelial dysfunction and vascular inflammation, and therapeutic implication of probiotics’

    Article :111432

    Marco Tullio Suadoni

    
  • ·2′,7′-Dichlorofluorescein (DCF) or 2′,7′-dichlorodihydrofluorescein diacetate (DCFH2-DA) to measure reactive oxygen species in erythrocytes

    Article :111512

    Chander Hans, Rahul Saini, Man Updesh Singh Sachdeva, Prashant Sharma

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